COLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus Newman
• locus tag: NWMN_RS10405
• pan locus tag^?:
• symbol: NWMN_RS10405
• pan gene symbol^?: —
• synonym:
• product: transcriptional regulator

⊟Gene

⊟General

• type: CDS
• locus tag: NWMN_RS10405
• symbol: NWMN_RS10405
• product: transcriptional regulator
• replicon: chromosome
• strand: -
• coordinates: 2019808..2020041
• length: 234
• essential: unknown

⊟Accession numbers

• Location: NC_009641 (2019808..2020041) NCBI
• BioCyc:
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  
  TTGAAATTAGATGAATGGCGAAAACGAAAAGGTTACACCCAGTCATCTTTCGCAGAAAAA
  CTTGGCATTTCACCGTCTACTTATAACATTTGGGAAAACAACCCAGAAATGATTAAACCT
  AGAGATGCTTTTAGAATTGCTAAGACATTAGATATCTCTATTGATGAGATTATTTTTTTA
  AAAGATGAATCGTATTTTAAATACGTTTTAGTCGAAGAAAAACAAACATCTTAA
  60
  120
  180
  234
  

⊟Protein

⊟General

• locus tag: NWMN_RS10405
• symbol: NWMN_RS10405
• description: transcriptional regulator
• length: 77
• theoretical pI: 6.84599
• theoretical MW: 9181.42
• GRAVY: -0.692208

⊟Function

• TIGRFAM:
  Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 15.4)
  putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 13.9)
• TheSEED:
• PFAM:
  HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 53.3)
  and 9 more
  HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 38.7)
  HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 30)
  HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 29.5)
  HTH_23; Homeodomain-like domain (PF13384; HMM-score: 19.6)
  HTH_Tnp_1_2; Helix-turn-helix of insertion element transposase (PF13022; HMM-score: 13.9)
  HTH_10; HTH DNA binding domain (PF04967; HMM-score: 13.3)
  YdaS_antitoxin; Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT (PF15943; HMM-score: 12.5)
  HTH_28; Helix-turn-helix domain (PF13518; HMM-score: 12.2)
  HTH_8; Bacterial regulatory protein, Fis family (PF02954; HMM-score: 11.6)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.005723
  • TAT(Tat/SPI): 0.000254
  • LIPO(Sec/SPII): 0.001157
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446685107 NCBI
• RefSeq: WP_000762453 NCBI
• UniProt:

⊟Protein sequence

• MKLDEWRKRKGYTQSSFAEKLGISPSTYNIWENNPEMIKPRDAFRIAKTLDISIDEIIFLKDESYFKYVLVEEKQTS

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Other Information

You are kindly invited to share additional interesting facts.