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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS04070 [old locus tag: NWMN_0720 ]
  • pan locus tag?: SAUPAN002660000
  • symbol: NWMN_RS04070
  • pan gene symbol?: comFC
  • synonym:
  • product: competence protein ComF

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS04070 [old locus tag: NWMN_0720 ]
  • symbol: NWMN_RS04070
  • product: competence protein ComF
  • replicon: chromosome
  • strand: +
  • coordinates: 806184..806858
  • length: 675
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (806184..806858) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0720

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAATAATTGTTTGAGTTGTGGTGCTAAGTTATATGAAAATATAACCATTTATAATTTG
    TTCAAGAAACCTAATAGATTATGTGACAGATGCAAAGAGAATTGGGACAATATTAAACTT
    GATATTAAAGCAAGGCGATGTTCAAGGTGCTTAAAACACTTAAATCAAGATGAAGCGTAT
    TGTTTAGACTGCAAGTTTCTATCGGCACACTTTAATTTAATGGAACAATTATATTGTCAA
    TTTCAATATGACGGTTTAATGAAAGAGATGATACATCAGTATAAATTTTTGAAAGACTAT
    TATTTATGTGAATTATTGGCACATTTGATTGAAATACCACAAACATCTTATGACTATATT
    GTGCCAATTCCTTCTTCGCCGGCACATGATTTATCTAGAACATTTAACCCGGTAGAAGCA
    GTACTAAAAGCTAAAGGGATTCGCTTTGATAAGATTTTAAAGATGTCAAATAGACCAAAA
    CAGTCTCATTTAACTAAGAAAGAGCGTCTGGCAGATGAAAATCCATTTATTATTGATACG
    GAATTAGATTTAAATGGTAAGGAAATATTACTCGTTGACGATATTTATACAACTGGATTA
    ACAATTCATCGTGCAGGGTGTAAATTATATGCTAAAAATATCAGAAAATTCAAAGTGTTT
    GCGTTTGCACGATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    675

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS04070 [old locus tag: NWMN_0720 ]
  • symbol: NWMN_RS04070
  • description: competence protein ComF
  • length: 224
  • theoretical pI: 8.7123
  • theoretical MW: 26347.6
  • GRAVY: -0.372768

Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes DNA transformation comF family protein (TIGR00201; HMM-score: 80.7)
    and 3 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis ribose-phosphate diphosphokinase (TIGR01251; EC 2.7.6.1; HMM-score: 24.3)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides hypoxanthine phosphoribosyltransferase (TIGR01203; EC 2.4.2.8; HMM-score: 22.2)
    Metabolism Amino acid biosynthesis Histidine family histidinol-phosphatase (TIGR01261; EC 3.1.3.15; HMM-score: 13.4)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    PRTase-like (CL0533) Pribosyltran; Phosphoribosyl transferase domain (PF00156; HMM-score: 22.4)
    and 3 more
    Zn_Beta_Ribbon (CL0167) DZR; Double zinc ribbon (PF12773; HMM-score: 15.8)
    PRTase-like (CL0533) PRTase_3; PRTase ComF-like (PF15610; HMM-score: 14.5)
    Zn_Beta_Ribbon (CL0167) zinc_ribbon_15; zinc-ribbon family (PF17032; HMM-score: 10.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.027419
    • TAT(Tat/SPI): 0.000516
    • LIPO(Sec/SPII): 0.002876
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKARRCSRCLKHLNQDEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFLKDYYLCELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPKQSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFKVFAFAR

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]