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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS07195 [old locus tag: NWMN_1276 ]
  • pan locus tag?: SAUPAN003757000
  • symbol: NWMN_RS07195
  • pan gene symbol?: umuC
  • synonym:
  • product: DNA repair protein MucB

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS07195 [old locus tag: NWMN_1276 ]
  • symbol: NWMN_RS07195
  • product: DNA repair protein MucB
  • replicon: chromosome
  • strand: +
  • coordinates: 1406214..1407476
  • length: 1263
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (1406214..1407476) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1276

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    GTGTATAATTATCATTTATTAGAAGATAGGGATGTTCTATGTATTGACCAAAAAAGTTTT
    TTTGCGAGTGTTTCTTGTATTGAAAAGGGGCTAGATCCATTAGAAACAAAGCTAGCTGTT
    GTTGCAGATACTAAGCGTCAGGGTTCTGTAATATTGGCTGCGACACCTAAATTAAAAGAA
    TTAGGCATCAAGACAGGGTCGCGATTGTTTGAAATACCACATAGAAATGATATTTACATT
    ATCAATCCAAGTATGCGTAAATATCTTAATGTTTCAGTTGCTATTTCTAAGATTGCATTG
    CGTTATATTCCACCTGAAGATTTACACCAATATAGTATTGACGAATTTTTTATGGATGTT
    ACTGATAGCTATCATAGATTTAGTTCTACAGTACATGCATTTTGCGAAAGACTTAAACGT
    GAAATTTATGAAGAAACAGGCATTTATTGTACTGTGGGCATTGGTTCTAATATGTTATTA
    AGTAAAATTGCTATGGATGTTGAAGCGAAGCATAGTCAAAATGGTATAGCTGAATGGCGA
    TATCAAGATGTACCAACGAAATTATGGCCAATTCAGCCCTTGCGAGATTTTTGGGGTATT
    AATCGTCGAACAGAAGCCAAATTGAATAAAAGAGGAATTTTTACTATAGGAGATTTAGCG
    AAATATCCATATAAATTTTTAAAAAAAGAGTTCGGTATTTTAGGTGTTGATATGCATCTA
    CATGCGAATGGGATAGATCAGAGTAAAGTACGTGAAAAGCACAAGATCAGCAATCCATCG
    ATATGCAAAAGTCAAATATTAATGAGAGATTATCATTTTGATGAAGCAAAAGTAGTAATG
    CAAGAGTTAATTGAAGATGTTGCTAGCAGAGTTCGAGCAAGAAAAAAAGTGGCAAGAACG
    ATACATTTTGCCTTTGGCTATAGTGATGAAGGCGGTGTACATAAGCAATATACTTTGAAA
    GATCCAACAAACTTAGAAAAAGATATTTATAAAGTAGTAATGCATTTCGCAGATAAATTA
    TGTAATAAACAAGCACTATATCGTACGCTAAGTATATCTTTGAGTCAATTTATTAATGAG
    GATGAGCGACAGTTAAGTCTGTTTGAAGATGAATACCAACGCAAACGTGACGAATGTCTA
    GCTAAAACGATAGACCAATTACATTTGAAATACGGCAAAGGTATTGTGTCCAAAGCAGTA
    TCGTTTACAGAAGCAGGTACAAAACACGGCAGATTAGGTTTAATGGCTGGACATAAAATG
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1263

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS07195 [old locus tag: NWMN_1276 ]
  • symbol: NWMN_RS07195
  • description: DNA repair protein MucB
  • length: 420
  • theoretical pI: 9.23261
  • theoretical MW: 48426.6
  • GRAVY: -0.393571

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined IMS; impB/mucB/samB family (PF00817; HMM-score: 117.2)
    and 2 more
    IMS_C; impB/mucB/samB family C-terminal domain (PF11799; HMM-score: 56.2)
    HHH (CL0198) IMS_HHH; IMS family HHH motif (PF11798; HMM-score: 37.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004875
    • TAT(Tat/SPI): 0.002363
    • LIPO(Sec/SPII): 0.013254
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MYNYHLLEDRDVLCIDQKSFFASVSCIEKGLDPLETKLAVVADTKRQGSVILAATPKLKELGIKTGSRLFEIPHRNDIYIINPSMRKYLNVSVAISKIALRYIPPEDLHQYSIDEFFMDVTDSYHRFSSTVHAFCERLKREIYEETGIYCTVGIGSNMLLSKIAMDVEAKHSQNGIAEWRYQDVPTKLWPIQPLRDFWGINRRTEAKLNKRGIFTIGDLAKYPYKFLKKEFGILGVDMHLHANGIDQSKVREKHKISNPSICKSQILMRDYHFDEAKVVMQELIEDVASRVRARKKVARTIHFAFGYSDEGGVHKQYTLKDPTNLEKDIYKVVMHFADKLCNKQALYRTLSISLSQFINEDERQLSLFEDEYQRKRDECLAKTIDQLHLKYGKGIVSKAVSFTEAGTKHGRLGLMAGHKM

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]