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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0964 [new locus tag: SA_RS05460 ]
  • pan locus tag?: SAUPAN003342000
  • symbol: SA0964
  • pan gene symbol?: ctaA
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA0964 [new locus tag: SA_RS05460 ]
  • symbol: SA0964
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1094834..1095745
  • length: 912
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    TTGTTTGGCAAAAAGAATTTAAAATGGTTAGGTGTCGTAGCAACGTTAATGATGACATTT
    GTACAACTTGGTGGAGCCTTAGTTACCAAAACCGGATCAGCTGATGGTTGTGGTTCTTCT
    TGGCCACTATGTCATGGTGCGTTGATTCCAGAATTCTTTCCTATTGATACGATTATTGAG
    TTAAGTCATAGAGCCGTTTCAGCTTTGTCTTTATTAATGGTCTTATGGTTAGTTATCACT
    GCATGGAAACATATAGGCTATATTAAAGAAATTAAACCTTTATCAATCATTAGTGTTGGA
    TTCTTATTATTGCAAGCATTAATCGGAGCTGCCGCTGTTATTTGGCAACAAAACGATTAC
    GTTTTAGCATTGCACTTTGGTATATCATTAATCAGTTTCTCATCTGTATTTTTAATAACA
    TTGATTATTTTCTCTATAGATCAAAAATATGAAGCTGACGAATTATATATCAAAAAGCCA
    TTAAGACGTTTAACATGGTTAATGGCAATCATCATTTATTGTGGTGTTTATACTGGTGCA
    CTAGTGAGACATGCGGATGCAAGTTTAGCATATGGTGGTTGGCCATTGCCATTCCACGAT
    CTTGTACCACATTCAGAACAAGATTGGGTTCAACTCACGCATCGTATCATGGCTTTTATA
    GTGTTTACGATTATTATGATTACTTATATTCACGCTGTTAAAAATTATCCAAATAATCGT
    ACTGTTCATTATGGTTATACAGCTGCATTTATACTTGTTATATTACAAGTTATCACAGGT
    GCATTATCTATTATGACAAATGTTAACCTGATAATCGCACTTTTCCATGCATTATTTATC
    ACTTATTTATTTGGTATGACAACATACTTTATCATGCTAATGTTACGATCAGTAAGAAGT
    GACAAGCAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    912

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA0964 [new locus tag: SA_RS05460 ]
  • symbol: SA0964
  • description: hypothetical protein
  • length: 303
  • theoretical pI: 9.19403
  • theoretical MW: 34059.4
  • GRAVY: 0.762046

Function[edit | edit source]

  • reaction:
    EC 1.3.-.-?  ExPASy
  • TIGRFAM:
    methanobactin biosynthesis cassette protein MbnC (TIGR04160; HMM-score: 13)
    surface glycoprotein signal peptide (TIGR04207; HMM-score: 11.8)
  • TheSEED  :
    • Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA
    Respiration Respiration - no subcategory Biogenesis of cytochrome c oxidases  Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA
  • PFAM:
    2heme_cytochrom (CL0328) COX15-CtaA; Cytochrome oxidase assembly protein (PF02628; HMM-score: 116.2)
    and 3 more
    no clan defined DUF4231; Protein of unknown function (DUF4231) (PF14015; HMM-score: 9.9)
    GT-C (CL0111) YfhO; Bacterial membrane protein YfhO (PF09586; HMM-score: 8.3)
    GPCR_A (CL0192) 7TMR-DISM_7TM; 7TM diverse intracellular signalling (PF07695; HMM-score: 7.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: Signal peptide SP(Sec/SPI) length 34 aa
    • SP(Sec/SPI): 0.833133
    • TAT(Tat/SPI): 0.017571
    • LIPO(Sec/SPII): 0.045928
    • Cleavage Site: CS pos: 34-35. GSA-DG. Pr: 0.3680
  • predicted transmembrane helices (TMHMM): 8

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MFGKKNLKWLGVVATLMMTFVQLGGALVTKTGSADGCGSSWPLCHGALIPEFFPIDTIIELSHRAVSALSLLMVLWLVITAWKHIGYIKEIKPLSIISVGFLLLQALIGAAAVIWQQNDYVLALHFGISLISFSSVFLITLIIFSIDQKYEADELYIKKPLRRLTWLMAIIIYCGVYTGALVRHADASLAYGGWPLPFHDLVPHSEQDWVQLTHRIMAFIVFTIIMITYIHAVKNYPNNRTVHYGYTAAFILVILQVITGALSIMTNVNLIIALFHALFITYLFGMTTYFIMLMLRSVRSDKQ

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]