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NCBI: 26-AUG-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0912 [new locus tag: SA_RS05170 ]
  • pan locus tag?: SAUPAN003269000
  • symbol: qoxB
  • pan gene symbol?: qoxB
  • synonym:
  • product: quinol oxidase polypeptide I QoxB

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA0912 [new locus tag: SA_RS05170 ]
  • symbol: qoxB
  • product: quinol oxidase polypeptide I QoxB
  • replicon: chromosome
  • strand: -
  • coordinates: 1035703..1037691
  • length: 1989
  • essential: yes DEG other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    ATGAATTTTCCATGGGATCAATTACTAGTTAAAGGTAACTGGATGATTACAATGGCACAA
    ATTGGTGCCCCATTCTTAGTTATTGGTTTAATCGCAGTAATTACTTACTTTAAATTATGG
    AAATATCTTTACAAAGAATGGTTCACATCTGTAGACCATAAGAAAATCGGTATTATGTAT
    TTAATCTGTGCCGTATTAATGTTCGTCCGTGGTGGTATTGATGCGTTACTTATTCGTGCG
    CAATTAACAGTACCTGATAACAAATTTTTAGAATCTAACCACTATAACGAAATTTTTAGT
    ACACATGGTGTAATCATGATTATCTTCATGGCAATGCCATTTATCTTTGGTTTATGGAAT
    ATCGTTGTTCCATTACAAATTGGAGCACGTGATGTTGCATTCCCAGTATTAAACAACGTA
    AGTTTCTGGCTATTCTTTGCAGGTATGATTTTATTCAACCTGTCATTTATTATTGGTGGT
    TCACCAGCAGCTGGTTGGACAAACTATGCGCCACTAGCAGGTGAATTCAGTCCTGGTCCG
    GGTGTTAACTATTACTTAATAGCTATACAAATTTCAGGGCTTGGTACCTTAGCTACAGGT
    ATCAACTTCTTTGTAACAATTTTAAGATGTAAAACACCAACTATGAAGTTTATGCAAATG
    CCAATGTTTACAGTAACAACATTTATTACTACATTAATTGTTATTCTTGCTTTCCCTCCT
    TTAACAGTAGCGTTAGCATTAATGACAACTGATAGAATATTTGACACAGCATTCTTCACA
    GTTGCACATGGCGGTATGCCAATGCTTTGGGCTAACTTCTTCTGGGTATGGGGGCACCCT
    GAAGTTTATATCGTTATCCTTCCAGCATTTGGTATTTACTCAGAAATTATCCCGACATTC
    GCTCGTAAGCGTTTATTCGGACATCAAAGTATGGTATGGGCAACTGCCGGTATCGCGTTC
    CTTAGTTTCTTAGTTTGGGTTCACCATTTCTTCACAATGGGTAATGGTGCGTTAATCAAC
    TCATTCTTCTCAATTTCAACAATGCTGATTGGTATTCCAACTGGTGTGAAATTGTTTAAC
    TGGTTATTAACATTATATAAAGGACGTATTACATTTGAGTCACCAATGCTATTCTCATTA
    GCATTTATCCCTAACTTCCTTTTAGGTGGTGTTACGGGTGTAATGTTAGCAATGGCATCA
    GCTGACTATCAATATCACAATACGTACTTCTTAGTAGCTCACTTCCACTATACATTGGTT
    ACTGGTGTTGTATTTGCCTGCTTAGCTGGTTTAATCTTCTGGTATCCAAAGATGATGGGT
    TACAAATTAAACGAAACATTAAACAAATGGTGCTTCTGGTTCTTCATGATCGGATTTAAC
    GTTTGTTTCTTACCACAATTCATTCTTGGATTAGATGGTATGCCACGTCGTTTATACACT
    TATATGCCATCAGATGGTTGGTTCTTATTAAACTTAATTTCAACTATCGGTGCATTATTA
    ATGGCAATCGGATTCTTATTCCTTGTTGTTAGTATCGTATACAGTCACTTCAAATCTCCA
    CGTGAAGCAACTGGAGATAACTGGGATGGCCTTGGCCGTACTCTAGAGTGGACTACTGCA
    TCAGCAATTCCACCTAAATACAACTTTGCCATTACACCAGATTGGAATGACTACGACACA
    TTTGTTGATATGAAAGAACATGGTCGTCATTACTTAGACAACCATAATTACAAAGACATT
    CATATGCCAAACAATACTCCTGTTGGATTCTGGATTGGTATCTTTATGACTATCGGCGGT
    TTCTTCTTAATTTTCGAAACTGTAATTCCAGCATTAATTTGTTTATTCGGTATTTTTGGT
    ACTATGATTTATCGCAGTTTCCAAATCGATCACGGATATCATATCCCTGCTGCTGAAGTT
    GCTGAAACTGAAGCTAGATTAAGAGAAGCGCGTATTAAAGAAAGGGAGGCTGTAAGTCAT
    GAGTCATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    1989

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA0912 [new locus tag: SA_RS05170 ]
  • symbol: QoxB
  • description: quinol oxidase polypeptide I QoxB
  • length: 662
  • theoretical pI: 7.7182
  • theoretical MW: 75242.4
  • GRAVY: 0.585499

⊟Function[edit | edit source]

  • reaction:
    EC 1.10.3.-?  ExPASy
    2 a quinol + O2 = 2 a quinone + 2 H2O?
  • TIGRFAM:
    Metabolism Energy metabolism Electron transport cytochrome aa3 quinol oxidase, subunit I (TIGR02882; EC 1.10.3.-; HMM-score: 1267.6)
    and 3 more
    Metabolism Energy metabolism Electron transport cytochrome o ubiquinol oxidase, subunit I (TIGR02843; EC 1.10.3.-; HMM-score: 795.8)
    Metabolism Energy metabolism Electron transport cytochrome c oxidase, subunit I (TIGR02891; EC 1.9.3.1; HMM-score: 624.9)
    glycosyltransferase, TIGR04182 family (TIGR04182; HMM-score: 10)
  • TheSEED  :
    • AA3-600 quinol oxidase subunit I
    Respiration Electron accepting reactions Terminal cytochrome C oxidases  quinol oxidase polypeptide I QoxB (EC:1.9.3.-)
  • PFAM:
    no clan defined COX1; Cytochrome C and Quinol oxidase polypeptide I (PF00115; HMM-score: 464)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors: Cu cation, ferriheme a
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 14
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.000531
    • TAT(Tat/SPI): 0.000191
    • LIPO(Sec/SPII): 0.022872
  • predicted transmembrane helices (TMHMM): 15

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNFPWDQLLVKGNWMITMAQIGAPFLVIGLIAVITYFKLWKYLYKEWFTSVDHKKIGIMYLICAVLMFVRGGIDALLIRAQLTVPDNKFLESNHYNEIFSTHGVIMIIFMAMPFIFGLWNIVVPLQIGARDVAFPVLNNVSFWLFFAGMILFNLSFIIGGSPAAGWTNYAPLAGEFSPGPGVNYYLIAIQISGLGTLATGINFFVTILRCKTPTMKFMQMPMFTVTTFITTLIVILAFPPLTVALALMTTDRIFDTAFFTVAHGGMPMLWANFFWVWGHPEVYIVILPAFGIYSEIIPTFARKRLFGHQSMVWATAGIAFLSFLVWVHHFFTMGNGALINSFFSISTMLIGIPTGVKLFNWLLTLYKGRITFESPMLFSLAFIPNFLLGGVTGVMLAMASADYQYHNTYFLVAHFHYTLVTGVVFACLAGLIFWYPKMMGYKLNETLNKWCFWFFMIGFNVCFLPQFILGLDGMPRRLYTYMPSDGWFLLNLISTIGALLMAIGFLFLVVSIVYSHFKSPREATGDNWDGLGRTLEWTTASAIPPKYNFAITPDWNDYDTFVDMKEHGRHYLDNHNYKDIHMPNNTPVGFWIGIFMTIGGFFLIFETVIPALICLFGIFGTMIYRSFQIDHGYHIPAAEVAETEARLREARIKEREAVSHES

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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