PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus Newman
• locus tag: NWMN_RS05750 [old locus tag: NWMN_1015 ]
• pan locus tag^?: SAUPAN001675000
• symbol: NWMN_RS05750
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Additional information (user-provided)

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: NWMN_RS05750 [old locus tag: NWMN_1015 ]
• symbol: NWMN_RS05750
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 1115916..1117193
• length: 1278
• essential: unknown other strains

⊟Accession numbers

• Location: NC_009641 (1115916..1117193) NCBI
• BioCyc:
• MicrobesOnline: see NWMN_1015

⊟Phenotype

⊟Additional information (user-provided)

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  
  ATGACGAAAGTTAAATTAAACTTTAACAAACCATCTAATGTTTTCAATAGAAACATATTC
  GAAATACTAACCAATTACGATAACTTCACTGAAGTACATTACGGTGGAGGTTCGAGCGGT
  AAGTCTCACGGCGTTATACAAAAAGTTGTACTTAAAGCATTGCAAGACTGGAAATATCCT
  AGGCGTATACTATGGCTTAGAAAAGTCCAATCAACAATTAAAGATAGTTTATTCGAAGAT
  GTCAAAGATTGTTTGATAAACTTCGGTATTTGGGACATGTGCCTTTGGAATAAGACTGAT
  AACAAAGTTGAATTGCCAAACGGCGCAGTTTTTTTGTTTAAAGGATTAGATAACCCAGAG
  AAAATAAAGTCGATAAAAGGCATATCAGACATAGTCATGGAAGAAGCGTCTGAATTCACA
  CTAAATGATTACACGCAATTAACGTTGCGTTTGAGGGAGCGTAAACACGTGAATAAGCAA
  ATATTTTTGATGTTTAACCCAGTATCTAAACTGAATTGGGTTTATAAGTATTTCTTTGAA
  CATGGTGAACCAATGGAAAATGTCATGATTAGACAATCTAGTTATCGAGATAATAAGTTT
  CTTGATGAAATGACACGACAAAACTTAGAGTTGTTAGCAAATCGTAATCCAGCATATTAC
  AAAATTTATGCGTTAGGTGAATTTGCTACACTAGACAAATTGGTTTTCCCTAAGTATGAA
  AAACGTTTAATAAATAAAGATGAGTTAAGACATTTACCTTCTTATTTTGGATTGGACTTT
  GGCTACGTTAATGATCCTAGTGCTTTTATACATTCTAAAATAGATGTAAAGAAAAAGAAG
  TTATACATCATTGAAGAGTATGTTAAACAAGGTATGCTGAATGATGAAATAGCTAATGTC
  ATAAAGCAACTTGGTTATGCTAAAGAAGAAATTACAGCAGATAGTGCAGAACAAAAAAGT
  ATAGCTGAATTAAGGAATCTAGGGCTTAAAAGGATTTTACCAACCAAAAAAGGGAAGGGC
  TCGGTTGTACAAGGGTTACAATTCTTAATGCAATTTGAAATCATTGTTGATGAACGTTGT
  TTCAAGACTATTGAAGAGTTTGACAACTACACATGGCAAAAGGACAAAGATACAGGTGAA
  TATACCAATGAACCAGTAGATACATACAATCATTGTATCGATTCGTTGCGTTATTCAGTG
  GAACGATTCTACAGACCGGTTAGAAAACGCACAAATGTCAGTTCGAAAGTTGACACAATA
  AAATCTCTAGGATTATAG
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1260
  1278
  

⊟Protein

⊟General

• locus tag: NWMN_RS05750 [old locus tag: NWMN_1015 ]
• symbol: NWMN_RS05750
• description: hypothetical protein
• length: 425
• theoretical pI: 9.34345
• theoretical MW: 49912
• GRAVY: -0.512706

⊟Function

• TIGRFAM:
  Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage terminase, large subunit, PBSX family (TIGR01547; HMM-score: 394.5)
• TheSEED: see NWMN_1015
• PFAM:
  P-loop_NTPase (CL0023) Terminase_3; Phage terminase large subunit (PF04466; HMM-score: 205.1)
  and 4 more
  RNase_H (CL0219) Terminase_3C; Terminase RNAseH like domain (PF17288; HMM-score: 136.3)
  P-loop_NTPase (CL0023) Terminase_6N; Terminase large subunit, T4likevirus-type, N-terminal (PF03237; HMM-score: 26.2)
  RNase_H (CL0219) Terminase_6C; Terminase RNaseH-like domain (PF17289; HMM-score: 15.6)
  UBA (CL0214) UBA_3; Fungal ubiquitin-associated domain (PF09288; HMM-score: 12.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.6999
  • Cytoplasmic Membrane Score: 0.0324
  • Cell wall & surface Score: 0.0003
  • Extracellular Score: 0.2674
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.005572
  • TAT(Tat/SPI): 0.000246
  • LIPO(Sec/SPII): 0.000493
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446092091 NCBI
• RefSeq: WP_000169946 NCBI
• UniProt: see NWMN_1015

⊟Additional information (user-provided)

⊟Protein sequence

• MTKVKLNFNKPSNVFNRNIFEILTNYDNFTEVHYGGGSSGKSHGVIQKVVLKALQDWKYPRRILWLRKVQSTIKDSLFEDVKDCLINFGIWDMCLWNKTDNKVELPNGAVFLFKGLDNPEKIKSIKGISDIVMEEASEFTLNDYTQLTLRLRERKHVNKQIFLMFNPVSKLNWVYKYFFEHGEPMENVMIRQSSYRDNKFLDEMTRQNLELLANRNPAYYKIYALGEFATLDKLVFPKYEKRLINKDELRHLPSYFGLDFGYVNDPSAFIHSKIDVKKKKLYIIEEYVKQGMLNDEIANVIKQLGYAKEEITADSAEQKSIAELRNLGLKRILPTKKGKGSVVQGLQFLMQFEIIVDERCFKTIEEFDNYTWQKDKDTGEYTNEPVDTYNHCIDSLRYSVERFYRPVRKRTNVSSKVDTIKSLGL

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Additional information (user-provided)

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Additional information (user-provided)

⊟Other information (user-provided)

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications