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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0869 [new locus tag: SACOL_RS04460 ]
  • pan locus tag?: SAUPAN002811000
  • symbol: SACOL0869
  • pan gene symbol?: —
  • synonym:
  • product: phosphoglycerate mutase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL0869 [new locus tag: SACOL_RS04460 ]
  • symbol: SACOL0869
  • product: phosphoglycerate mutase
  • replicon: chromosome
  • strand: +
  • coordinates: 892328..892918
  • length: 591
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    GTGTTATTGTTGGCTAAAACGTTATATTTAATGCGCCACGGACAAACTTTGTTTAATTTT
    AAGGGACTAATTCAGGGATTTGGAGATTCGCCGCTAACAGAACTTGGAATTGCTCAAGCT
    CAAAAGGCACGTAGTTATTATGAAACTAAGGGGATAAACTTCGATTTATATGCATCATCA
    ACGCAAGAACGCGCAAGTGACACACTTGAAAATGTTGCACCTAACCAATCGTATCAACGT
    TTTAAGGGACTGAAGGAATGGCATTTTGGAATATTTGAAGGTGAGTCAGTCTATCTATTT
    GATAATCTATACAAGCCTGAGGACTTATTCGGAGATCGAATTGTTCCTTTCAAAGGAGAG
    GCAAGGCAACAAGTTGAAGAACGCATTGTGAAAACTTTACATGACATTATGTCTCAAACA
    AAGAATAATGCATTAGTCGTGAGTCATGGAACAATAATGGGAGTATTTTTAAGATATTGC
    CTTAAACTAGATGAAGCATTAAAGCATAATATCGGTAATTGTAATATCCTGAAATTTGAA
    TATGACAATGGAACATTTAAATTTGTTGAGTTAATTGATCCAAATTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    591

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL0869 [new locus tag: SACOL_RS04460 ]
  • symbol: SACOL0869
  • description: phosphoglycerate mutase
  • length: 196
  • theoretical pI: 6.67902
  • theoretical MW: 22502.5
  • GRAVY: -0.306633

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin alpha-ribazole phosphatase (TIGR03162; EC 3.1.3.73; HMM-score: 71.1)
    and 3 more
    phosphoglycerate mutase 1 family (TIGR01258; HMM-score: 41.3)
    probable phosphomutase, MSMEG_4193 family (TIGR03848; EC 5.4.2.-; HMM-score: 27.8)
    Signal transduction Regulatory functions Protein interactions phosphohistidine phosphatase SixA (TIGR00249; EC 3.1.3.-; HMM-score: 26.1)
  • TheSEED  :
    • phosphoglycerate mutase family protein
    Experimental tye  Hypothetical, related to broad specificity phosphatases COG0406
  • PFAM:
    His_phosphatase (CL0071) His_Phos_1; Histidine phosphatase superfamily (branch 1) (PF00300; HMM-score: 127.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.030877
    • TAT(Tat/SPI): 0.008192
    • LIPO(Sec/SPII): 0.003189
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MLLLAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGIFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL

⊟Experimental data[edit | edit source]

  • experimentally validated: PeptideAtlas
  • protein localization: Cytoplasmic [1]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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