From AureoWiki
Jump to navigation Jump to search

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS06610 [old locus tag: NWMN_1172 ]
  • pan locus tag?: SAUPAN003563000
  • symbol: NWMN_RS06610
  • pan gene symbol?: rasP
  • synonym:
  • product: RIP metalloprotease RseP

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS06610 [old locus tag: NWMN_1172 ]
  • symbol: NWMN_RS06610
  • product: RIP metalloprotease RseP
  • replicon: chromosome
  • strand: +
  • coordinates: 1286208..1287494
  • length: 1287
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_009641 (1286208..1287494) NCBI
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    GTGAGCTATTTAGTTACAATAATTGCATTTATTATTGTTTTTGGTGTACTAGTAACTGTT
    CATGAATATGGCCATATGTTTTTTGCGAAAAGAGCAGGCATTATGTGTCCAGAATTTGCG
    ATCGGTATGGGGCCAAAAATTTTTAGTTTTAGAAAAAATGAAACACTTTACACTATTAGG
    TTATTGCCTGTTGGTGGATATGTTCGTATGGCAGGAGATGGCTTAGAAGAGCCACCAGTC
    GAGCCCGGTATGAACGTTAAAATTAAACTTAATGAAGAAAATGAAATAACACATATCATA
    TTAGATGATCATCATAAGTTTCAACAAATTGAAGCGATCGAAGTTAAAAAATGTGATTTT
    AAGGATGACTTATTCATAGAAGGTATCACTGCTTATGATAATGAAAGACATCATTTTAAA
    ATTGCTAGAAAGTCTTTCTTTGTTGAAAATGGTAGCTTAGTTCAAATTGCTCCGAGAGAC
    AGACAATTTGCACATAAAAAGCCATGGCCGAAATTTTTAACATTATTTGCGGGACCGTTA
    TTTAACTTTATATTAGCTTTAGTCCTATTTATTGGTCTTGCATATTATCAAGGCACGCCT
    ACGTCTACTGTAGAACAAGTCGCAGATAAGTATCCAGCTCAACAAGCAGGATTACAAAAA
    GGTGATAAGATCGTCCAAATTGGCAAATATAAAATATCTGAATTTGATGATGTTGATAAG
    GCGTTAGATAAAGTTAAAGATAATAAGACGACTGTTAAATTTGAACGTGATGGTAAAACA
    AAGTCAGTTGAATTAACACCTAAAAAGACTGAAAAAAAACTGACTAAAGTAAGTTCAGAG
    ACGAAGTATGTTCTCGGATTCCAACCAGCGAGTGAACATACACTTTTTAAACCAATTGTA
    TTCGGATTTAAAAGCTTTTTAATCGGTAGTACTTATATTTTTACAGCTGTAGTAGGTATG
    TTGGCTAGTATATTTACGGGCGGATTCTCATTTGATATGTTAAATGGTCCGGTTGGTATT
    TATCATAACGTCGACTCAGTTGTTAAAGCGGGTATCATTAGCTTAATTGGTTACACTGCG
    TTATTAAGTGTAAACTTAGGTATTATGAATTTAATTCCTATTCCTGCACTAGACGGTGGT
    CGTATTTTATTTGTTATATATGAAGCGATTTTCAGAAAACCAGTTAATAAAAAAGCGGAA
    ACAACGATTATTGCTATTGGTGCCATTTTCATGGTCGTTATAATGATATTAGTAACGTGG
    AATGATATTCGACGATATTTCTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1287

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS06610 [old locus tag: NWMN_1172 ]
  • symbol: NWMN_RS06610
  • description: RIP metalloprotease RseP
  • length: 428
  • theoretical pI: 9.54429
  • theoretical MW: 48106.2
  • GRAVY: 0.175234

Function[edit | edit source]

  • reaction:
    EC 3.4.24.-?  ExPASy
  • TIGRFAM:
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides RIP metalloprotease RseP (TIGR00054; EC 3.4.24.-; HMM-score: 287.4)
    and 7 more
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides peptidase Do (TIGR02037; EC 3.4.21.-; HMM-score: 37.8)
    Genetic information processing Protein fate Protein folding and stabilization peptidase Do (TIGR02037; EC 3.4.21.-; HMM-score: 37.8)
    Cellular processes Cellular processes Sporulation and germination stage IV sporulation protein B (TIGR02860; EC 3.4.21.116; HMM-score: 29.5)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides C-terminal processing peptidase (TIGR00225; EC 3.4.21.-; HMM-score: 27)
    Genetic information processing Protein fate Protein modification and repair C-terminal processing peptidase (TIGR00225; EC 3.4.21.-; HMM-score: 27)
    putative carboxyl-terminal-processing protease, deltaproteobacterial (TIGR03900; EC 3.4.21.-; HMM-score: 19.2)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type II secretion system protein C (TIGR01713; HMM-score: 15.9)
  • TheSEED:
  • PFAM:
    Peptidase_MA (CL0126) Peptidase_M50; Peptidase family M50 (PF02163; HMM-score: 254.2)
    and 3 more
    PDZ-like (CL0466) PDZ_2; PDZ domain (PF13180; HMM-score: 44.2)
    PDZ; PDZ domain (Also known as DHR or GLGF) (PF00595; HMM-score: 23.3)
    Tricorn_PDZ; Tricorn protease PDZ domain (PF14685; HMM-score: 13.3)

Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors: Zn2+
  • effectors:
  • protein partners:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.068841
    • TAT(Tat/SPI): 0.002422
    • LIPO(Sec/SPII): 0.004465
  • predicted transmembrane helices (TMHMM): 5

Accession numbers[edit | edit source]

  • GI: 446043261 NCBI
  • RefSeq: WP_000121116 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDRQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDKALDKVKDNKTTVKFERDGKTKSVELTPKKTEKKLTKVSSETKYVLGFQPASEHTLFKPIVFGFKSFLIGSTYIFTAVVGMLASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAETTIIAIGAIFMVVIMILVTWNDIRRYFL

Experimental data[edit | edit source]

  • experimentally validated: no data available

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]