PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus COL
• locus tag: SACOL_RS04605 [old locus tag: SACOL0897 ]
• pan locus tag^?: SAUPAN002859000
• symbol: SACOL_RS04605
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SACOL_RS04605 [old locus tag: SACOL0897 ]
• symbol: SACOL_RS04605
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 909954..911411
• length: 1458
• essential: unknown

⊟Accession numbers

• Location: NC_002951 (909954..911411) NCBI
• BioCyc: SACOL_RS04605 BioCyc
• MicrobesOnline: see SACOL0897

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  1441
  
  TTGGAAGATGTTACAAACGAAGAAGTATTTGAAATGATTGATAGCAGAACCGGTGTTTTA
  AATGCTAATGATTGGAAAAGTCAATTAAGGCGTTCTGCTACTACACAAGCATTGAAAAAA
  ACGACTACAAATGCTGAAATCATATTGTGTAATGATGAGAGTTTAAAAGGGCTAGTACAA
  TATGACGCTTTTGAAAAAGTAACCAAACTGAAACGTCTACCGTATTGGAGGTCAAAAGGA
  GATACGAATTATTATTGGGCTGATATAGATACCACACATGTGATTTCACATATTGATAAA
  TTGTATAATGTGCAGTTTAGCCGTGATCTTATTGATACTGTAATTGAAAAGGAAGCTTAT
  CAAAATAGATTTCACCCTATTAAATCGATGATTGAATCTAAATCATGGGACGGAATCAAA
  AGAATTGAAACGCTCTTCATTGATTATTTAGGTGCTGAAGATAACCACTATAATAGAGAA
  GTTACAAAAAAATGGATGATGGGCGCAGTTGCTAGAATCTATCAGCCAGGTATTAAATAT
  GATTCCATGATTATTTTATATGGTGGTCAAGGTGTTGGAAAATCTACGGCAGTGAGTAAA
  TTGGGAGGTCATTGGTATAACCAAAGTATTAAAACGTTTAAAGGTGATGAGGTCTATAAG
  AAATTGCAGGGTTCTTGGATATGTGAAATTGAAGAACTGTCGGCATTTCAAAAGTCTACT
  ATTGAAGATATTAAGGGGTTTATAAGTGCTATTGTAGATATTTATAGAGCTTCGTATGGT
  AAACGAACAGAGCGTCATCCTAGACAGTGTGTGTTTGTAGGGACAACCAATAACTATGAG
  TTTTTAAAAGACCAAACAGGCAATCGTCGTTTTTTCCCTATTACGACAGATAAAAATAAA
  GCAACTAAAAGCCCGTTTGACGATCTAACACCAGATGTTGTGCAACAAATGTTTGCTGAA
  GCTAAAGTATATTTTGATGAGGATCCGACGGATAAAGCATTGTTATTAGATAAAGAAGCG
  AGTGAGATGGCTTTAAAAGTCCAAGAAGCTCATTCTGAAAAAGATGCTTTAGTTGGAGAA
  ATAGAAGAATTCCTTGAACGTCCTATTCCGTCAGACTATTGGTATAGAACGTTAGAAGAA
  AAAAGAGTGTCTGCGCATGATGTTATAGACCAAGACTATATTAAATTATATGGTGATGGT
  AAATTGATTGAATTACCGAATACAAAACCAGGTGCTTATGTATGGCGTGACAAGGTATGT
  AGCATGGAAATTTGGAAAGTGATGATGAAACGAGATGACCAACCACAACAACACCATTTA
  AGAAAAATTGATAAAGCGTTAAGAAATACAAATTATTGTGACACTGTGAAAAAGCAAACG
  CGATATGGTGAAGGTATTGGTAAGCAATATGGCTTTAGTGTAGATTTAGCTTCTTATTAT
  AAGAATCTTAAAGTTTAA
  60
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  1458
  

⊟Protein

⊟General

• locus tag: SACOL_RS04605 [old locus tag: SACOL0897 ]
• symbol: SACOL_RS04605
• description: hypothetical protein
• length: 485
• theoretical pI: 7.05745
• theoretical MW: 56364.5
• GRAVY: -0.661856

⊟Function

• TIGRFAM:
  Cellular processes Cellular processes Chemotaxis and motility flagellar biosynthesis protein FlhF (TIGR03499; HMM-score: 16.8)
• TheSEED: see SACOL0897
• PFAM:
  P-loop_NTPase (CL0023) VapE-like_dom; Virulence-associated protein E-like domain (PF05272; HMM-score: 259.3)
  and 9 more
  DUF5906; Family of unknown function (DUF5906) (PF19263; HMM-score: 32.5)
  RNA_helicase; RNA helicase (PF00910; HMM-score: 18.5)
  AAA_28; AAA domain (PF13521; HMM-score: 15)
  AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 14.6)
  AAA_24; AAA domain (PF13479; HMM-score: 14.3)
  AAA_14; AAA domain (PF13173; HMM-score: 12.3)
  SRP54; SRP54-type protein, GTPase domain (PF00448; HMM-score: 11.7)
  AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 11.7)
  RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 11)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9442
  • Cytoplasmic Membrane Score: 0.0018
  • Cell wall & surface Score: 0.0003
  • Extracellular Score: 0.0538
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.012039
  • TAT(Tat/SPI): 0.00936
  • LIPO(Sec/SPII): 0.000837
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446312600 NCBI
• RefSeq: WP_000390455 NCBI
• UniProt: see SACOL0897

⊟Protein sequence

• MEDVTNEEVFEMIDSRTGVLNANDWKSQLRRSATTQALKKTTTNAEIILCNDESLKGLVQYDAFEKVTKLKRLPYWRSKGDTNYYWADIDTTHVISHIDKLYNVQFSRDLIDTVIEKEAYQNRFHPIKSMIESKSWDGIKRIETLFIDYLGAEDNHYNREVTKKWMMGAVARIYQPGIKYDSMIILYGGQGVGKSTAVSKLGGHWYNQSIKTFKGDEVYKKLQGSWICEIEELSAFQKSTIEDIKGFISAIVDIYRASYGKRTERHPRQCVFVGTTNNYEFLKDQTGNRRFFPITTDKNKATKSPFDDLTPDVVQQMFAEAKVYFDEDPTDKALLLDKEASEMALKVQEAHSEKDALVGEIEEFLERPIPSDYWYRTLEEKRVSAHDVIDQDYIKLYGDGKLIELPNTKPGAYVWRDKVCSMEIWKVMMKRDDQPQQHHLRKIDKALRNTNYCDTVKKQTRYGEGIGKQYGFSVDLASYYKNLKV

⊟Experimental data

• experimentally validated:
• protein localization: see SACOL0897
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications