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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA1577 [new locus tag: SA_RS08890 ]
  • pan locus tag?: SAUPAN004438000
  • symbol: SA1577
  • pan gene symbol?: sasC
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA1577 [new locus tag: SA_RS08890 ]
  • symbol: SA1577
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1808960..1815520
  • length: 6561
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    5761
    5821
    5881
    5941
    6001
    6061
    6121
    6181
    6241
    6301
    6361
    6421
    6481
    6541
    ATGAATTTGTTAAAGAAAAATAAATATAGTATTAGGAAGTATAAAGTAGGCATATTCTCT
    ACTTTAATCGGAACAGTTTTATTACTTTCAAACCCAAATGGTGCACAAGCCTTAACTACG
    GATAATAATGTACAAAGCGATACTAATCAAGCCACACCTGTAAATTCACAAGATACAAAT
    GTTGCTAATAATAGAGGTTTAGCAAATAGTGCTCAGAATACACCTAATCAATCTGCAACA
    ACTAATCAATCAACGAATCAAGCATTGGTTAATCATAATAATGGTAGTATAGCAAATCAA
    GCTACGCCAACATCAGTGCAATCAAGTACGCCTTCAGCACAAAACAATAATCATACAGAT
    GGCAATACAACAGCAACTGAGACAGTGTCAAACGCTAATAATAAGGATGTAGTGTCGAAT
    AATACCACATTAAATGTACCTAATAAAACAAATGAAAATGGTTCAGGAGGACATCTAACT
    TTAAAGGAAATTCAAGAAGATGTTCGTCATTCTTCAGATAAACCAGAGCTAGTTGCAATT
    GCTGAACAAGCATCTAATAGACCGAAAAAGAGAAGTAGACGTGCGGCACCGGCAGATCCT
    AATGCAACTCCAGCAGATCCAGCGGCTGCAGCGGCAGGAAACGGTGGTGCACCAGTAGCA
    ATTACAGCGCCATACACGCCGACAACTGATCCTAATGCCAATAATGCAGGACAAAATGCA
    CCTAACGAAGTGCTGTCTTTTGATGACAATGGTATTAGACCAAGTACCAACCGTTCTGTA
    CCATCAGTAACAGTTGTTGATAATTTACCAGGCTTTACACTTATCAATGGTGGTAAAGTA
    GGTGTGTTTAGTCATGCGATGGTTAGAACAAGTATGTTTGATTCAGGAGATGCTAAGAAC
    TATCAAGCACAAGGAAATGTAATTGCATTAGGTCGTATTAAGGGAAATGATACAAATGAT
    CATGGTGATTTTAATGGAATTGAAAAATCTTTAACAGTAAATCCAAATTCTGAATTAATT
    TTCGAATTTAATACGATGACTACAAAAAACTATCAAGGTGTGACAAATTTAATAATTAAA
    AATGCTGATAATGATACTGTTATTGCAGAAAAATCAGTAGCTTATGGTCCGATTTGGCGT
    TTGTTTAAAGTGCCTGAAAATGTTAGTCACTTAAAAATTCAATTTGTACCTAAAAATGAT
    GCAATAACAGATGCGCGTGGCATTTATCAACTAAGAGACGGTTATAAATACTATGACTTT
    GTTGACTCAATTGGTCTACATTCTGGTTCGCATGTCTATGTTGAAAGACGAACAATGGAA
    CCCACAGCTACTAATAATAAAGAATTTACAGTCACAACTTCATTAAAGAATAATGGTAAC
    TTCGGTGCTTCATTTAATACAGATGATTTTGTATATAAAGTTCAATTACCTGAAGGGGTA
    GAATATGTTAATAACTCATTGACTAAAGATTTTCCAAGCAGTAATTCAGGTGTTGATATG
    AATGATTTTAATGTGACGTATGATGCGGCGAATCGAGTGATAACAATTAAAAGTACTGGT
    GGAGGTTCAGGTAACTCGCCGGCACGATTAATGCCTGATAAAATATTGGATTTAAAGTAT
    AAGTTGCGTGTTAATAATGTACCGACACCAAGAACAGTAACATTTAATGATACATTAACA
    TATAAAACATATACACAAGATTTTATTAATTCACCTGCTGAAAGTCATACTGTAAGTACA
    AATCCATATACAATCGATATCATCATGAATAAAGATGCATTACAAGCCGAGGTTGATAGA
    CGCATTCAACAAGCTGATTATACATTTGCATCATTAGATATCTTTAATGATCTTAAAAGA
    CGTGCACAAACGATTTTAGATGAAAATCGTAACAATGTACCATTAAATAAAAGAGTTTCT
    CAAGCAGATATTGATTCATTAACTAATCAAATGCAACATACGTTAATTCGAAGTGTTGAT
    GCTGAAAATGCAGTTAATAAAAAAGTTGACCAAATGGAAGATTTAGTTAATCAAAATGAT
    GAATTGACAGATGAAGAAAAACAAGCAGCAATACAAGTTATCGAGGAACATAAAAATGAA
    ATAATTGGTAATATTGGTGACCAAACGACTGATGATGGCGTTACTAGAATCAAAGATCAA
    GGTATACAGACCTTAAGTGGGGATACTGCAACACCGGTTGTTAAACCAAATGCTAAAAAA
    GCAATACGTGATAAAGCAACGAAACAAAGGGAAATTATCAATGCAACACCAGATGCTACT
    GAAGACGAGATTCAAGATGCACTAAATCAATTAGCTACGGATGAAACAGATGCTATTGAT
    AATGTTACGAATGCTACTACAAATGCTGACGTTGAAATAGCTAAAAATAATGGCATCAAT
    ACTATTGGAGCAGTTGTTCCTCAAGTGACACATAAACAAGCTGCAAGAGATGCAATTAAC
    CAAGCAACAGCAACGAAAAGACAACAAATAAATAGTAATAGAGAAGCAACTCAGGAAGAG
    AAAAATGCAGCATTGAACGAATTAACTCAAGCAACCAACCATGCTTTAGAACAAATCAAT
    CAAGCAACAACAAATGCTGATGTTGATAACGCCAAAGGAGATGGTCTAAATGCCATTAAT
    CCAATTGCTCCTGTAACTGTTGTTAAGCAAGCTGCAAGGGATGCTGTATCACATGATGCA
    CAACAACATATCGCAGAAATCAATGCTAATCCTGATGCGACTCAAGAAGAAAGACAAGCA
    GCAATTGACAAAGTGAATGCTGCTGTAACTGCAGCAAACACAAACATTTTAAACGCTAAT
    ACCAATGCTGATGTTGAACAAGTAAAGACAAATGCGATTCAAGGAATACAAGCAATTACA
    CCAGCTACAAAAGTAAAAACAGATGCAAAAAATGCCATCGATAAAAGTGCGGAAACGCAA
    CATAATACGATATTTAATAATAATGATGCGACGCTCGAAGAACAACAAGCAGCACAACAA
    TTACTTGATCAAGCTGTAGCCACAGCGAAGCAAAATATTAATGCAGCAGATACGAATCAA
    GAAGTTGCACAAGCAAAAGATCAGGGCACACAAAATATAGTTGTGATTCAACCGGCAACA
    CAAGTTAAAACGGATGCTCGCAATGCTGTAAATGATAAAGCTCGAGAGGCGATAACAAAT
    ATCAATGCTACACCTGGCGCGACTCGAGAAGAGAAACAAGAAGCGATAAATCGTGTCAAT
    ACACTTAAAAATAGAGCATTAACTGATATTGGTGTGACGTCTACTACTGCGATGGTCAAT
    AGTATTAGAGACGATGCAGTCAATCAAATCGGCGCAGTTCAACCGCATGTAACGAAGAAA
    CAAACTGCTACAGGTGTATTAAATGATTTAGCAACTGCTAAAAAGCAAGAAATTAATCAA
    AACACAAATGCAACAACTGAAGAAAAGCAAGTGGCTTTAAATCAAGTGGATCAAGAGTTA
    GCAACGGCAATTAATAATATAAATCAAGCTGATACAAATGCGGAAGTAGATCAAGCGCAA
    CAATTAGGTACAAAAGCAATTAATGCGATTCAGCCAAATATTGTTAAAAAACCTGCAGCA
    TTAGCACAAATCAATCAGCATTATAATGCTAAATTAGCTGAAATCAATGCTACACCAGAT
    GCAACGAATGATGAGAAAAATGCTGCGATCAATACTTTAAATCAAGACAGACAACAAGCT
    ATTGAAAGTATTAAACAAGCTAACACAAATGCAGAAGTAGACCAAGCTGCGACAGTAGCA
    GAGAATAATATCGATGCTGTTCAAGTTGATGTAGTAAAAAAACAAGCAGCGCGAGATAAA
    ATCACTGCTGAAGTGGCGAAGCGTATTGAAGCGGTTAAACAAACACCTAATGCAACTGAC
    GAAGAAAAGCAGGCTGCTGTTAATCAAATCAATCAACTTAAAGATCAAGCAATTAATCAA
    ATTAATCAAAACCAAACAAATGATCAGGTAGACACAACTACAAATCAAGCGGTAAATGCT
    ATAGATAATGTTGAAGCTGAAGTAGTAATTAAACCAAAGGCAATTGCAGATATTGAAAAA
    GCTGTTAAAGAAAAGCAACAGCAAATTGATAATAGTCTTGATTCAACAGATAATGAGAAA
    GAAGTTGCTTCACAAGCATTAGCTAAAGAAAAAGAAAAAGCACTTGCAGCTATTGACCAA
    GCTCAAACGAATAGTCAGGTGAATCAAGCAGCAACAAATGGTGTATCAGCGATTAAAATT
    ATTCAACCTGAAACAAAAGTTAAACCAGCTGCACGTGAAAAAATCAATCAAAAAGCGAAT
    GAATTACGTGCTAAGATTAATCAGGATAAAGAAGCAACAGCAGAAGAAAGACAAGTAGCA
    CTAGATAAAATCAATGAATTTGTAAATCAAGCCATGACAGATATTACGAATAATAGAACA
    AATCAACAAGTTGATGATACAACAAGTCAAGCGCTTGATAGCATTGCTTTAGTAGCGCCT
    GAACATATTGTTAGAGCAGCTGCTAGAGATGCAGTAAAGCAACAATATGAGGCTAAAAAG
    CAAGAAATAGAGCAAGCTGAACATGCGACTGATGAAGAAAAACAAGTTGCTTTAAATCAA
    TTAGCGAATAATGAAAAACTTGCATTACAAAACATCAATCAAGCAGTAACGAATAATGAT
    GTGAAACGTGTTGAAACAAATGGCATTGCTACACTAAAAGGTGTACAACCTCATATTGTA
    ATTAAGCCTGAAGCACAACAAGCAATAAAAGCAACTGCAGAAAATCAAGTAGAATCAATA
    AAAGATACACCACATGCAACAGTTGATGAATTAGATGAAGCGAATCAATTAATTAGCGAC
    ACACTCAAACAAGCGCAACAAGAAATAGAAAATACAAATCAAGATGCTGCTGTTACTGAT
    GTTAGAAATCAAACAATCAAGGCAATTGAGCAAATAAAACCTAAAGTAAGACGTAAACGA
    GCTGCGCTTGATAGCATTGAAGAAAATAATAAAAATCAACTCGATGCAATCCGAAATACG
    TTGGATACTACTCAAGATGAAAGAGATGTTGCTATTGATACTTTAAATAAAATTGTAAAT
    ACAATTAAAAATGACATTGCACAAAACAAAACGAATGCAGAAGTGGATCGAACTGAGACT
    GATGGCAACGACAACATCAAAGTGATTTTACCTAAAGTTCAAGTTAAACCAGCAGCGCGT
    CAATCTGTTGGTGTAAAAGCCGAAGCTCAAAATGCACTAATCGATCAAAGCGATTTATCA
    ACTGAAGAAGAAAGACTAGCTGCTAAACATTTAGTAGAACAAGCACTTAATCAGGCTATT
    GATCAGATCAATCATGCAGATAAGACTGCCCAAGTTAATCAAGATAGTATAGATGCTCAA
    AATATTATTTCAAAAATTAAACCAGCGACAACAGTTAAAGCAACAGCATTACAACAAATT
    CAAAATATCGCTACAAATAAAATTAATTTAATTAAAGCAAATAACGAAGCGACAGATGAA
    GAACAAAATATTGCAATAGCACAAGTTGAAAAAGAGTTAATTAAAGCTAAACAACAAATT
    GCTAGTGCAGTGACTAATGCTGATGTGGCATATTTATTGCATGATGAGAAAAACGAAATT
    CGTGAAATCGAACCTGTTATTAACAGAAAGGCGTCTGCTCGAGAACAATTGACAACATTA
    TTCAACGATAAAAAACAAGCAATTGAAGCGAATATTCAAGCAACGGTAGAAGAAAGAAAT
    AGTATATTAGCACAGTTACAAAATATTTATGACACTGCTATTGGACAAATTGATCAAGAT
    CGTAGCAATGCACAAGTTGATAAAACAGCATCATTAAATCTACAAACAATACATGATTTA
    GATGTACATCCTATTAAAAAGCCAGATGCTGAAAAAACGATTAATGATGATCTTGCACGC
    GTCACTGCTTTAGTGCAAAATTATCGAAAAGTAAGTAATCGTAATAAGGCTGATGCATTA
    AAAGCTATAACTGCTTTAAAATTACAAATGGATGAAGAATTAAAAACAGCACGCACTAAT
    GCTGATGTTGATGCAGTTTTAAAACGATTTAATGTTGCATTAAGCGATATAGAAGCAGTA
    ATTACTGAAAAAGAAAATAGCTTACTGCGAATTGATAACATTGCTCAACAAACATATGCG
    AAATTCAAAGCGATCGCAACACCAGAACAATTAGCTAAAGTAAAAGTATTAATTGATCAA
    TATGTTGCAGATGGCAATAGAATGATTGATGAAGATGCGACATTAAATGACATCAAACAA
    CACACGCAATTCATTGTTGATGAAATTTTAGCAATTAAATTACCAGCTGAAGCGACGAAA
    GTATCACCAAAAGAAATTCAGCCAGCTCCAAAAGTTTGTACGCCTATTAAAAAAGAAGAG
    ACACATGAATCGCGCAAAGTTGAAAAAGAACTTCCAAATACAGGTTCTGAAGGAATGGAT
    TTACCATTGAAAGAATTTGCACTGATTACAGGTGCGGCTTTGTTAGCTAGAAGACGTACT
    AAAAACGAAAAAGAATCATAA
    60
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    6300
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    6420
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    6540
    6561

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA1577 [new locus tag: SA_RS08890 ]
  • symbol: SA1577
  • description: hypothetical protein
  • length: 2186
  • theoretical pI: 4.91259
  • theoretical MW: 238448
  • GRAVY: -0.667566

⊟Function[edit | edit source]

  • TIGRFAM:
    SasC/Mrp/FmtB intercellular aggregation domain (TIGR04263; HMM-score: 420.7)
    and 2 more
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 34.9)
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 17.3)
  • TheSEED  :
    • Predicted cell-wall-anchored protein SasC (LPXTG motif)
    Virulence, Disease and Defense Adhesion Adhesins in Staphylococcus  Predicted cell-wall-anchored protein SasC (LPXTG motif)
  • PFAM:
    B_GA (CL0598) DUF1542; Domain of Unknown Function (DUF1542) (PF07564; HMM-score: 895.7)
    and 2 more
    no clan defined YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 40.8)
    ATP-synt_E_2; ATP synthase epsilon subunit (PF08112; HMM-score: 7.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 0
  • LocateP: LPxTG Cell-wall anchored
    • Prediction by SwissProt Classification: Cell Wall
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: -0.17
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: found LPxTG motif :LPNTG
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.992842
    • TAT(Tat/SPI): 0.003081
    • LIPO(Sec/SPII): 0.000849
    • Cleavage Site: CS pos: 37-38. AQA-LT. Pr: 0.9718
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNVQSDTNQATPVNSQDTNVANNRGLANSAQNTPNQSATTNQSTNQALVNHNNGSIANQATPTSVQSSTPSAQNNNHTDGNTTATETVSNANNKDVVSNNTTLNVPNKTNENGSGGHLTLKEIQEDVRHSSDKPELVAIAEQASNRPKKRSRRAAPADPNATPADPAAAAAGNGGAPVAITAPYTPTTDPNANNAGQNAPNEVLSFDDNGIRPSTNRSVPSVTVVDNLPGFTLINGGKVGVFSHAMVRTSMFDSGDAKNYQAQGNVIALGRIKGNDTNDHGDFNGIEKSLTVNPNSELIFEFNTMTTKNYQGVTNLIIKNADNDTVIAEKSVAYGPIWRLFKVPENVSHLKIQFVPKNDAITDARGIYQLRDGYKYYDFVDSIGLHSGSHVYVERRTMEPTATNNKEFTVTTSLKNNGNFGASFNTDDFVYKVQLPEGVEYVNNSLTKDFPSSNSGVDMNDFNVTYDAANRVITIKSTGGGSGNSPARLMPDKILDLKYKLRVNNVPTPRTVTFNDTLTYKTYTQDFINSPAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNDLKRRAQTILDENRNNVPLNKRVSQADIDSLTNQMQHTLIRSVDAENAVNKKVDQMEDLVNQNDELTDEEKQAAIQVIEEHKNEIIGNIGDQTTDDGVTRIKDQGIQTLSGDTATPVVKPNAKKAIRDKATKQREIINATPDATEDEIQDALNQLATDETDAIDNVTNATTNADVEIAKNNGINTIGAVVPQVTHKQAARDAINQATATKRQQINSNREATQEEKNAALNELTQATNHALEQINQATTNADVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDATQEERQAAIDKVNAAVTAANTNILNANTNADVEQVKTNAIQGIQAITPATKVKTDAKNAIDKSAETQHNTIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGTQNIVVIQPATQVKTDARNAVNDKAREAITNINATPGATREEKQEAINRVNTLKNRALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATTEEKQVALNQVDQELATAINNINQADTNAEVDQAQQLGTKAINAIQPNIVKKPAALAQINQHYNAKLAEINATPDATNDEKNAAINTLNQDRQQAIESIKQANTNAEVDQAATVAENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAINQINQNQTNDQVDTTTNQAVNAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSLDSTDNEKEVASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANELRAKINQDKEATAEERQVALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDSIALVAPEHIVRAAARDAVKQQYEAKKQEIEQAEHATDEEKQVALNQLANNEKLALQNINQAVTNNDVKRVETNGIATLKGVQPHIVIKPEAQQAIKATAENQVESIKDTPHATVDELDEANQLISDTLKQAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSIDAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQNIAIAQVEKELIKAKQQIASAVTNADVAYLLHDEKNEIREIEPVINRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIHDLDVHPIKKPDAEKTINDDLARVTALVQNYRKVSNRNKADALKAITALKLQMDEELKTARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKVKVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEATKVSPKEIQPAPKVCTPIKKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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