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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002480
  • pan locus tag?: SAUPAN006098000
  • symbol: fnbA
  • pan gene symbol?: fnbA
  • synonym:
  • product: fibronectin-binding protein FnbA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002480
  • symbol: fnbA
  • product: fibronectin-binding protein FnbA
  • replicon: chromosome
  • strand: -
  • coordinates: 2483480..2486569
  • length: 3090
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    GTGAAAAACAATCTTAGGTACGGCATTAGAAAACATAAATTGGGAGCAGCATCAGTATTC
    TTAGGAACAATGATCGTTGTTGGGATGGGACAAGATAAAGAAGCTGCAGCATCAGAACAA
    AAGACAACTACAGTAGAAGAAAATGGGAATTCAGCTACTGATAATAAAGTAAACGAAACA
    CAAACAACTACAACTAACGTTAATACTATAGATGAAACACAATCATACAGCGCAACAGCA
    ACAGAACAACCGTCAAACGCAACACAAGTAACAACTGAAAAAGCACCAAAAGCAGTACAA
    GCACCACAAACTGCACAACCAGCAAATGTAGAAACAGTTAAAGAAGAGGTAGTTAAGGAA
    GAAGCGAACCCTCAAGTTAAGGAAACGACACAATCTCAAGACAATAGCGGAGATCAAAGA
    CAAGTAGATTTAACACCTAAAAAGGCTACACAAAATCAAGCAGCAGAAACACAAGTTGAA
    GTGGCACAGCCAAGAACGGTATCAGAAAGTAAACCACGTGTGACAAGATCAGCAGATGTA
    GCGGAAGCTAAGGAAGCTAGTGACGCGAAAGTGGAAACGGGTACAGATGTGACAAGTAAA
    GTTACAGTGGAAAGTGGTTCTATTGAGGCACCTCAAGGAAATAAAGTAGAGCCACATGCT
    GGTCAACGTGTCGTACTGAAATACAAATTGAAATTCGAAAAGGGTTTACACAAAGGAGAT
    TATTTTGATTTCACCTTGTCTAATAATGTAAATACTTATGGAGTTTCAACAGCTAGAAAA
    GTACCAGAAATCAAAAATGGTTCAGTCGTAATGGCGACAGGTCAACTTCTTGGAAATGGG
    AAAATTAGGTATACATTTACAGACTATATTGATTATAAAGTAAATGTGACTGCTGATTTA
    GAAATCAATTTATTTATTGATCCTAAAACTGTACAAAGCAATGGACAACAAACAATAACT
    TCAACGTTGAATGATAAGGAAACAAAAAACACATTGCCAATAGAATATAATCCAGGAGTA
    AGTAATAGCTATGCTAATGTAAATGGATCTATTGAAACTTTTGATAAAGGGAACAATAAA
    TTCACTCATGTAGCTTACATAAAACCACAAAATGGGCATAAATCAGATAGCGTTTCAATT
    ACTGGTACACTAACTCAAGGTAGCAAAGCTAATGGAAATGTTCCAACTGTAAAAGTATAT
    GAAGTCTTAAAGGATGCTAAAGAATTACCAGAAAGTGTATATGCAAACATATCAGACTCT
    ACAATGTTTAAAGATGTAACTCAGGAAATGAAAGATAAATTAAAAGTAGAAAATAATGGG
    AGTTATAAATTAGACATTGAGAAATTAGAAAAAAGTTATGTTATACACTATGATGGTGAA
    TACTTAAGTGGTTCAGATCAAGTGAATTTTAGAACGCATATGTTTGGATATCCAGAACAG
    CAGTATAAGTACTACTATACTCATTTGGGATACCAACTTACATGGGATAATGGATTAGTT
    TTATATAGTAACAAAGCAAAAGGTGATGGAACGAATGGAACAATAACAGAATCGAATAAT
    ATGACATTTGATGAAGAATATGGAACTGGAGTTATTACAGGTCAATATGATAAGAATTTA
    GTAACTACTGTTGAAGAAGAATATGATTCTTCAACTCTTGACATTGATTACCACACAGCT
    ATAGATGGTGAAGGTGGTTATGTTGATGGATACATTGAAACAATAGAAGAAACGGATTCA
    TCAGCTATTGATATCGATTACCATACTGCTGTGGATAGCGAAGCGGGTCACGTTGGAGGA
    TACACTGAGTCCTCTGAGGAATCAAATCCAATTGACTTTGAAGAATCTACGCATGAAAAT
    TCAAAACATCACGCTGATGTTGTTGAATATGAAGAGGATACAAACCCAGGTGGTGGTCAG
    GTTACTACTGAGTCTAACTTAGTTGAATTTGACGAAGAGTCTACAAAAGGTATTGTAACT
    GGCGCAGTGAGCGACCATACAACAATTGAAGATACGAAAGAATATACAACTGAAAGTAAT
    CTGATTGAACTAGTAGATGAACTACCTGAAGAACATGGTCAAGCACAAGGACCAATCGAG
    GAAATTACTGAAAACAATCATCATATTTCTCATTCTGGTTTAGGAACTGAAAATGGTCAC
    GGTAATTATGGTGTGATTGAAGAAATCGAAGAAAATAGCCATGTTGATATTAAGAGTGAA
    TTAGGTTATGAAGGTGGCCAAAATAGCGGTAACCAGTCATTCGAGGAAGACACAGAAGAA
    GATAAACCTAAATATGAACAAGGTGGCAATATCGTAGATATCGATTTCGATAGTGTACCT
    CAAATTCATGGTCAAAATAAAGGTGATCAGTCATTCGAAGAAGATACAGAGAAAGACAAA
    CCTAAGTATGAACAAGGTGGTAATATCATTGATATCGACTTCGACAGTGTGCCACAAATT
    CATGGATTCAATAAGCATAATGAAATTATTGAAGAAGATACAAACAAAGATAAACCAAAT
    TATCAATTCGGTGGACACAACATTGTTGATTTTGAAGAAGATACACTTCCGAAAGTAAGC
    GGTCAAAATGAAGGTCAACAAACGATTGAAGAAGATACAACGCCGCCAACGCCACCGACA
    CCAGAAGTACCGAGTGAGCCGGAAACACCAACACCACCGACGCCGGAAGTACCGAGTGAG
    CCAGAAACACCAACGCCACCGACACCAGAAGTACCAAGTGAGCCGGAAACACCAACACCG
    CCAACACCAGAGGTACCAAGTGAGCCGGAAACACCAACACCGCCAACACCAGAGGTACCA
    GCTGAACCTGGTAAACCAGTACCACCTGCTAAAGAAGAACCTAAAAAACCTTCTAAACCA
    GTGGAACAAGGTAAAGTAGTAACACCTGTTATTGAAATCAATGAAAAGGTTAAAGCAGTG
    GCACCAACTAAACAAAAACAATCTAAGAAATCTGAACTACCTGAAACAGGTGGAGAAGAA
    TCAACAAACAAAGGTATGTTGTTCGGCGGATTATTCAGCATTCTAGGTTTAGCGTTATTA
    CGTAGAAATAAAAAGAATAACAAAGCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
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    1680
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    1920
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    2160
    2220
    2280
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    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3090

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002480
  • symbol: FnbA
  • description: fibronectin-binding protein FnbA
  • length: 1029
  • theoretical pI: 4.2863
  • theoretical MW: 112762
  • GRAVY: -0.907386

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 25.1)
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 22)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Adhesin (CL0204) SdrG_C_C; C-terminus of bacterial fibrinogen-binding adhesin (PF10425; HMM-score: 122.2)
    no clan defined Fn_bind; Fibronectin binding repeat (PF02986; HMM-score: 112.7)
    and 3 more
    E-set (CL0159) Big_8; Bacterial Ig domain (PF17961; HMM-score: 83.7)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 36.1)
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 35)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 0
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cell wall & surface Score: 0.9513
    • Extracellular Score: 0.0487
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.883257
    • TAT(Tat/SPI): 0.008237
    • LIPO(Sec/SPII): 0.093264
    • Cleavage Site: CS pos: 37-38. AAA-SE. Pr: 0.7428
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKNNLRYGIRKHKLGAASVFLGTMIVVGMGQDKEAAASEQKTTTVEENGNSATDNKVNETQTTTTNVNTIDETQSYSATATEQPSNATQVTTEKAPKAVQAPQTAQPANVETVKEEVVKEEANPQVKETTQSQDNSGDQRQVDLTPKKATQNQAAETQVEVAQPRTVSESKPRVTRSADVAEAKEASDAKVETGTDVTSKVTVESGSIEAPQGNKVEPHAGQRVVLKYKLKFEKGLHKGDYFDFTLSNNVNTYGVSTARKVPEIKNGSVVMATGQLLGNGKIRYTFTDYIDYKVNVTADLEINLFIDPKTVQSNGQQTITSTLNDKETKNTLPIEYNPGVSNSYANVNGSIETFDKGNNKFTHVAYIKPQNGHKSDSVSITGTLTQGSKANGNVPTVKVYEVLKDAKELPESVYANISDSTMFKDVTQEMKDKLKVENNGSYKLDIEKLEKSYVIHYDGEYLSGSDQVNFRTHMFGYPEQQYKYYYTHLGYQLTWDNGLVLYSNKAKGDGTNGTITESNNMTFDEEYGTGVITGQYDKNLVTTVEEEYDSSTLDIDYHTAIDGEGGYVDGYIETIEETDSSAIDIDYHTAVDSEAGHVGGYTESSEESNPIDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQNKGDQSFEEDTEKDKPKYEQGGNIIDIDFDSVPQIHGFNKHNEIIEEDTNKDKPNYQFGGHNIVDFEEDTLPKVSGQNEGQQTIEEDTTPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKQKQSKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNNKA

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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