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NCBI: 06-JUL-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_1205 [new locus tag: NWMN_RS06780 ]
- pan locus tag?: SAUPAN003607000
- symbol: mutL
- pan gene symbol?: mutL
- synonym:
- product: DNA mismatch repair protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_1205 [new locus tag: NWMN_RS06780 ]
- symbol: mutL
- product: DNA mismatch repair protein
- replicon: chromosome
- strand: +
- coordinates: 1329268..1331277
- length: 2010
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 5332184 NCBI
- RefSeq: YP_001332239 NCBI
- BioCyc:
- MicrobesOnline: 3706757 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1981ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTA
GTTGAAAGACCGAGTTCTGTTGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCT
ACAGAAATAAGCATTGAAGTAGAGGAATCTGGCGTCCAATCTATTCGCGTAGTCGATAAT
GGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGACATGCGACTAGTAAA
TTAGATCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTA
GCCAGTATTTCATCAGTTGCTAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGA
AATGAAATATATGTAGAAAATGGTGAAATATTAAATCATAAGCCTGCAAAAGCGAAAAAA
GGAACAGATATACTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATT
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAACAGAATGGCAATGAGC
CATCCGGACATTCGAATAGCACTCATTTCAGATGGCAAAACAATGTTAAGTACAAATGGT
TCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGATGAAAGTTGCACGAGATTTA
GTACATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAAC
TTTATGCTAAATAAAGCGATTTTAGAAGGCTATCATACACTCTTAACAATAGGTAGGTTC
CCGATTTGTTATATTAATATTGAAATGGATCCAATCTTAGTAGACGTAAATGTTCATCCA
ACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATACCAATTGATTGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCA
AAAAAAAATAAAGTATTACATTCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAA
AACACAGAGAATAACCAAGAGAAGACGTTTTCATCTGAAGAAAGTAACAGTAAGCCATTT
ATGGAAGAAAATCAAAACGATGAGATAGTTATAAAAGAAGATTCATATAATCCATTCGTA
ACGAAAACATCTGAAAGTTTAATAGCTGATGATGAATCTTCTGGTTATAATAATACACGT
GAAAAAGATGAAGACTACTTCAAAAAACAACAAGAAATTTTACAAGAAATGGATCAAACA
TTTGATTCAAATGATGGTACAACTGTGCAAAATTATGAGAATAAAGCGTCTGATGATTAT
TATGATGTAAACGATATTAAAGGAACAAAAAGTAAAGACCCTAAACGAAGAATTCCATAT
ATGGAAATTGTTGGACAAGTACATGGAACGTATATTATTGCTCAAAATGAATTTGGCATG
TACATGATTGACCAGCATGCAGCTCAAGAAAGAATAAAATATGAATATTTTCGAGATAAA
ATAGGTGAGGTTACCAATGAAGTACAAGATTTATTAATCCCGTTAACATTTCATTTTTCA
AAAGATGAACAATTAGTCATTGATCAATATAAAAATGAGCTTCAACAAGTAGGTATCATG
TTAGAACATTTTGGTGGTCATGATTATATTGTAAGTAGCTATCCAGTTTGGTTCCCTAAA
GATGAAGTAGAAGAAATTATTAAAGATATGATTGAGCTAATTTTGGAAGAGAAAAAAGTA
GATATCAAAAAATTACGTGAAGATGTAGCAATCATGATGTCATGTAAAAAATCCATTAAA
GCGAATCATTATTTACAAAAACATGAAATGTCTGATTTAATTGATCAATTAAGAGAAGCG
GAAGATCCATTTACATGTCCACATGGTCGTCCAATAATCATTAATTTTTCAAAATACGAA
TTAGAAAAATTATTTAAGCGTGTGATGTAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_1205 [new locus tag: NWMN_RS06780 ]
- symbol: MutL
- description: DNA mismatch repair protein
- length: 669
- theoretical pI: 5.05367
- theoretical MW: 76854.5
- GRAVY: -0.538715
⊟Function[edit | edit source]
- ⊞TIGRFAM: DNA metabolism DNA replication, recombination, and repair DNA mismatch repair protein MutL (TIGR00585; HMM-score: 338.9)and 4 more
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- ⊞PFAM: no clan defined MutL_C; MutL C terminal dimerisation domain (PF08676; HMM-score: 157.2)S5 (CL0329) DNA_mis_repair; DNA mismatch repair protein, C-terminal domain (PF01119; HMM-score: 130.2)and 3 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSKLDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYIKSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPEHSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSKIQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQNTENNQEKTFSSEESNSKPFMEENQNDEIVIKEDSYNPFVTKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNDGTTVQNYENKASDDYYDVNDIKGTKSKDPKRRIPYMEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIMLEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREAEDPFTCPHGRPIIINFSKYELEKLFKRVM
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: mutS > mutL > glpP
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available