PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA1816 [new locus tag: SA_RS10430 ]
• pan locus tag^?: SAUPAN005242000
• symbol: sel
• pan gene symbol^?: sel
• synonym:
• product: extracellular enterotoxin L

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA1816 [new locus tag: SA_RS10430 ]
• symbol: sel
• product: extracellular enterotoxin L
• replicon: chromosome
• strand: +
• coordinates: 2057159..2057881
• length: 723
• essential: no DEG

⊟Accession numbers

• Gene ID: 1124708 NCBI
• RefSeq: NP_375117 NCBI
• BioCyc: see SA_RS10430
• MicrobesOnline: 104143 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  ATGAAAAAAAGATTATTATTTGTAATTGTTATTACTTTATTTATTTTTTCTTCTAATCAT
  ACAGTCTTATCTAACGGCGATGTAGGTCCAGGAAATCTAAGAAATTTTTATACTAAATAT
  GAATATGTGAATTTAAAGAATGTTAAAGACAAAAATTCACCAGAATCACACCGCTTAGAA
  TACTCGTATAAAAATGATACATTGTATGCTGAATTTGACAATGAATATATAACTAGTGAT
  CTAAAGGGAAAAAATGTCGATGTTTTTGGTATAAGCTATAAATATGGTTCTAACTCTCGT
  ACTATATATGGTGGTGTTACTAAAGCAGAAAACAATAAATTAGATTCGCCAAGAATAATA
  CCTATAAATTTAATTATCAATGGCAAGCATCAAACAGTTACAACTAAAAGTGTTTCTACA
  GATAAAAAAATGGTTACCGCACAAGAAATAGATGTCAAACTAAGAAAATACTTGCAAGAT
  GAATTTAATATTTATGGACACAATGATACTGGTAAAGGTAAAGAATACGGCACTTCTTCA
  AAATTTTATAGCGGTTTTGATAAGGGGAGTGTAGTATTCCATATGAATGATGGTTCTAAT
  TTCTCGTATGATTTATTTTACACAGGATACGGTCTTCCAGAAAGCTTCTTAAAAATTTAC
  AAAGATAATAAAACTGTTGATTCAACACAATTTCATCTAGATGTCGAAATTTCAAAAAGA
  TGA
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  723
  

⊟Protein

⊟General

• locus tag: SA1816 [new locus tag: SA_RS10430 ]
• symbol: Sel
• description: extracellular enterotoxin L
• length: 240
• theoretical pI: 9.41784
• theoretical MW: 27495.7
• GRAVY: -0.618333

⊟Function

• TIGRFAM:
• TheSEED  :
  • Phage exotoxin
  • Superantigen enterotoxin SEL
  Phages, Prophages, Transposable elements, Plasmids Pathogenicity islands Staphylococcal pathogenicity islands SaPI  Superantigen enterotoxin SEL
• PFAM:
  Ant-toxin_C (CL0386) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 124.2)
  and 1 more
  OB_enterotoxin (CL0658) Stap_Strp_toxin; Staphylococcal/Streptococcal toxin, OB-fold domain (PF01123; HMM-score: 27.6)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Extracellular
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0
  • Cellwall Score: 0
  • Extracellular Score: 10
  • Internal Helix: 1
• LocateP: N-terminally anchored (No CS)
  • Prediction by SwissProt Classification: Membrane
  • Pathway Prediction: Sec-(SPI)
  • Intracellular possibility: 0.17
  • Signal peptide possibility: 1
  • N-terminally Anchored Score: 2
  • Predicted Cleavage Site: No CleavageSite
• SignalP: Signal peptide SP(Sec/SPI) length 24 aa
  • SP(Sec/SPI): 0.960599
  • TAT(Tat/SPI): 0.000634
  • LIPO(Sec/SPII): 0.032425
  • Cleavage Site: CS pos: 24-25. VLS-NG. Pr: 0.6790
• predicted transmembrane helices (TMHMM): 1

⊟Accession numbers

• GI: 15927584 NCBI
• RefSeq: NP_375117 NCBI
• UniProt: A0A0H3JNB4 UniProt

⊟Protein sequence

• MKKRLLFVIVITLFIFSSNHTVLSNGDVGPGNLRNFYTKYEYVNLKNVKDKNSPESHRLEYSYKNDTLYAEFDNEYITSDLKGKNVDVFGISYKYGSNSRTIYGGVTKAENNKLDSPRIIPINLIINGKHQTVTTKSVSTDKKMVTAQEIDVKLRKYLQDEFNIYGHNDTGKGKEYGTSSKFYSGFDKGSVVFHMNDGSNFSYDLFYTGYGLPESFLKIYKDNKTVDSTQFHLDVEISKR

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: no polycistronic organisation predicted

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications