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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1940 [new locus tag: NWMN_RS11190 ]
  • pan locus tag?: SAUPAN005268000
  • symbol: sdrH
  • pan gene symbol?: sdrH
  • synonym:
  • product: SdrH protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_1940 [new locus tag: NWMN_RS11190 ]
  • symbol: sdrH
  • product: SdrH protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2147326..2148597
  • length: 1272
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    GTGTCTCGTGAAATGTCATATCATTGGTTTAAGAAAATGTTACTTTCAACAAGTATTTTA
    ATTTTAAGTAGTAGTAGTTTAGGGCTTGCAACGCACACAGTTGAAGCAAAGGATAACTTA
    AATGGAGAAAAACCAACTACTAATTTGAATCATAATATAACTTCACCATCAGTAAATAGT
    GAAATGAATAATAATGAGACTGGGACACCTCACGAATCAAATCAAACGGGTAATGAAGGA
    ACAGGTTCGAATAGTCGTGATGCTAATCCTGATTCGAATAATGTGAAGCCAGACTCAAAC
    AACCAAAACCCAAGTACAGATTCAAAACCAGACCCAAATAACCAAAACCCAAGTCCGAAT
    CCTAAACCAGATCCAGATAACCCGAAACCAAAACCGGATCCAAAACCAGACCCAGATAAA
    CCAAAGCCAAATCCGGATCCAAAACCAGATCCAGATAACCCGAAACCAAATCCAGATCCA
    AAACCAGACCCAGATAAACCAAAGCCAAATCCGGATCCAAAACCAGATCCAGATAAACCA
    AAGCCAAATCCGAATCCAAAACCAGACCCTAATAAGCCAAATCCTAACCCGTCACCAGAT
    CCCGATCAACCTGGGGATTCCAATCATTCTGGTGGCTCGAAAAATGGGGGGACATGGAAC
    CCAAATGCTTCAGATGGATCTAATCAAGGTCAATGGCAACCAAATGGGAATCAAGGAAAC
    TCACAAAATCCTACTGGTAATGATTTTGTATCCCAACGATTTTTAGCCTTGGCAAATGGG
    GCTTACAAGTATAATCCGTATATTTTAAATCAAATTAATAAGTTGGGCAAAGATTATGGA
    GAAGTTACTGATGAAGACATTTATAATATTATTCGAAAACAAAATTTCAGCGGAAATGCA
    TATTTAAATGGATTACAACAGCAATCGAATTACTTTAGATTCCAATATTTCAATCCATTG
    AAATCAGAAAGGTACTATCGTAATTTAGATGAACAAGTACTCGCATTAATTACTGGTGAA
    ATTGGATCAATGCCAGATTTGAAAAAGCCCGAAGATAAGCCGGATTCAAAACAACGCTCA
    TTTGAACCGCATGAAAAAGACGATTTTACAGTAGTTAAAAAACAAGAAGATAATAAGAAA
    AGTGCGTCAACTGCATATAGTAAAAGTTGGCTAGCAATTGTATGTTCTATGATGGTGGTA
    TTTTCAATCATGCTATTCTTATTTGTAAAGCGAAATAAAAAGAAAAATAAAAACGAATCA
    CAGCGACGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1272

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_1940 [new locus tag: NWMN_RS11190 ]
  • symbol: SdrH
  • description: SdrH protein
  • length: 423
  • theoretical pI: 8.32549
  • theoretical MW: 47133.3
  • GRAVY: -1.40804

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined Orf78; Orf78 (ac78) (PF06024; HMM-score: 15.9)
    and 4 more
    COX2-transmemb; Cytochrome C oxidase subunit II, transmembrane (PF09125; HMM-score: 11.7)
    Internalin_N; Bacterial adhesion/invasion protein N terminal (PF12354; HMM-score: 11)
    Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 6.4)
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 6.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helices: 2
  • LocateP: C-terminally anchored (with CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: -2
    • Predicted Cleavage Site: HTVEAKDN
  • SignalP: Signal peptide SP(Sec/SPI) length 36 aa
    • SP(Sec/SPI): 0.948098
    • TAT(Tat/SPI): 0.046929
    • LIPO(Sec/SPII): 0.003282
    • Cleavage Site: CS pos: 36-37. VEA-KD. Pr: 0.9528
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSREMSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDNPKPNPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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