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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2157 [new locus tag: NWMN_RS12455 ]
  • pan locus tag?: SAUPAN005708000
  • symbol: NWMN_2157
  • pan gene symbol?: —
  • synonym:
  • product: GCN5-related N-acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2157 [new locus tag: NWMN_RS12455 ]
  • symbol: NWMN_2157
  • product: GCN5-related N-acetyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 2380574..2381461
  • length: 888
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAGCATAGTTCAGTTATATGATATTACACAAATAAAATCGTTCATTGAACATTCGAAT
    TATGAATCAGCATCATACTTATATAAACTTCCTCAACAGTACAATGAAATAGATGTATTA
    ATAACCGATGCGATTGAATCACCTGGTGTATTTTCGATTAAAGAAAACGATTCAATCAAA
    GCAATCATATTGTCTTTTGCATACGATAAAAATAAATTCAAAGTCATAGGCCCTTTCGTG
    GCTGACAATTATGTATTATCTGTCGATACGTTTGAAACGCTATTTAAAGCAATGACTTCG
    AACCAACCTGACGATGCCGTCTTTAACTTTTCTTTTGAAGAAGGCATTCAACAATACAAA
    CCATTAATGAAAGTTATTCAAGCAAGTTATAACTTCACTGACTATTACATAGAAGCCCGT
    ACAAGATTAGAAGAAGATATGCACCAACCAAATATCATTCCTTATCACAAAGGGTTTTAT
    CGTGCTTTCAGCAAATTACACACAACTACATTTAAATATCAGGCACAGTCACCACAAGAT
    ATCATTGATAGTTTAGACGACCATCATCATTTGTTTTTATTTGTTAGCGAAGGTTTACTT
    AAAGGTTATTTATACCTTGAAATTGATTCACAACAGTCAATCGCCGAGATTAAATACTTC
    AGTTCTCATGTAGATTACCGTTTGAAAGGTATCGCTTTCGAGTTGCTTGCGTATGCATTG
    CAATATGCTTTTGATAATTTTGATATTAGAAAAGTTTATTTTAAAATTCGTAATAAAAAT
    AATAAACTCATCGAACGATTTAATGGTCTAGGTTTCCATATCAACTATGAGTACATTAAA
    TTCAAATTCGAATCACGTAACGTAAAAGATCAAACAATCCCTGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    888

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_2157 [new locus tag: NWMN_RS12455 ]
  • symbol: NWMN_2157
  • description: GCN5-related N-acetyltransferase
  • length: 295
  • theoretical pI: 5.82928
  • theoretical MW: 34763.1
  • GRAVY: -0.32983

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 22.9)
    UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 20)
    and 1 more
    colanic acid biosynthesis protein WcaM (TIGR04004; HMM-score: 14.1)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 30.9)
    and 3 more
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 24)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 19.7)
    Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002383
    • TAT(Tat/SPI): 0.000091
    • LIPO(Sec/SPII): 0.00026
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSIVQLYDITQIKSFIEHSNYESASYLYKLPQQYNEIDVLITDAIESPGVFSIKENDSIKAIILSFAYDKNKFKVIGPFVADNYVLSVDTFETLFKAMTSNQPDDAVFNFSFEEGIQQYKPLMKVIQASYNFTDYYIEARTRLEEDMHQPNIIPYHKGFYRAFSKLHTTTFKYQAQSPQDIIDSLDDHHHLFLFVSEGLLKGYLYLEIDSQQSIAEIKYFSSHVDYRLKGIAFELLAYALQYAFDNFDIRKVYFKIRNKNNKLIERFNGLGFHINYEYIKFKFESRNVKDQTIPE

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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