Jump to navigation
Jump to search
NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL2242 [new locus tag: SACOL_RS11795 ]
- pan locus tag?: SAUPAN005705000
- symbol: SACOL2242
- pan gene symbol?: pbuG
- synonym:
- product: xanthine/uracil permease
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL2242 [new locus tag: SACOL_RS11795 ]
- symbol: SACOL2242
- product: xanthine/uracil permease
- replicon: chromosome
- strand: -
- coordinates: 2308424..2309758
- length: 1335
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3238467 NCBI
- RefSeq: YP_187052 NCBI
- BioCyc: see SACOL_RS11795
- MicrobesOnline: 913727 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321GTGAAAAACTATTTCCAGTTCGATAAATATGGAACAAACTTTAAAAGAGAAATCTTAGGC
GGTATCACAACTTTCTTATCTATGGCCTATATTTTAGCAGTTAACCCGCAAGTTTTAAGT
TTAGCAGGTGTTAAAGGCGTATCAGAAGATATGAAAATGGACCAAGGTGCCATTTTTGTA
GCGACTGCATTAGCAGCATTTGTAGGCTCGCTATTCATGGGGCTAATAGCTAAATATCCA
ATTGCGTTAGCACCAGGTATGGGATTAAATGCATTCTTTGCATTTACTGTTGTGTTAACC
ATGGGTATTCCTTGGCAAGTTGGTTTAACAGGCGTTTTATTCTCAGGTATATTCTTTGCG
ATATTAACCGTCACAGGGTTTAGGGAAGTTATTATTAATGCAATTCCTTATCAAATGAAG
ATGGCTGTTTCAGCAGGTATAGGATTATTCATTACATTTGTAGGTTTACAAAGTTCGGGT
ATTATAGTTAAAAATGAATCTACATTAGTAACATTGGGACATTTAACTGATCCACCAGTA
CTTTTGGCGATATTCGGTATCGTTATTACAGTTATTTTATATGCAATTAAATTGCCGGGT
TCTATCTTTATCGGTATGATCATCACAGCAATCGTTGGTATGTTCACTGGATTGATTCAA
ATGCCATCTGGTATTGTGGGTAAGATTCCAAGTATTGAACCAACGTTCGGTGCTGCATTT
GAAGCGTTTAAAGACCCAAGTCAATTATTAACGATACAGTTCTTAATTGTTATTTTAACG
TTCTTATTTATTGATTTCTTTGATACAGCTGGTACATTAGTAGCTGTTGCTACTCAAGCA
GGTATTATGAAAGATAATAAATTACCAAGAGCTGGTAGAGCATTGTTCTCAGATTCTTTA
GCTACGATTGTAGGATCAGTTTTTGGAACAACTACAACAACTTCTTATATCGAATCAACT
TCAGGTGTTGCTGTAGGTGCTAGAACAGGATTTGCTAGTATCGTAACAGGTTGTTGTTTC
CTATTAGCGCTGTTCTTTAGTCCGTTAATCGCTGTTGTAACAAGTGCAGTTACGACACCA
GCCTTAGTGGTGGTAGGTGTATTAATGGCTGCAAACTTTGCTGAGATAAACTGGAAAAGT
TTTGAAGTTGCAGTGCCAGCCTTCATTACAATCATTATGATGCCTTTATCATATTCAATT
GCAACTGGTATTGCGTGTGGATTTATTTTCTATCCAATTACAATGCTTATCTCTAAAAAA
CATAAAGAAGTACATCCGATAATGTATGTATTAATGGTACTATTCATTCTGTACTTCATA
TTTGTTCATGGTTAA60
120
180
240
300
360
420
480
540
600
660
720
780
840
900
960
1020
1080
1140
1200
1260
1320
1335
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL2242 [new locus tag: SACOL_RS11795 ]
- symbol: SACOL2242
- description: xanthine/uracil permease
- length: 444
- theoretical pI: 8.72068
- theoretical MW: 47395.5
- GRAVY: 1.05068
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Nucleosides, purines and pyrimidines uracil-xanthine permease (TIGR00801; HMM-score: 13.4)
- TheSEED :
- Hypoxanthine/guanine permease PbuG
- PFAM: APC (CL0062) Xan_ur_permease; Permease family (PF00860; HMM-score: 143.1)and 1 moreno clan defined DUF5464; Family of unknown function (DUF5464) (PF17552; HMM-score: 13.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 13
- LocateP: Multi-transmembrane
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: 0.17
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.198549
- TAT(Tat/SPI): 0.020574
- LIPO(Sec/SPII): 0.006314
- predicted transmembrane helices (TMHMM): 13
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGVKGVSEDMKMDQGAIFVATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSGIIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSIEPTFGAAFEAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIESTSGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSIATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
PLoS One: 2009, 4(12);e8176
[PubMed:19997597] [WorldCat.org] [DOI] (I e) - ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
The Staphylococcus aureus proteome.
Int J Med Microbiol: 2014, 304(2);110-20
[PubMed:24439828] [WorldCat.org] [DOI] (I p)