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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 03-AUG-2016

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_02196
  • pan locus tag?: SAUPAN001535000
  • symbol: SAOUHSC_02196
  • pan gene symbol?: —
  • synonym:
  • product: phage terminase large subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAOUHSC_02196
  • symbol: SAOUHSC_02196
  • product: phage terminase large subunit
  • replicon: chromosome
  • strand: -
  • coordinates: 2055385..2057079
  • length: 1695
  • essential: no DEG

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    ATGACTGATTATGTTACTAAATACGCAAAAAAGGTAGTTTCAGGAGAAATTTTGGCAAGT
    TTGAAGAATATTCAAGTATGTAAACGTCACCTATCTTTTATGGAGAACCCGCCGAATGGT
    TGCCATTGGGATAATCATTTGTCTAACAAAGCAATTAAATTTGTGGAAATGCTTCCAGAC
    CCTAAAACAAACCAGCCCATGCCTCTTATGGAGTTTCAGAAATTCATTGTTGGGAGCTTA
    TACGGCTGGCGTAGAGGTCAATACAGAATGTTTACTAAAGCTTATATAAGTATGGCTAGA
    AAACAAGGTAAGTCTCTAATCGTATCGGGAATGTCCGTTAACGAACTGTTGTTTGGACAA
    TACCCTAAATTTAATAGACAAATTTATGTAGCTTCATCTACTTATAAGCAAGCGCAAACA
    ATATTCAAGATGGCAAGCCAACAAGTAAACCTAATGCGAAGTAAAAGCAAGTTTATCCGT
    GAAAAAACAGACGTAAGAAAGACAGACATTGAAGATGTATTAAGTAGTTCAGTGTTTGCA
    CCTCTTTCCAATAACCCAGATGCGGTTGATGGTAAAGATCCTACAGTTGCTATTTTGGAC
    GAATTGGCAAGTATGCCTGATGATGAGATGTACTCAAGGTTTAAAACAGGTATGACATTA
    CAAAAAAATCCTTTAACCCTACTTGTTTCAACGGCCGGAGACAATTTAAATAGTCAAATG
    TACCAAGAGTATAAGTATATTAAACGTATTTTAAATGAAGAAGTAAGAGCTGATAATTAC
    TTTGTATATTGTGCTGAAATGGATTCACAAGAAGAAGTTCAAGATGAAACAAAGTGGATT
    AAAGCAATGCCGCTTTTAGAATCAAAAGAACATAGAAAAACTATACTTCAAAATGTAAAA
    GCTGATATACAAGACGAATTAGAAAAAGGGACATCATATCATAAGATTTTGATTAAAAAC
    TTCAATTTATGGCAAGCGCAAAGAGAAGATAGCTTGCTAGATATTTCAGATTGGGAACAA
    GTAATAACGCCTATGCCTAATATCAATGGTAAAGATGTGTATATAGGTGTCGACTTATCG
    AGATTGGATGACTTAACATCTGTAGGGTTTATTTTCCCTAACGACGATAAAAAAGTGTTT
    TTACATAGTCATTCTTTCATTGGATTAAGAACAAACTTAGAACAAAAATCTAAGAGAGAC
    AAAATAAATTATGAATTAGCGATTGAACGTGGCGAAGCTGAGACTACACAATCAGATAGC
    GGCATGATTGATTATAAACAAGTTATCGATTTTATAGTGAAATTTATAACGACGCATGAC
    CTGAATGTACAGGCTGTTTGCTATGACCCTTGGAATGCGCAAAGTTTTATAACAACAATC
    GAATCAATGGCTTTAGATTGGCCACTCATTGAAGTGGGACAAAGTTTTAAGGCGTTATCA
    CAATCTATTAAAGAATTTAGAATGTGGGTTGCAGATGAAAGAATACAGCATAACGATAAT
    ATGTTACTTACAACATCAGTTAATAATGCCGTTTTGATTCGTGACGGAGAAGACAATGTG
    AAAATAAATAAAAAAATGAATCGTCAAAAAATAGATCCGATTATTTCGATTATCACAGCT
    TTCACTGAAGCTAGAATGCACGAATTCCAAGAAAATTGGACGGAGAAATATGAAAGCGAA
    GAATTCGGATTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1695

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAOUHSC_02196
  • symbol: SAOUHSC_02196
  • description: phage terminase large subunit
  • length: 564
  • theoretical pI: 6.06171
  • theoretical MW: 65290.1
  • GRAVY: -0.487057

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Phage terminase large subunit
  • PFAM:
    P-loop_NTPase (CL0023) Terminase_1; Phage Terminase (PF03354; HMM-score: 780.9)
    and 3 more
    Terminase_6; Terminase-like family (PF03237; HMM-score: 21.6)
    Helicase_RecD; Helicase (PF05127; HMM-score: 20.8)
    no clan defined PurL_C; Phosphoribosylformylglycinamidine synthase II C-terminus (PF16904; HMM-score: 9.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007295
    • TAT(Tat/SPI): 0.000273
    • LIPO(Sec/SPII): 0.002101
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTDYVTKYAKKVVSGEILASLKNIQVCKRHLSFMENPPNGCHWDNHLSNKAIKFVEMLPDPKTNQPMPLMEFQKFIVGSLYGWRRGQYRMFTKAYISMARKQGKSLIVSGMSVNELLFGQYPKFNRQIYVASSTYKQAQTIFKMASQQVNLMRSKSKFIREKTDVRKTDIEDVLSSSVFAPLSNNPDAVDGKDPTVAILDELASMPDDEMYSRFKTGMTLQKNPLTLLVSTAGDNLNSQMYQEYKYIKRILNEEVRADNYFVYCAEMDSQEEVQDETKWIKAMPLLESKEHRKTILQNVKADIQDELEKGTSYHKILIKNFNLWQAQREDSLLDISDWEQVITPMPNINGKDVYIGVDLSRLDDLTSVGFIFPNDDKKVFLHSHSFIGLRTNLEQKSKRDKINYELAIERGEAETTQSDSGMIDYKQVIDFIVKFITTHDLNVQAVCYDPWNAQSFITTIESMALDWPLIEVGQSFKALSQSIKEFRMWVADERIQHNDNMLLTTSVNNAVLIRDGEDNVKINKKMNRQKIDPIISIITAFTEARMHEFQENWTEKYESEEFGF

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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