PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN000486000
• symbol^?: cstB
• synonym:
• description^?: MBL fold metallo-hydrolase

  descriptions from strain specific annotations:

  • MBL fold metallo-hydrolase
  • metallo-beta-lactamase
  • metallo-beta-lactamase superfamily protein
  • beta-lactamase domain-containing protein
  • hydroxyacylglutathione hydrolase
  • Metal-dependent hydrolase with rhodanese-homology domain (RHOD)
  • metallo-beta-lactamase family protein
• strand^?: +
• coordinates^?: 520267..522435
• synteny block^?: BlockID0002160
• occurrence^?: in 58% of 33 strains

⊟Orthologs

COL:
SACOL0064
N315:
SA0083
NCTC8325:
SAOUHSC_00036
Newman:
NWMN_0028
USA300_FPR3757:
SAUSA300_0086
04-02981:
SA2981_0087
08BA02176:
—
11819-97:
—
6850:
—
71193:
—
ECT-R 2:
ECTR2_45
ED133:
SAOV_0039
ED98:
SAAV_0035
HO 5096 0412:
—
JH1:
SaurJH1_0076
JH9:
SaurJH9_0074
JKD6008:
—
JKD6159:
—
LGA251:
SARLGA251_00660
M013:
—
MRSA252:
—
MSHR1132:
—
MSSA476:
SAS0057
Mu3:
SAHV_0086
Mu50:
SAV0087
MW2:
MW0057
RF122:
SAB0031
ST398:
—
T0131:
—
TCH60:
—
TW20:
—
USA300_TCH1516:
USA300HOU_0093
VC40:
SAVC_00150

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHAD
  N315            MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHAD
  NCTC8325        MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHAD
  Newman          MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHAD
  USA300_FPR3757  MFFKQFYDNHLSQASYLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHAD
                  ************************************************************
  
  COL             FASGIRDVAKRLNANIYVSGEGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHT
  N315            FASGIRDVAKRLNANIYVSGEGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHT
  NCTC8325        FASGIRDVAKRLNANIYVSGEGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHT
  Newman          FASGIRDVAKRLNANIYVSGEGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHT
  USA300_FPR3757  FASGIRDVAKRLNANIYVSGEGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHT
                  ************************************************************
  
  COL             PESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEKSVQIKGSTEISAKQMYESVQ
  N315            PESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEKSVQIKGSTEISAKQMYESVQ
  NCTC8325        PESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEKSVQIKGSTEISAKQMYESVQ
  Newman          PESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEKSVQIKGSTEISAKQMYESVQ
  USA300_FPR3757  PESISFLLTDLGGGSSVPMGLFSGDFIFVGDIGRPDLLEKSVQIKGSTEISAKQMYESVQ
                  ************************************************************
  
  COL             NIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKINNWAFNEIDETKFIESLTSNQP
  N315            NIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKINNWAFNEIDETKFIESLTSNQP
  NCTC8325        NIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKINNWAFNEIDETKFIESLTSNQP
  Newman          NIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKINNWAFNEIDETKFIESLTSNQP
  USA300_FPR3757  NIKNLPDYVQIWPGHGAGSPCGKALGAIPISTIGYEKINNWAFNEIDETKFIESLTSNQP
                  ************************************************************
  
  COL             APPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAFDLRSKEAFHGGHTKGTINIPYNKN
  N315            APPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAFDLRSKEAFHGGHTKGTINIPYNKN
  NCTC8325        APPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAFDLRSKEAFHGGHTKGTINIPYNKN
  Newman          APPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAFDLRSKEAFHGGHTKGTINIPYNKN
  USA300_FPR3757  APPHHFAQMKQVNQFGMNLYQSYDVYPSLDNKRVAFDLRSKEAFHGGHTKGTINIPYNKN
                  ************************************************************
  
  COL             FINQIGWYLDFEKDIDLIGDKSTVEKAKHTLQLIGFDKVAGYRLPKSGISTQSVHSADMT
  N315            FINQIGWYLDFEKDIDLIGDKSTVEKAKHTLQLIGFDKVAGYRLPKSGISTQSVHSADMT
  NCTC8325        FINQIGWYLDFEKDIDVIGDKSTVEKAKHTLQLIGFDKVAGYRLPKSGISTQSVHSADMT
  Newman          FINQIGWYLDFEKDIDLIGDKSTVEKAKHTLQLIGFDKVAGYRLPKSGISTQSVHSADMT
  USA300_FPR3757  FINQIGWYLDFEKDIDLIGDKSTVEKAKHTLQLIGFDKVAGYRLPKSGISTQSVHSADMT
                  ****************:*******************************************
  
  COL             GKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLLNENIPFNKEDKIYVHCQSGVRSSIAVGI
  N315            GKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLLNENIPFNKEDKIYVHCQSGVRSSIAVGI
  NCTC8325        GKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLLNENIPFNKEDKIYVHCQSGVRSSIAVGI
  Newman          GKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLLNENIPFNKEDKIYVHCQSGVRSSIAVGI
  USA300_FPR3757  GKEEHVLDVRNDEEWNNGHLDQAVNIPHGKLLNENIPFNKEDKIYVHCQSGVRSSIAVGI
                  ************************************************************
  
  COL             LESKGFENVVNIREGYQDFPESLK
  N315            LESKGFENVVNIREGYQDFPESLK
  NCTC8325        LESKGFENVVNIREGYQDFPESLK
  Newman          LESKGFENVVNIREGYQDFPESLK
  USA300_FPR3757  LESKGFENVVNIREGYQDFPESLK
                  ************************