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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_0375 [new locus tag: NWMN_RS02125 ]
  • pan locus tag?: SAUPAN001990000
  • symbol: NWMN_0375
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_0375 [new locus tag: NWMN_RS02125 ]
  • symbol: NWMN_0375
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 423268..424224
  • length: 957
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTTAACTAAAGAATTTGCACAACGCGTAGAACTAAGTGAGAAGCAAGTACGTAAAATT
    GTTCAACATTTAGAAGAACGTGGTTACCAACTAAGCAAGACTGAATATCGTGGTCGTGAA
    GCAACTGATTTCAAAGAAGAAGATATCGAGCTTTTCAAAGACATTGCCGACAAAGTAAAA
    CAAACAAATAGTTATGATCTAGCGTTTGATGAATTAGAAAAAGAAAAAGACTTCCTGCAA
    GTCATTGTCAAAAACGATGACAAAAACTTACCTACTAATCAAAATGTCGCTCAACTAGTA
    GAAGATTTACGCCTAGAAATCCAGAAAATGCGCGAAGAACGTCACCTACTTGGTCAAATG
    ATGAATCAAGTACATCAGCAACAACAAGAATTAAAAGAACTTCAAAATCAACTTACATCT
    AAAATCGATTCAAATAGCGAATCCTTAAAAGCCATCCAAACATCACAAGAGGCTATCCAA
    GAAGCGCAAGCCTCTCAAGCAAAAGCATTAGCTGAATCAACAAATAAAGTTGAAAAGAAT
    GCTGTTACTGAAGATAAAGCTGACAGTAAAGATTCGAAGGTTGCTGGAGTGAATACATCA
    ACAGACGCTAAGACGGATACTAAAGCAGAAAATGCAGGCGATGGCACTGCTACTAATGTA
    GATAAAGAGGATCAAATTTCTGCAACTGAAGCAATTGAAAAAGCCAGCGTTGAGCAGTCT
    AAAAATGACAATGCAGCTGAGACTTCAAATAAAGAAGCTACAGTAGATGCAGAAGCGCAA
    CATGATGCTGAACAACAAGTAGCAGAAGCCCATGCAGAAGCTTCTAAACAAGCTACTTCG
    AACGATTCATTGGAAGCGAAAGCAGAAAATGACAGCACAGCTTCACAGTCAGAAATGTCA
    GAACCAAAACCTCAAGAAGAGAAAAAAGGTTTCTTCGCACGTTTATTCAACCTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    957

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_0375 [new locus tag: NWMN_RS02125 ]
  • symbol: NWMN_0375
  • description: hypothetical protein
  • length: 318
  • theoretical pI: 4.42803
  • theoretical MW: 35597.6
  • GRAVY: -1.05

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA excision repair protein (rad2) (TIGR00600; HMM-score: 4)
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 3.6)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 3.6)
    and 1 more
    Metabolism Transport and binding proteins Cations and iron carrying compounds K+-dependent Na+/Ca+ exchanger (TIGR00927; HMM-score: 2.8)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined Med9; RNA polymerase II transcription mediator complex subunit 9 (PF07544; HMM-score: 16.9)
    SbcD_C; Type 5 capsule protein repressor C-terminal domain (PF12320; HMM-score: 15.2)
    HTH (CL0123) HTH_36; Helix-turn-helix domain (PF13730; HMM-score: 15.2)
    and 1 more
    no clan defined Snapin_Pallidin; Snapin/Pallidin (PF14712; HMM-score: 7.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003324
    • TAT(Tat/SPI): 0.000347
    • LIPO(Sec/SPII): 0.000788
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATNVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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