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NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1763 [new locus tag: SACOL_RS09015 ]
  • pan locus tag?: SAUPAN004366000
  • symbol: SACOL1763
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL1763 [new locus tag: SACOL_RS09015 ]
  • symbol: SACOL1763
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1802449..1803219
  • length: 771
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGGATTTGAACTTAACGATGATTATAATCATAATTTTATTTGGTTTTATCGCGGCGTTT
    ATAGATTCGGTTGTAGGGGGTGGCGGTTTAATTTCTACGCCAGCATTATTAGCAATCGGT
    CTACCACCATCTGTGGCTTTAGGTACAAATAAATTGGCAAGTTCGTTTGGTTCTTTAACT
    AGTACGATAAAGTTTATAAGGTCCGGTAAAGTGGACTTATATGTTGTTGCCAAATTATTT
    GGTTTTGTATTTTTGGCATCTGCATGTGGCGCATATATTGCAACGATGGTTCCGTCACAA
    ATATTGAAACCTTTAATCATCATTGCACTTTCGTCGGTGTTTATATTCACATTACTTAAA
    AAAGATTGGGGCAATACACGCACGTTTACTCAATTTACATTTAAGAAAGCCATAATATTT
    GCAGCACTTTTTATATTAATCGGCTTTTATGATGGATTTGTAGGTGGGGGAACAGGTTCA
    TTTATGCTTTTTGTATTGTTAGTCTTTGGTTTTGATTTTTTAAGTGCAGCAGGAAATGCT
    AAAGTTTTGAACTTTGCTTCTAATATAGGTGCGCTTGTATTATTTATGGTATTAGGACAA
    GTAGATTATGTAATAGGTTTAATTATGGCTATAAGTATGATTGCTGGGTCATATGCTGGG
    GCTCATTTTGCTATTAAACAAGGTGTTGGTTATGTAAAAGTATTATTTATTATTATTACT
    GCTATTTTAATTTTAAAAAATGCTTTTGATTATATTCAACAATTTGTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    771

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL1763 [new locus tag: SACOL_RS09015 ]
  • symbol: SACOL1763
  • description: hypothetical protein
  • length: 256
  • theoretical pI: 10.0239
  • theoretical MW: 27269.6
  • GRAVY: 1.22344

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED:  
    Putative membrane protein YfcA
  • PFAM:
    LysE (CL0292) TauE; Sulfite exporter TauE/SafE (PF01925; HMM-score: 137.1)

Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.270056
    • TAT(Tat/SPI): 0.005867
    • LIPO(Sec/SPII): 0.038452
  • predicted transmembrane helices (TMHMM): 7

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MDLNLTMIIIIILFGFIAAFIDSVVGGGGLISTPALLAIGLPPSVALGTNKLASSFGSLTSTIKFIRSGKVDLYVVAKLFGFVFLASACGAYIATMVPSQILKPLIIIALSSVFIFTLLKKDWGNTRTFTQFTFKKAIIFAALFILIGFYDGFVGGGTGSFMLFVLLVFGFDFLSAAGNAKVLNFASNIGALVLFMVLGQVDYVIGLIMAISMIAGSYAGAHFAIKQGVGYVKVLFIIITAILILKNAFDYIQQFV

Experimental data[edit | edit source]

  • experimentally validated: PeptideAtlas
    experimental localization: Integral membrane [1]

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

  1. Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
    A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
    PLoS One: 2009, 4(12);e8176
    [PubMed:19997597] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]