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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1708 [new locus tag: SACOL_RS08720 ]
  • pan locus tag?: SAUPAN004272000
  • symbol: SACOL1708
  • pan gene symbol?: comC
  • synonym:
  • product: type III leader peptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL1708 [new locus tag: SACOL_RS08720 ]
  • symbol: SACOL1708
  • product: type III leader peptidase
  • replicon: chromosome
  • strand: -
  • coordinates: 1737375..1738082
  • length: 708
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    TTGGTAGTATTGTTATCTTATAGTTGCAGTTGTATTTTTAGTTTTCTATATCAATTTATA
    TCTATAGAAGAAACGTCATTTGATTATTTACATAGAAGATCGAAATGTGATTATTGTAAT
    TCGTCACTCAAATGGTATGAATTAATGCCGATTATTAGTTTTTTATTATTAAAAGGGCGA
    TGTCGAAACTGTCGAAAGCGTATTTCCCTAACACATTTCTTAGGGGAAACCTTTGCTTTA
    ATACCTATCGTCTTTATTAAGTATGATTTCACATACGTAAATGCTACGCTATTTATAACT
    ACATATGTTTTTCTGCTTATTTTTACTATGACCGATATCACTTCTTTAATGTTAGATTGT
    CGCTTAATTATAATTTATTGTATCGTTTCTCTCTCGTTAAGTATGATTTATCCAGTAGCT
    TTTATCATTATTAGTATGACCACGCATATATTCTACTTTTTATTTCGGGCATATATTGGT
    TATGGTGACGTTTTACTAATATCTGCACTTTCTTTGTTTTTCCCTCTCCAATTCACTATT
    TATGTCATTTTATTTACATTTGTCATTGCTGGTTTAGTTGCTTTAATTACCATGATATTT
    AAGCCGATTAAACTATTACCCCTTGTTCCATTTATATTTATTTCCTTTTTTATCAATTCA
    CTTTTTTATAATGATATCCATCAATTTTTAGGAGGCGTATATTTTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    708

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL1708 [new locus tag: SACOL_RS08720 ]
  • symbol: SACOL1708
  • description: type III leader peptidase
  • length: 235
  • theoretical pI: 8.36288
  • theoretical MW: 27504
  • GRAVY: 1.0834

⊟Function[edit | edit source]

  • TIGRFAM:
    cxxc_20_cxxc protein (TIGR04104; HMM-score: 17.7)
  • TheSEED  :
    • Late competence protein ComC, processing protease
    DNA Metabolism DNA uptake, competence Gram Positive Competence  Late competence protein ComC, processing protease
    and 1 more
    DNA Metabolism DNA uptake, competence Late competence  Late competence protein ComC, processing protease
  • PFAM:
    no clan defined DiS_P_DiS; Bacterial Peptidase A24 N-terminal domain (PF06750; HMM-score: 69.6)
    and 2 more
    Peptidase_AD (CL0130) Peptidase_A24; Type IV leader peptidase family (PF01478; HMM-score: 15.6)
    Zn_Beta_Ribbon (CL0167) DZR; Double zinc ribbon (PF12773; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.082256
    • TAT(Tat/SPI): 0.004679
    • LIPO(Sec/SPII): 0.017514
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MVVLLSYSCSCIFSFLYQFISIEETSFDYLHRRSKCDYCNSSLKWYELMPIISFLLLKGRCRNCRKRISLTHFLGETFALIPIVFIKYDFTYVNATLFITTYVFLLIFTMTDITSLMLDCRLIIIYCIVSLSLSMIYPVAFIIISMTTHIFYFLFRAYIGYGDVLLISALSLFFPLQFTIYVILFTFVIAGLVALITMIFKPIKLLPLVPFIFISFFINSLFYNDIHQFLGGVYF

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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