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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001746
  • pan locus tag?: SAUPAN004438000
  • symbol: JSNZ_001746
  • pan gene symbol?: sasC
  • synonym:
  • product: YSIRK signal domain/LPXTG anchor domain surface protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001746
  • symbol: JSNZ_001746
  • product: YSIRK signal domain/LPXTG anchor domain surface protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1793768..1800097
  • length: 6330
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
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    481
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    721
    781
    841
    901
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    1021
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    1501
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    1621
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    1981
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    5221
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    6001
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    6241
    6301
    ATGAATTTGTTAAAGAAAAATAAATATAGTATTAGGAAGTATAAAGTAGGCATATTCTCT
    ACTTTAATCGGAACAGTTTTATTACTTTCAAACCCAAATGGTGCACAAGCCTTAACTACG
    GATAATAATGTACAAAGCGATACTAATCAAGCAACACCTGTAAATTCACAAGATAAAGAT
    GTTGCTAATAATAGAGGTTTAGCAAATAGTGCGCAGAATACACCTAATCAATCTGCAACA
    ACCAATCAATCAACGAATCAAGCATTGGTTAATCATAATAATGGTAGTATAGTAAATCAA
    GCTACGCCAACATCAGTGCAATCAAGTACGCCTTCAGCACAAAACAATAATCATACAGAT
    GGCAATACAACAGCAACTGAGACAGTGTCAAACGCTAATAATAATGATGCAGTGTCGAAT
    AATACCACATTAAATGTACCAAATAAAACAAATGAAAATGGTTCAGGAGGACATCTAACT
    TTAAAGGAAATTCAAGAAGATGTTCGTCATTCTTCAGATAAACCAGAGCTAGTTGCAATT
    GCTGAACCAGCATCTAATAGACCGAAAAAGAGAAGTAGACGTGCGGCACCGGCAGATCCT
    AATGCAACTCCAGCAGATCCAGGGGCTGCAGCGGCAGGAAACGGTGGTGCACCAGTTGCA
    ATTACAGCGCCATACACGCCTACAACTGATCCTAATGCCAATAATGCAGGACAAAATGCA
    CCTAACGAAGTGCTGTCATTTGATGACAATAGTATTAGACCAAGTACCAACCGTTCTGTA
    CCATCAGTAACAGTTGTTGATAATTTACCAGGCTTTACACTTATCAATGGTGGTAAAGTA
    GGTGTGCTAAGTCATGCGATGGTTAGAACAAGTATGTTTGAGGCTGGGAGCAACAGAACC
    TATCAGGCACAAGGCAATGTACTTGCATTAGGACGTATAAGCGGGACGGACGCTAGTAAT
    CATGGAGATTTTAATGGTATTGAAAAATCTTTAACAGTAAATCCAAATTCTGAATTAATC
    TTTGAATTTAATACAATGACTACTAAAAACGGTCAAGGCGCAACAAATGTTATTATCAAA
    AATGCTGATACTAATGATACGATTGCTGAAAAGACTGTTGAAGGCGGTCCAACTTTGCGT
    TTATTTAAAGTACCTGATAATGTGAGAAATCTCAAAATTCAATTTGTACCTAAAAATGAC
    GCAATAACAGATGCGCGTGGCATTTATCAACTAAAAGATGGTTACAAATACTATAGCTTT
    GTTGACTCTATCGGACTTCATTCTGGGTCACATGTTTATGTTGAAAGACGAACAATGGAT
    CCAACAGCAACAAATAATAAAGAGTTTACTGTAACAACATCATTAAAGAATAATGGTAAT
    TCTGGTGCTTCTCTAGATACAAATGACTTTGTATATCAAGTTCAATTACCTGAAGGTGTT
    GAATATGTGAACAATTCATTGACTAAAGATTTTCCAAGTAACAATTCAGGCGTTGATGTT
    AATGATATGAATGTTACATATGATGCAGCAAATCGTGTGATAACAATTAAAAGTACTGGA
    GGAGGTACAGCAAACTCTCCGGCACGACTTATGCCTGATAAAATACTCGATTTAAGATAT
    AAATTACGTGTAAATAATGTGCCGACACCAAGAAGAGTAACATTTAACGAGACATTAACG
    TATAAAACATATACACAAGATTTCATTAATTCACCTGCTGAAAGTCATACTGTAAGTACA
    AATCCATATACTATCGATATCATCATGAATAAAGATGCATTACAAGCCGAAGTTGACAGA
    CGCATTCAACAAGCTGATTATACATTTGCATCATTAGATATCTTTAATGATCTTAAAAAA
    CGTGCACAAACAATTTTAGCTGAAAATCGTAACAATGTACCATTAAATAAAAGAGTATCT
    CAAGCAGATATTGATACATTAACTAATCAGATGCAACATACTTTAATTCGAAGTGTTGAT
    GCTGAAAATGCAGTAAATCAAAAAGCTGATCAAATGGAAGATTTAGTTAATCAAAATGAT
    GAACTGACAGATGAAGAAAAACAAGCAGCAATACAAGTTATCGAGGAACATAAAGGCAAT
    ATTATTGGTGATATTGGTGATCAAACGACTGATGACGGCGTTACTAGAATCAAAGATCAA
    GGTATACAGACCTTAAGTGGGGATACTGCAACACCGGTTGTTAAACCAAATGCTAAAAAA
    GCAATACGTGATAAAGCAACGAAACAAAGGGAAATTATCAATGCAACACCAGATGCTACT
    GAAGACGAGATTCAAGATGCAATAAATCAATTAGCTACGGATGAAACAGATGCTATTGAT
    AATGTTACGAATGCTACTACAAATGCTGACGTTGAAACAGCTAAAAATAATGGCATCAAT
    ACTATTGGAGCAGTTGTTCCTCAAGTAACTCATAAAAAAGCTGCAAGAGATGCAATTAAC
    CAAGCAACAGCAACGAAAAGACAACAAATAAATAGTAATAGAGAAGCAACTCAGGAAGAG
    AAAAATGCAGCATTGAACGAATTAACTCAAGCAACCAACCATGCTTTAGAACAAATCAAT
    CAAGCAACAACAAATGCTGATGTTGATAACGCCAAAGGAGATGGTCTAAATGCCATTAAT
    CCAATTGCTCCTGTAACTGTTGTTAAGCAAGCTGCAAGGGATGCCGTATCACATGATGCA
    CAACAACATATCGCAGAGATCAATGCTAATCCTGATGCGACTCAAGAAGAAAGACAAGCA
    GCAATTGACAAAGTGAATGCTGCTGTAACTGCAGCAAACACAAACATTTTAAACGCTAAT
    ACCAATGCTGAAGTGGAACAAGTGAAGACAAATGCGATACAAGGAATACAAGCAATTACA
    CCAGCTACAAAGGTAAAAACAGATGCAAAAAATGCCATCGATAAAAGTGCGGAAACGCAA
    CATAATACGATATTTAATAATAATGATGCGACGCTCGAAGAACAACAAGCAGCACAACAA
    TTACTTGATCAAGCTGTAGCCACAGCGAAGCAAAATATTAATGCAGCAGATACGAATCAA
    GAAGTTGCACAAGCAAAAGATCAGGGCACACAAAATATAGTAGTGATTCAACCGGCAACA
    CAAGTTAAAACGGATGCTCGCAATGTTGTAAATGATAAAGCGCGAGAGGCGATAACAAAT
    ATCAATGCTACACCTGGCGCGACTCGAGAAGAGAAACAAGAAGCGATAAATCGTGTCAAT
    ACACTTAAATATAGAGCATTAACTGATATTGGTGTGACATCTACTACTGCGATGGTCAAT
    AGTATTAGAGACGATGCAGTCAATCAAATCGGCGCAGTTCAACCGCATGTAACGAAGAAA
    CAAACTGCTACAGGTGTATTAAATGATTTAGCAACTGCTAAAAAGCAAGAAATTAATCAA
    AACACAAATGCAACAACTGAAGAAAAGCAAGTGGCTTTAAATCAAGTGGATCAAGAGTTA
    GCAACGGCAATTAATAATATAAATCAAGCTAACACAAATGCAGAAGTAGACCAAGCTGCG
    ACAGTAGCAGAGAATAATATCGATGCTGTTCAAGTTGACGTAGTAAAAAAACAAGCAGCG
    CGAGATAAAATCACTGCTGAAGTGGCGAAGCGTATTGAAGCGGTTAAACAAACACCTAAT
    GCAACTGACGAAGAAAAGCAGGCTGCTGTTAATCAAATCAATCAACTTAAAGATCAAGCA
    TTTAATCAAATTAATCAAAACCAAACAAATGATCAGGTAGACGCAACTACAAATCAAGCG
    GTAAATGCTATAGATAATGTTGAAGCTGAAGTAGTAATTAAACCAAAGGCAATTGCAGAT
    ATTGAAAAAGCTGTTAAAGAAAAGCAACAGCAAATTGATAATAGTCTTGATTCAACAGAT
    AATGAGAAAGAAGTTGCTTCACAAGCATTAGCAAAAGAAAAAGAAAAAGCACTTGCAGCT
    ATTGACCAAGCTCAAACGAATAGTCAGGTGAATCAAGCAGCAACAAATGGTGTATCAGCG
    ATTAAAATTATTCAACCTGAAACAAAAGTTAAACCAGCTGCACGTGAAAAAATCAATCAA
    AAAGCGAATGAATTACGTGCTAAGATTAATCAGGATAAAGAAGCAACAGCAGAAGAAAGA
    CAAGTAGCACTAGATAAAATCAATGAATTTGTAAATCAAGCCATGACAGATATTACGAAT
    AATAGAACAAATCAACAAGTTGATGATACAACAAGTCAAGCGCTTGATAGCATTGCTTTA
    GTGACGCCTGACCATATTGTTAGAGCAGCTGCTAGAGATGCAGTTAAGCAACAATATGAA
    GCTAAAAAGCGCGAAATTGAGCAAGCGGAACATGCGACTGATGAAGAAAAACAAGTTGCT
    TTAAATCAATTAGCGAATAATGAAAAACGTGCATTACAAAACATCGATCAAGCAATAGCG
    AATAATGATGTGAAACGTGTTGAAACAAATGGCATTGCTACACTAAAAGGTGTACAACCT
    CATATTGTAATTAAGCCTGAAGCACAACAAGCAATAAAAGCAAGTGCAGAAAATCAAGTA
    GAATCAATAAAAGATACACCACATGCAACAGTTGATGAATTAGATGAAGCGAATCAATTA
    ATTAGCGACACACTCAAACAAGCGCAACAAGAAATAGAAAATACAAATCAAGATGCTGCT
    GTTACTGATGTTAGAAATCAAACAATCAAGGCAATAGAGCAAATAAAACCTAAAGTAAGA
    CGTAAACGAGCTGCGCTTGATAGCATTGAAGAAAATAATAAAAATCAACTCGATGCAATC
    CGAAATACGTTGGATACTACTCAAGATGAAAGAGATGTTGCTATTGATACTTTAAATAAA
    ATTGTAAATACAATTAAAAATGACATTGCACAAAACAAAACGAATGCAGAAGTGGATCGA
    ACTGAGACTGATGGCAACGACAACATCAAAGTGATTTTACCTAAAGTTCAAGTTAAACCA
    GCAGCGCGTCAATCTGTTGGTGTAAAAGCCGAAGCTCAAAATGCACTAATCGATCAAAGC
    GATTTATCAACTGAAGAAGAAAGACTAGCTGCTAAACATTTAGTAGAACAAGCACTTAAT
    CAGGCTATTGATCAGATCAATCATGCAGATAAGACTGCCCAAGTTAATCAAGATAGTATA
    GATGCTCAAAATATTATTTCAAAAATTAAACCAGCGACAACAGTTAAAGCAACAGCATTA
    CAACAAATTCAAAATATCGCTACAAATAAAATTAATTTAATTAAAGCAAATAACGAAGCG
    ACAGATGAAGAACAAAATATTGCAATAGCACAAGTTGAAAAAGAGTTAATTAAAGCTAAA
    CAACAAATTGCTAGTGCAGTGACTAATGCTGATGTGGCATATTTATTGCATGATGAGAAA
    AACGAAATTCGTGAAATCGAACCTGTTATTAGCAGAAAGGCGTCTGCTCGAGAACAATTG
    ACAACATTATTCAACGATAAAAAACAAGCAATTGAAGCGAATATTCAAGCAACGGTAGAA
    GAAAGAAATAGTATATTAGCACAGTTACAAAATATTTATGACACTGCTATTGGACAAATT
    GATCAAGATCGTAGCAATGCACAAGTTGATAAAACAGCATCATTAAATCTACAAACAATA
    CATGATTTAGATGTACATCCTATTAAAAAGCCAGATGCTGAAAAAACGATTAATGATGAT
    CTTGCACGCGTCACTGCTTTAGTGCAAAATTATCGAAAAGTAAGTGATCGTAATAAGGCT
    GATGCATTAAAAGCTATAACTGCTTTAAAATTACAAATGGATGAAGAATTAAAAACAGCA
    CGCACTAATGCTGATGTTGATGCAGTTTTAAAACGATTTAATGTTGCATTAAGCGATATA
    GAAGCAGTAATTACTGAAAAAGAAAATAGTTTACTGCGCATTGATAACATTGCTCAACAA
    ACATATGCGAAATTCAAAGCGATCGCAACACCAGAACAATTAGCTAAAGTAAAAGTATTA
    ATTGATCAATATGTTGCAGATGGCAATAGAATGATTGATGAAGATGCGACATTAAATGAC
    ATCAAACAACATACGCAATTCATTGTTGATGAAATTTTAGCAATTAAATTACCAGCTGAA
    GCGATGAAAGTATCACCAAAAGTAATTCAGCCAGCTCCAAAAGTTTGTACGCCTATTAAA
    AAAGAAGAGACACATGAATCGCGCAAAGTTGAAAAAGAACTTCCAAATACAGGTTCTGAA
    GGAATGGATTTACCATTGAAAGAATTTGCACTGATTACAGGTGCGGCTTTGTTAGCTAGA
    AGACGTACTAAAAACGAAAAAGAATCATAA
    60
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    6300
    6330

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001746
  • symbol: JSNZ_001746
  • description: YSIRK signal domain/LPXTG anchor domain surface protein
  • length: 2109
  • theoretical pI: 4.94269
  • theoretical MW: 229691
  • GRAVY: -0.662873

⊟Function[edit | edit source]

  • TIGRFAM:
    SasC/Mrp/FmtB intercellular aggregation domain (TIGR04263; HMM-score: 396.8)
    and 2 more
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 35)
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 17.3)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    B_GA (CL0598) DUF1542; Domain of Unknown Function (DUF1542) (PF07564; HMM-score: 893.6)
    and 1 more
    no clan defined YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 42.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 0
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0038
    • Cytoplasmic Membrane Score: 0.0045
    • Cell wall & surface Score: 0.8623
    • Extracellular Score: 0.1294
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.99241
    • TAT(Tat/SPI): 0.003234
    • LIPO(Sec/SPII): 0.000883
    • Cleavage Site: CS pos: 37-38. AQA-LT. Pr: 0.9713
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNVQSDTNQATPVNSQDKDVANNRGLANSAQNTPNQSATTNQSTNQALVNHNNGSIVNQATPTSVQSSTPSAQNNNHTDGNTTATETVSNANNNDAVSNNTTLNVPNKTNENGSGGHLTLKEIQEDVRHSSDKPELVAIAEPASNRPKKRSRRAAPADPNATPADPGAAAAGNGGAPVAITAPYTPTTDPNANNAGQNAPNEVLSFDDNSIRPSTNRSVPSVTVVDNLPGFTLINGGKVGVLSHAMVRTSMFEAGSNRTYQAQGNVLALGRISGTDASNHGDFNGIEKSLTVNPNSELIFEFNTMTTKNGQGATNVIIKNADTNDTIAEKTVEGGPTLRLFKVPDNVRNLKIQFVPKNDAITDARGIYQLKDGYKYYSFVDSIGLHSGSHVYVERRTMDPTATNNKEFTVTTSLKNNGNSGASLDTNDFVYQVQLPEGVEYVNNSLTKDFPSNNSGVDVNDMNVTYDAANRVITIKSTGGGTANSPARLMPDKILDLRYKLRVNNVPTPRRVTFNETLTYKTYTQDFINSPAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNDLKKRAQTILAENRNNVPLNKRVSQADIDTLTNQMQHTLIRSVDAENAVNQKADQMEDLVNQNDELTDEEKQAAIQVIEEHKGNIIGDIGDQTTDDGVTRIKDQGIQTLSGDTATPVVKPNAKKAIRDKATKQREIINATPDATEDEIQDAINQLATDETDAIDNVTNATTNADVETAKNNGINTIGAVVPQVTHKKAARDAINQATATKRQQINSNREATQEEKNAALNELTQATNHALEQINQATTNADVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDATQEERQAAIDKVNAAVTAANTNILNANTNAEVEQVKTNAIQGIQAITPATKVKTDAKNAIDKSAETQHNTIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGTQNIVVIQPATQVKTDARNVVNDKAREAITNINATPGATREEKQEAINRVNTLKYRALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATTEEKQVALNQVDQELATAINNINQANTNAEVDQAATVAENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAFNQINQNQTNDQVDATTNQAVNAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSLDSTDNEKEVASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANELRAKINQDKEATAEERQVALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDSIALVTPDHIVRAAARDAVKQQYEAKKREIEQAEHATDEEKQVALNQLANNEKRALQNIDQAIANNDVKRVETNGIATLKGVQPHIVIKPEAQQAIKASAENQVESIKDTPHATVDELDEANQLISDTLKQAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSIDAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQNIAIAQVEKELIKAKQQIASAVTNADVAYLLHDEKNEIREIEPVISRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIHDLDVHPIKKPDAEKTINDDLARVTALVQNYRKVSDRNKADALKAITALKLQMDEELKTARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKVKVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEAMKVSPKVIQPAPKVCTPIKKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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