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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS11945 [old locus tag: SACOL2272 ]
  • pan locus tag?: SAUPAN005740000
  • symbol: SACOL_RS11945
  • pan gene symbol?: modA
  • synonym:
  • product: molybdate ABC transporter substrate-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL_RS11945 [old locus tag: SACOL2272 ]
  • symbol: SACOL_RS11945
  • product: molybdate ABC transporter substrate-binding protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2333040..2333822
  • length: 783
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002951 (2333040..2333822) NCBI
  • BioCyc: SACOL_RS11945 BioCyc
  • MicrobesOnline: see SACOL2272

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAAATTGAAACGTTTATTTGCTGTTGTGATTGCAATGCTTTTAGTATTAGCTGGTTGC
    TCTAATTCTAACGATAATAATGAAAGTAAAAAAGATGACGCAGACAATGGTAAGAAACAA
    GAGATTCAAGTTGCAGCGGCAGCAAGTTTAACAGATGTAACCAAGAAATTAGCTTCAGAA
    TTTAAAAAAGAGCATAAAAATGCTGATATTAAATTTAACTATGGTGGATCAGGGGCATTA
    AGAAAACAAATTGAATCAGGCGCACCTGTTGACGTATTTATGTCTGCAAATACTAAAGAT
    GTAGATGCATTAAAAGACAAGAATAAAGCGCATGATACATATAAATATGCGAAAAATAGT
    CTAGTATTAATTGGTGATAAAGATTCAAATTACACTTCAGTAAAAGACTTAAAAGACAAT
    GATAAATTAGCATTAGGTGAAGTGAAAACTGTACCAGCAGGAAAATATGCGAAACAGTAT
    TTAGATAACAATAACTTATTTAAAGAAGTCGAAAGTAAAATCGTTTATGCTAAAGATGTA
    AAACAAGTATTAAATTATGTTGAAAAGGGTAATGCGAAACAAGGTTTTGTGTATAAAACT
    GACTTATATAAACAAAATAAAAAAATTGATACTGTAAAAGTAATTAAAGAAGTAGAACTT
    AAGAAGCCAATCACATACGAAGCTGGTGCTACATCAGATAGTAAATTAGCAAAAGAGTGG
    ATGGAATTCTTAAAATCAGATAAAGCTAAAGAAATACTAAAAGAATACCACTTTGCAGCA
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    783

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL_RS11945 [old locus tag: SACOL2272 ]
  • symbol: SACOL_RS11945
  • description: molybdate ABC transporter substrate-binding protein
  • length: 260
  • theoretical pI: 9.79443
  • theoretical MW: 29051
  • GRAVY: -0.637308

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, periplasmic molybdate-binding protein (TIGR01256; HMM-score: 184.5)
    and 3 more
    Metabolism Transport and binding proteins Anions phosphate binding protein (TIGR02136; HMM-score: 35)
    tungstate ABC transporter binding protein WtpA (TIGR03730; HMM-score: 34.9)
    Cellular processes Cellular processes Sporulation and germination sporulation lipoprotein, YhcN/YlaJ family (TIGR02898; HMM-score: 15)
  • TheSEED: see SACOL2272
  • PFAM:
    PBP (CL0177) SBP_bac_11; Bacterial extracellular solute-binding protein (PF13531; HMM-score: 141.2)
    and 5 more
    SBP_bac_1; Bacterial extracellular solute-binding protein (PF01547; HMM-score: 53.3)
    PBP_like_2; PBP superfamily domain (PF12849; HMM-score: 25.3)
    no clan defined Pilus_CpaD; Pilus biogenesis CpaD protein (pilus_cpaD) (PF09476; HMM-score: 17.3)
    LppaM (CL0421) LPAM_1; Prokaryotic membrane lipoprotein lipid attachment site (PF08139; HMM-score: 13)
    no clan defined Tox-REase-7; Restriction endonuclease fold toxin 7 (PF15649; HMM-score: 7.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helices: 0
  • LocateP:
  • SignalP: Signal peptide LIPO(Sec/SPII) length 19 aa
    • SP(Sec/SPI): 0.00027
    • TAT(Tat/SPI): 0.00004
    • LIPO(Sec/SPII): 0.999568
    • Cleavage Site: CS pos: 19-20. LAG-CS. Pr: 1.0000
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKLKRLFAVVIAMLLVLAGCSNSNDNNESKKDDADNGKKQEIQVAAAASLTDVTKKLASEFKKEHKNADIKFNYGGSGALRKQIESGAPVDVFMSANTKDVDALKDKNKAHDTYKYAKNSLVLIGDKDSNYTSVKDLKDNDKLALGEVKTVPAGKYAKQYLDNNNLFKEVESKIVYAKDVKQVLNYVEKGNAKQGFVYKTDLYKQNKKIDTVKVIKEVELKKPITYEAGATSDSKLAKEWMEFLKSDKAKEILKEYHFAA

⊟Experimental data[edit | edit source]

  • experimentally validated: see SACOL2272
  • protein localization: see SACOL2272
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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