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PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 01-DEC-2025

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: EGJ38_000027 [new locus tag: EGJ38_RS00135 ]
  • pan locus tag?: SAUPAN006529000
  • symbol: cnuC
  • pan gene symbol?: cnuC
  • synonym:
  • alternate name: JSNZ_000027
  • product: nuclease domain-containing protein

⊟Additional information (user-provided)[edit | edit source]

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EGJ38_000027 [new locus tag: EGJ38_RS00135 ]
  • symbol: cnuC
  • product: nuclease domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 33738..35468
  • length: 1731
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq: MGT2422039 NCBI
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    ATGGATTTACATTCTAACTTAGATATAATTGTTAGTAATGGATACCGAGAGAATGTCTAT
    AATATTGTATTCAGAGAATCAATAAAAGATATAAATTTTGAAAAAGATGTATTATCCTTT
    AAAGAGTATCACTCTATGAAATTTCGTCATAAATCTACTGATTATAATGAAAAATTATAT
    TTCAATGGTTTCGACACTATTGTGGACGATATATTAAAAATTGATAAAAAGGGAAATAGT
    TATCTTTCAAACGCTACACTAGATATAATTAATTACACTAGTAATAATGATCAAAATGTA
    CTAGTTCCTGGTTATTATTTATTAACATTGGTCAATGAAAAAACTAAGTATGCCATTATA
    AAAATAGTTCCTAAGGATTTTACTGAGGAAGAGTGGAAATCATTATATGAAGACGTTAAT
    AGTTACTTAAATGGTTTAGCAAATTCATTTGTAAATAGAAATAATGTTACGGTAATTCAA
    AACAAAAAAGACAATAATTTGTATAATAAAATCAATTTCATTGATAAATATTTTATAAAA
    ATAATTAATTCTGTAAATCAATTAATAGTGAACCCTAGGTTAACAATTCAAAAAAATTAT
    AAATGGGTTCCTAAACACACACAACCACATGTCGATAAAAAAACTATTAAATATTCATCT
    AAATATCCAAATAAAACACAATATTTGTATACTTACAAAAGAGTTATTAATTATAATATC
    TCAGAAAATATGTGGTTGAAATTTGTAGTTGAGTTTTTATTAAAAGAACTAAACTCAATT
    GGTAAAGAAATTATTTTGAAAATTGAAAATGAAAATTATAAATATAATTCGAAATATAGT
    AGTGAGATAAAAAAAGCTAAAATTACTAAGAATAATTTAAACCAAGCTAAAAAAAATATT
    ATTATCCTTAAAAATTTAATAATAAAATTAAGAAATAGTGAATGGTATAGTCAAGTTTCC
    TATAAAAATAATATGGTGCCAACTAAATCTTCACTTATGAATCAAAACTATAATTTATTA
    TATACATGGTATGTAGAATTTAATAAAAGTAATTTTGATTTCATCTTTTCTGAACAGGTA
    CTAAATTCATGGAAAAAAACAGATGAACTATATGAGATTTGGTGTTATATCAATATAATT
    GAAATAATAAGAAGTAGTGGTTTTATGCCTGTAAAAGGATGGGTTTTTAATGGGGATATT
    CAAAATGATCTCGATGAAGGTACTTATGTAACAATGAAAAAAGCAGAAACCACTTTAAAT
    ATACACTATAATACACTTCTTAAGTATAAAAGTTCTGAAACTAATTTAGTAAATCCACTT
    TATACTGGAAACAAAAAAAATAAACCCGACATTAGAATTGATATTTTTGTAGGCGGTATA
    TATTTAAAAAGTATACCGATAGAAGCTAAGTACAGAAAACTGAAAAATATAACCGGAGAA
    AAAATGGGATCTCTTAAACAATTACTTGCTTACAGAGATTCTCCAAAATCTTTATTACAT
    TTAGCAGGCGCTAAACACATTAGAAAAAATAACCATACGGTTATTACAAAGGTTATTATT
    TTATACCCTAAAGATACTAGTTCTAACTCTAAAGCTGATATTTTATCTGTTGAGCATGGT
    TTGTTATTCTATGAATTTGGACCTAATTATATAGATACATCATTGAAAACCACATTGATT
    GAAGAAATTAATGAAGCATTTGAAATTTATAATGATATTTATAAAAACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
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    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1731


⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EGJ38_000027 [new locus tag: EGJ38_RS00135 ]
  • symbol: CnuC
  • description: nuclease domain-containing protein
  • length: 576
  • theoretical pI: 9.69351
  • theoretical MW: 67816.2
  • GRAVY: -0.506771

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED:
  • PFAM:
    PDDEXK (CL0236) PDDEXK_7; PD-(D/E)XK nuclease superfamily (PF04411; HMM-score: 30.1)
    DUF2357; Domain of unknown function (DUF2357) (PF09823; HMM-score: 27.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.1453
    • Cytoplasmic Membrane Score: 0.3052
    • Cell wall & surface Score: 0.0016
    • Extracellular Score: 0.5479
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001951
    • TAT(Tat/SPI): 0.000127
    • LIPO(Sec/SPII): 0.000385
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: MGT2422039 NCBI
  • UniProt:

⊟Additional information (user-provided)[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MDLHSNLDIIVSNGYRENVYNIVFRESIKDINFEKDVLSFKEYHSMKFRHKSTDYNEKLYFNGFDTIVDDILKIDKKGNSYLSNATLDIINYTSNNDQNVLVPGYYLLTLVNEKTKYAIIKIVPKDFTEEEWKSLYEDVNSYLNGLANSFVNRNNVTVIQNKKDNNLYNKINFIDKYFIKIINSVNQLIVNPRLTIQKNYKWVPKHTQPHVDKKTIKYSSKYPNKTQYLYTYKRVINYNISENMWLKFVVEFLLKELNSIGKEIILKIENENYKYNSKYSSEIKKAKITKNNLNQAKKNIIILKNLIIKLRNSEWYSQVSYKNNMVPTKSSLMNQNYNLLYTWYVEFNKSNFDFIFSEQVLNSWKKTDELYEIWCYINIIEIIRSSGFMPVKGWVFNGDIQNDLDEGTYVTMKKAETTLNIHYNTLLKYKSSETNLVNPLYTGNKKNKPDIRIDIFVGGIYLKSIPIEAKYRKLKNITGEKMGSLKQLLAYRDSPKSLLHLAGAKHIRKNNHTVITKVIILYPKDTSSNSKADILSVEHGLLFYEFGPNYIDTSLKTTLIEEINEAFEIYNDIYKN

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Additional information (user-provided)[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Other information (user-provided)[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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