From AureoWiki
Jump to navigation Jump to search

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS12565 [old locus tag: NWMN_2174 ]
  • pan locus tag?: SAUPAN005735000
  • symbol: NWMN_RS12565
  • pan gene symbol?: moaC
  • synonym:
  • product: cyclic pyranopterin monophosphate synthase MoaC

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS12565 [old locus tag: NWMN_2174 ]
  • symbol: NWMN_RS12565
  • product: cyclic pyranopterin monophosphate synthase MoaC
  • replicon: chromosome
  • strand: +
  • coordinates: 2397923..2398417
  • length: 495
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (2397923..2398417) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_2174

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGACTGAGTTTACTCATATTAATCAACAAGGCCACGCCAAAATGGTCGATGTATCAGAC
    AAACAAATTACAAAAAGAACTGCTGTCGCTCATTCAAGCATTACTGTAAATGAAACTATT
    TTTAAGCAGATTTCTAATAACACCAATACCAAAGGCAATGTATTGAACACTGCTCAAATC
    GCTGGTATTATGGCTGCCAAAAATACATCAACACTTATTCCGATGTGCCATCCATTACCA
    TTGACTGGCATAGATGTTCACTTCAGCTGGGATGAAACAAATGCACCCCTTTATACTTTA
    AACATTCAAACAACTGTCTCTACAACTGGCAAAACCGGTGTTGAAATGGAAGCTTTAACC
    GCTGCATCAGCAACGGCTTTAACCATTTACGACATGACGAAAGCAGTTGATAAAGGTATG
    ATTATTGGCGAAACCTACCTTGAAAGCAAGTCTGGCGGTAAATCTGGAGATTTTCAACGC
    CAATCAAATCAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    495

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS12565 [old locus tag: NWMN_2174 ]
  • symbol: NWMN_RS12565
  • description: cyclic pyranopterin monophosphate synthase MoaC
  • length: 164
  • theoretical pI: 7.07168
  • theoretical MW: 17693.9
  • GRAVY: -0.281707

Function[edit | edit source]

  • reaction:
    EC 4.6.1.17?  ExPASy
    Cyclic pyranopterin monophosphate synthase (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate
  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Molybdopterin molybdenum cofactor biosynthesis protein C (TIGR00581; HMM-score: 200.8)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined MoaC; MoaC family (PF01967; HMM-score: 179.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.012774
    • TAT(Tat/SPI): 0.001948
    • LIPO(Sec/SPII): 0.001684
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]