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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000571
  • pan locus tag?: SAUPAN002468000
  • symbol: JSNZ_000571
  • pan gene symbol?: —
  • synonym:
  • product: HD domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000571
  • symbol: JSNZ_000571
  • product: HD domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 607204..608499
  • length: 1296
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGACTAACGCATATGTAGATTTAAAATTAGTAGAAGAAAAAGTTTTTAAAGACCCGATA
    CATCGATATATTCATGTTGAAGATCAATTGATATGGGATTTAATTAAAACTAAGGAATTC
    CAAAGGTTACGTCGAATTAGACAACTAGGAACACTGTACCTATCTTTCCACACAGCAGAA
    CATAGTCGCTTTGGACATTCTTTAGGTGTGTATGAAATAGTTAGAAGATTAATTGATGAG
    TCATTTATTGGTCATGATGCATGGGACAATAAAGATAGACCGTTGGCATTATGTGCTGCA
    TTATTACATGATTTAGGACATGGTCCATTTTCACATAGTTTTGAAAAAATATTTAATACA
    GACCATGAAGCATATACACAAGCGATTATTACTGGAGATACTGAGGTGAATGCTGTATTA
    CGTAAAGTGTCGCCTGAGTTTCCAAGAGAAGTTGCGGAAGTAATTAATAAAACGCATCAT
    AATAAATTGGTCATTTCGATGATTTCGTCACAAATCGATGCGGATAGAATGGATTATTTA
    CAACGTGATGCGTATTTCACAGGTGTATCATATGGTGCTTTTGATATGGAACGTATTTTA
    AGATTAATGCGACCTTCTAAAGATGAAGTACTAATCAAAGAAAGTGGTATGCATGCAGTT
    GAAAACTTTATTATGAGTCGTTATCAAATGTATTGGCAGATTTATTTCCACCCAGTTAGT
    CGTGGTGGAGAAGTGCTGCTTAATAATTGTTTGAAACGCGCAAAACAGCTTTATAATGAA
    GGCTATGAATTTAAGTTGCATCCACATGATTTTATTCCATTTTTTGAAGAGACAGTTACG
    ATTGAACAATATGTTGAACTCGATGAAGCGGTAGTTACGTATTATTTGGAAAAATGGACA
    AAAGAAGATGATGCCATTTTAAGTGATTTAGCAAGTCGATTTATTAATCGAGACTTATTT
    AAATATATTCCATTTGATGGCTCAATTATTACAATATCAGAACTGCAAGAACTGTTTGAA
    GCAGGTGGTATTAATCCAGATTATTATTTTGTGAGTGAAGCATTTTCGGATTTGCCATAT
    GACTATGATCGACCTGGGTCAAATCGCAAACCGATTCATTTATTAAGACAAGATGGTACG
    ATTAGAGAAATAAGCAATCAATCATTAGTCATTCATAGTATTACAGGCATTAATCGCCAA
    GACTATAAATTATATTATCCTAGAGAAATGGTTGCAAAGATTAAAGATAAGACAATTAGA
    GAAGCTATTGAAAATTTGATTAATGAGCTTAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1296

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000571
  • symbol: JSNZ_000571
  • description: HD domain-containing protein
  • length: 431
  • theoretical pI: 5.81147
  • theoretical MW: 50611.1
  • GRAVY: -0.391879

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions putative dGTPase (TIGR01353; EC 3.1.5.1; HMM-score: 28.2)
    and 1 more
    HDIG domain (TIGR00277; HMM-score: 12.2)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    HD_PDEase (CL0237) HD; HD domain (PF01966; HMM-score: 50.9)
    no clan defined HD_assoc_2; HD associated region (PF19276; HMM-score: 49)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9599
    • Cytoplasmic Membrane Score: 0.025
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0148
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.000991
    • TAT(Tat/SPI): 0.000202
    • LIPO(Sec/SPII): 0.000192
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVSPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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