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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_RS14750 [old locus tag: NWMN_2570 ]
- pan locus tag?: SAUPAN006427000
- symbol: NWMN_RS14750
- pan gene symbol?: hisI
- synonym:
- product: bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_RS14750 [old locus tag: NWMN_2570 ]
- symbol: NWMN_RS14750
- product: bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase
- replicon: chromosome
- strand: -
- coordinates: 2839708..2840340
- length: 633
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
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421
481
541
601ATGACCAAATATAAAATTGATTTTAGCAAAGGTTTAGTGCCAGCAATTTTACAAGATAAT
CAAACAAAACAAGTATTGATGTTGGGTTATATGAACCAAGAAGCTTTTGATAAAACGATA
GAAGATGGTGTGGTATGTTTCTATTCGCGGTCGAAACAACGGCTATGGACAAAAGGTGAA
ACATCTGGTCATACGCAACGTGTTAAAGATATTCATGTAGATTGCGACAATGACACTATT
TTAATTGATGTCATACCAAATGGACCAACATGTCATACAGGCAGTCAAAGTTGTTTCAAC
ACAGAAGTTCCATTTTCAGTGCAAACATTAGCGCAGACAGTTCAAGATAGTGCCCAATCC
AATAATGAAAAGTCATATACAAAATATTTATTAACAGAAGGTATAGAAAAGATTACAAAA
AAATACGGTGAAGAAGCTTTTGAAGTCGTAATTGAAGCAATTAAAGGTGACAAAAAAGCA
TTTGTAAGTGAAGTAGCAGATGAACTTTATCATTTATTTGTCTTGATGCATGCGCTTGGC
GTCGATTTTTCAGAAATTGAGGCGGAATTAGCGCGTAGACATCATAAGCGCAATAACTTT
AAAGGTGAACGACAAAATATCGAACAGTGGTAA60
120
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360
420
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540
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633
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_RS14750 [old locus tag: NWMN_2570 ]
- symbol: NWMN_RS14750
- description: bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase
- length: 210
- theoretical pI: 5.899
- theoretical MW: 23986.9
- GRAVY: -0.528571
⊟Function[edit | edit source]
- ⊞reaction: EC 3.5.4.19? ExPASyEC 3.6.1.31? ExPASy
- TIGRFAM: Amino acid biosynthesis Histidine family phosphoribosyl-ATP diphosphatase (TIGR03188; EC 3.6.1.31; HMM-score: 90.8)
- TheSEED: data available for COL, N315, USA300_FPR3757
- ⊞PFAM: no clan defined PRA-CH; Phosphoribosyl-AMP cyclohydrolase (PF01502; HMM-score: 116.5)and 5 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MTKYKIDFSKGLVPAILQDNQTKQVLMLGYMNQEAFDKTIEDGVVCFYSRSKQRLWTKGETSGHTQRVKDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTEVPFSVQTLAQTVQDSAQSNNEKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKAFVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization: data available for COL
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: CodY, HisR* see NWMN_2570
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: no data available
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available