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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS08015 [old locus tag: NWMN_1419 ]
  • pan locus tag?: SAUPAN004067000
  • symbol: NWMN_RS08015
  • pan gene symbol?:
  • synonym:
  • product: membrane protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS08015 [old locus tag: NWMN_1419 ]
  • symbol: NWMN_RS08015
  • product: membrane protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1589654..1590634
  • length: 981
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (1589654..1590634) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1419

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGTTAAAGTTAAATCCTTACAAGATTGGATTTAGAACAATAAAAACAGCAGTGGGTATG
    ACTTTAGGTGTAATTATTAGTAAGCTGTTAGGTTTAGATAATTATGCTTCAAGCGCCATA
    TTAGTCGTATTATGTATTAAACATACAAAAGTACATTCGCTACAAGCGATTATTTCAAGA
    TTAGTATCATGTTTTTTAGTATTGTTTTTAGGTTCAGCAATATTTAGTTTATTAGGTCAG
    AGTCCAATTGTACTCGGTATTATCGTATTGTTATTTATACCATTAACTGTCGTATTAAAA
    GTACAAGAAGGTGTCATTACGAGTTGCGTTATATTACTTCATGTTTTTAATGCAAAATCA
    ATTGATGCACATTTAATTGTTAATGAAACATTATTACTGTTAATTGGACTAAGCATTGCA
    TTTACAATGAATTTAATGATGCCAAGTTTAGACAAACAACTAGACGAATACAAATGTAAA
    ATTGAGCAACAAATTGCTGATATTTTTAGTAAATATAGTTATATTTGTGAAAAATATGAA
    GATACCATTGCGATTGAATTTGAAGTGTTACTTTTAAATATTAAAAAGGCGAAGTCTATC
    GCGTTCCGAGATGTTAAAAATCATTTTGTTAGAAACGAAAATTCATACTATCATTATTTT
    GATATGCGAGAAGAGCAAGTGGAATTGTTAATGAGAATGAAACCGCTCATCGAAAGTATC
    TGTCATAAAGATCCGCTTTTAAATGATGTTGCGTCACTGCTGAAAGAAATTGGTCTAAAT
    GTGAATAGTAATGACTATACAGCAATGCGTTTACACAATTTGTATGAGACGCGTTTGAAA
    TTGGATGAACTGCCATTGCCAACAACACACAAAGCGCTTAACTCGAGAGCAAGTATTATT
    CAAATATTAAATGAATTAGAAGAATATTTACAAATCAAATCGCAATTTGGTTCATTGAAA
    ATGCATAGTGAAGTAGCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    981

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS08015 [old locus tag: NWMN_1419 ]
  • symbol: NWMN_RS08015
  • description: membrane protein
  • length: 326
  • theoretical pI: 7.87526
  • theoretical MW: 36972.7
  • GRAVY: 0.371166

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    FUSC (CL0307) ArAE_1; Aromatic acid exporter family member 1 (PF06081; HMM-score: 146)
    no clan defined ArAE_1_C; Putative aromatic acid exporter C-terminal domain (PF11728; HMM-score: 144.1)
    and 3 more
    FUSC (CL0307) FUSC_2; Fusaric acid resistance protein-like (PF13515; HMM-score: 18.2)
    DUF2955; Protein of unknown function (DUF2955) (PF11168; HMM-score: 17.6)
    Ig (CL0011) K1; K1 glycoprotein (PF02960; HMM-score: 14.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.030722
    • TAT(Tat/SPI): 0.000799
    • LIPO(Sec/SPII): 0.006908
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MLKLNPYKIGFRTIKTAVGMTLGVIISKLLGLDNYASSAILVVLCIKHTKVHSLQAIISRLVSCFLVLFLGSAIFSLLGQSPIVLGIIVLLFIPLTVVLKVQEGVITSCVILLHVFNAKSIDAHLIVNETLLLLIGLSIAFTMNLMMPSLDKQLDEYKCKIEQQIADIFSKYSYICEKYEDTIAIEFEVLLLNIKKAKSIAFRDVKNHFVRNENSYYHYFDMREEQVELLMRMKPLIESICHKDPLLNDVASLLKEIGLNVNSNDYTAMRLHNLYETRLKLDELPLPTTHKALNSRASIIQILNELEEYLQIKSQFGSLKMHSEVA

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]