Jump to navigation
Jump to search
NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_RS08755 [old locus tag: NWMN_1561 ]
- pan locus tag?: SAUPAN004282000
- symbol: NWMN_RS08755
- pan gene symbol?: hemL
- synonym:
- product: glutamate-1-semialdehyde 2,1-aminomutase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_RS08755 [old locus tag: NWMN_1561 ]
- symbol: NWMN_RS08755
- product: glutamate-1-semialdehyde 2,1-aminomutase
- replicon: chromosome
- strand: -
- coordinates: 1727560..1728846
- length: 1287
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261ATGAGATATACGAAATCAGAAGAAGCAATGAAGGTTGCTGAAACTTTAATGCCTGGTGGT
GTAAATAGTCCAGTACGCGCATTTAAATCAGTAGATACACCAGCAATTTTTATGGATCAC
GGTAAAGGTTCAAAAATTTATGATATCGATGGTAACGAGTATATCGACTATGTACTAAGT
TGGGGACCACTTATTTTAGGACATAGAGACCCTCAAGTTATTAGTCATTTACATGAAGCA
ATTGATAAAGGTACAAGTTTTGGTGCATCAACATTACTTGAAAATAAATTGGCGCAGCTC
GTTATTGACCGAGTACCTTCAATAGAAAAAGTGCGTATGGTGTCATCTGGTACAGAAGCT
ACATTGGATACTTTAAGATTAGCACGTGGTTATACTGGCAGAAATAAAATTGTGAAATTT
GAAGGTTGCTATCATGGTCATAGTGATTCGTTATTAATCAAAGCTGGTTCTGGGGTGGCA
ACATTAGGATTGCCGGATTCTCCTGGTGTGCCTGAAGGTATTGCTAAAAATACAATTACA
GTTCCATACAATGATTTAGATGCACTTAAAATCGCTTTCGAAAAATTTGGAAACGATATT
GCTGGTGTAATCGTAGAACCTGTTGCTGGTAATATGGGTGTCGTACCGCCGATTGAAGGT
TTTTTACAGGGATTAAGAGATATTACGACTGAATACGGCGCATTGCTAATTTTCGATGAA
GTAATGACTGGTTTCAGAGTCGGTTATCATTGTGCACAAGGTTACTTTGGTGTGACACCA
GATTTAACTTGCTTAGGAAAAGTTATCGGTGGAGGACTACCTGTAGGTGCATTTGGTGGT
AAAAAAGAAATCATGGATCATATAGCACCATTAGGAAATATTTATCAAGCGGGTACGTTA
TCAGGAAATCCTCTTGCAATGACAAGTGGTTATGAAACGTTAAGCCAATTAACGCCAGAG
ACATATGAGTATTTTAATATGTTAGGCGATATACTTGAAGACGGTTTAAAACGTGTATTT
GCTAAACACAATGTACCAATAACTGTAAATAGAGCAGGTTCAATGATTGGTTATTTCTTA
AATGAAGGACCTGTAACTAATTTTGAACAAGCGAATAAAAGTGATTTGAAATTATTTGCA
GAAATGTATCGAGAAATGGCAAAAGAAGGTGTGTTTTTACCACCATCTCAATTTGAAGGT
ACATTCTTATCTACGGCACACACGAAAGAAGATATTGAAAAAACGATTCAAGCATTTGAT
ACGGCTTTAAGTCGTATTGTAAAATAA60
120
180
240
300
360
420
480
540
600
660
720
780
840
900
960
1020
1080
1140
1200
1260
1287
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_RS08755 [old locus tag: NWMN_1561 ]
- symbol: NWMN_RS08755
- description: glutamate-1-semialdehyde 2,1-aminomutase
- length: 428
- theoretical pI: 5.29503
- theoretical MW: 46387.8
- GRAVY: -0.0616822
⊟Function[edit | edit source]
- reaction: EC 5.4.3.8? ExPASyGlutamate-1-semialdehyde 2,1-aminomutase (S)-4-amino-5-oxopentanoate = 5-aminolevulinate
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin glutamate-1-semialdehyde-2,1-aminomutase (TIGR00713; EC 5.4.3.8; HMM-score: 624.6)and 10 moretransaminase, acetylornithine/succinylornithine family (TIGR00707; HMM-score: 179)Energy metabolism Amino acids and amines succinylornithine transaminase family (TIGR03246; EC 2.6.1.81; HMM-score: 143.1)ornithine--oxo-acid transaminase (TIGR01885; EC 2.6.1.13; HMM-score: 134.9)Central intermediary metabolism Other 4-aminobutyrate transaminase (TIGR00700; EC 2.6.1.19; HMM-score: 132.6)Central intermediary metabolism Other 2,4-diaminobutyrate 4-transaminase (TIGR00709; EC 2.6.1.-; HMM-score: 125.3)Central intermediary metabolism Polyamine biosynthesis putrescine aminotransferase (TIGR03372; EC 2.6.1.82; HMM-score: 121.1)Biosynthesis of cofactors, prosthetic groups, and carriers Biotin adenosylmethionine-8-amino-7-oxononanoate transaminase (TIGR00508; EC 2.6.1.62; HMM-score: 120.8)Cellular processes Adaptations to atypical conditions diaminobutyrate--2-oxoglutarate aminotransferase (TIGR02407; EC 2.6.1.76; HMM-score: 89.9)L-lysine 6-transaminase (TIGR03251; EC 2.6.1.36; HMM-score: 46.7)Central intermediary metabolism Other 4-aminobutyrate aminotransferase (TIGR00699; EC 2.6.1.19; HMM-score: 29.1)
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: PLP_aminotran (CL0061) Aminotran_3; Aminotransferase class-III (PF00202; HMM-score: 246.9)and 1 moreAminotran_1_2; Aminotransferase class I and II (PF00155; HMM-score: 16.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors: pyridoxal 5'-phosphate
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.024734
- TAT(Tat/SPI): 0.002182
- LIPO(Sec/SPII): 0.001986
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MRYTKSEEAMKVAETLMPGGVNSPVRAFKSVDTPAIFMDHGKGSKIYDIDGNEYIDYVLSWGPLILGHRDPQVISHLHEAIDKGTSFGASTLLENKLAQLVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIVKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLDALKIAFEKFGNDIAGVIVEPVAGNMGVVPPIEGFLQGLRDITTEYGALLIFDEVMTGFRVGYHCAQGYFGVTPDLTCLGKVIGGGLPVGAFGGKKEIMDHIAPLGNIYQAGTLSGNPLAMTSGYETLSQLTPETYEYFNMLGDILEDGLKRVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEQANKSDLKLFAEMYREMAKEGVFLPPSQFEGTFLSTAHTKEDIEKTIQAFDTALSRIVK
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.