NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL_RS14115 [old locus tag: SACOL2698 ]
- pan locus tag?: SAUPAN006429000
- symbol: SACOL_RS14115
- pan gene symbol?: hisA
- synonym:
- product: 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL_RS14115 [old locus tag: SACOL2698 ]
- symbol: SACOL_RS14115
- product: 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase
- replicon: chromosome
- strand: -
- coordinates: 2771644..2772348
- length: 705
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661ATGATTGAATTATGGCCAGCGATTGATTTGATTGGGTCAACAAGTGTGAGGTTAACAGAG
GGTAAATATGATAGTGAAGAAAAAATGTCACGCTCGGCTGAAGAAAGTATTGCTTACTAT
AGTCAATTTGAATGTGTGAATCGTATTCATATCGTCGACTTGATAGGTGCTAAGGCACAG
CATGCCCGAGAGTTTGATTATATTAAGTCATTGAGGAGATTAACAACCAAAGATATTGAA
GTAGGTGGTGGCATTCGTACGAAGTCACAAATCATGGACTACTTTGCCGCAGGGATTAAT
TATTGCATAGTTGGAACGAAAGGTATTCAAGATACTGATTGGCTTAAAGAGATGGCACAT
ACATTTCCAGGTCGCATTTATTTATCTGTTGATGCCTATGGAGAAGATATTAAAGTGAAC
GGATGGGAAGAGGACACAGAGTTAAATTTATTTAGTTTTGTGAGACGGTTATCGGATATA
CCTCTTGGCGGCATTATATATACTGATATTGCTAAAGATGGCAAAATGTCCGGACCTAAC
TTTGAATTAACTGGTCAATTAGTAAAGGCAACGACGATTCCTGTCATTGCTTCCGGTGGT
ATTAGACATCAGCAAGATATTCAACGATTAGCGTCGCTAAATGTTCACGCTGCTATTATA
GGAAAGGCTGCACATCAAGCATCTTTTTGGGAGGGGCTAAAATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL_RS14115 [old locus tag: SACOL2698 ]
- symbol: SACOL_RS14115
- description: 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase
- length: 234
- theoretical pI: 5.9599
- theoretical MW: 26090.5
- GRAVY: -0.185897
⊟Function[edit | edit source]
- ⊞reaction: EC 5.3.1.16? ExPASy
- ⊞TIGRFAM: Amino acid biosynthesis Histidine family 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase (TIGR00007; EC 5.3.1.16; HMM-score: 248.4)and 16 more
- TheSEED: see SACOL2698
- ⊞PFAM: TIM_barrel (CL0036) His_biosynth; Histidine biosynthesis protein (PF00977; HMM-score: 209.6)and 12 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDTDWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRRLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: CodY, HisR* see SACOL2698
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available