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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS03725 [old locus tag: NWMN_0657 ]
  • pan locus tag?: SAUPAN002572000
  • symbol: NWMN_RS03725
  • pan gene symbol?:
  • synonym:
  • product: aldo/keto reductase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS03725 [old locus tag: NWMN_0657 ]
  • symbol: NWMN_RS03725
  • product: aldo/keto reductase
  • replicon: chromosome
  • strand: +
  • coordinates: 738456..739364
  • length: 909
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (738456..739364) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0657

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGAACAAATAATGATTAATCACTATGTTCATTTTTCTAGGCTTGTACAAGGTTTTTGG
    CGTGCAAATGAATGGAAGATGACTGCGAAAGAGTTAAATTATTTTATAAATGAATTAGTT
    GAACGTGGAATTACAACGATGGATCATGCTGATATTTATGGAGATTATCAATGTGAATCA
    CTGTTTGGTAATGCTTTGGATTTATCACCCGAATTAAGAAATAAAATTCAAATTGTTACG
    AAATGTGGTATCATTTTGCCTTCTAAGCAATTTGATTTTACAAATGGACATCGTTATGAT
    TTGAGTAGTAAGCACATCGTGAAATCTGTTGAACAGTCATTAATCAATTTGAATGTAGAT
    TATTTAGATAGTCTACTCATTCATCGTCCTTCACCATTGATGGATCCAGAACAAGTTGCT
    GATGCATTAACTAAACTTGTTAAACAAGGTAAGTTGAAGTCATTCGGGGTGTCGAATTTT
    AATCATTCACAATACCAATTGTTAAATCAATATATTATGAAAGAAAGACTACATATTAGC
    ATCAATCAATTAGAATTATCGCCATATCACGTTGATAGTTTACAAGATGGAACAATGGAT
    TCAATGTATCAAAACCATGTTCAAATCATGGCTTGGAGTCCTTTTGCAGGCGGTAAAATT
    TTCGACAAGGAAGATATTAAAGCGCAACGTATTATGAAAGTTGTTCAATCAATAGCTGAC
    AAATATGGTGTGAGTGACACAGCTGTGATGATAGCGTGGTTAGTAAAAATACCGCATCGT
    ATCATGCCGATACTTGGAACAAGTCAGTTAAAGCGTATTGATCAAGCAATCGAAGGGCTA
    CAACTTAATTTAGATGATCAGTCGTGGTTTGACATTTACACCGCTATTATCGGACAAGAT
    ATTCCGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    909

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS03725 [old locus tag: NWMN_0657 ]
  • symbol: NWMN_RS03725
  • description: aldo/keto reductase
  • length: 302
  • theoretical pI: 6.43632
  • theoretical MW: 34776.8
  • GRAVY: -0.227815

Function[edit | edit source]

  • TIGRFAM:
    voltage-dependent potassium channel beta subunit (TIGR01293; HMM-score: 70.2)
    and 1 more
    Metabolism Central intermediary metabolism Polyamine biosynthesis carboxynorspermidine decarboxylase (TIGR01047; HMM-score: 13.7)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined Aldo_ket_red; Aldo/keto reductase family (PF00248; HMM-score: 192.4)
    and 2 more
    YqgF (CL0580) YqgF; Holliday-junction resolvase-like of SPT6 (PF14639; HMM-score: 12.5)
    HTH (CL0123) SelB-wing_2; Elongation factor SelB, winged helix (PF09106; HMM-score: 11.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005208
    • TAT(Tat/SPI): 0.000211
    • LIPO(Sec/SPII): 0.000612
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MEQIMINHYVHFSRLVQGFWRANEWKMTAKELNYFINELVERGITTMDHADIYGDYQCESLFGNALDLSPELRNKIQIVTKCGIILPSKQFDFTNGHRYDLSSKHIVKSVEQSLINLNVDYLDSLLIHRPSPLMDPEQVADALTKLVKQGKLKSFGVSNFNHSQYQLLNQYIMKERLHISINQLELSPYHVDSLQDGTMDSMYQNHVQIMAWSPFAGGKIFDKEDIKAQRIMKVVQSIADKYGVSDTAVMIAWLVKIPHRIMPILGTSQLKRIDQAIEGLQLNLDDQSWFDIYTAIIGQDIP

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]