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PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

Summary[edit | edit source]

  • pan ID?: SAUPAN000824000
  • symbol?:
  • synonym:
  • description?: ABC transporter ATP-binding protein

      descriptions from strain specific annotations:

    • ABC transporter ATP-binding protein
    • nickel/peptide ABC transporter ATP-binding protein
  • strand?: +
  • coordinates?: 1059666..1060433
  • synteny block?: BlockID0003930
  • occurrence?: in 6% of 34 strains

oppDA (oppDACME): nickel/oligopeptide ABC transporter ATP-binding protein ACME-OppD [1]

• this version of oppD is found in the Arginine Catabolic Mobile Element (ACME) that is sometimes found alongside the SCCmec cassette, particularly in USA300 MRSA strains. It encodes an opp3-like nickel/oligopeptide ABC transporter that, due to similarities to opp1/2 transporters, is more likely to transport metals than peptides, although substrate specificity has not yet been established.

Orthologs[edit | edit source]

    COL:
    N315:
    NCTC8325:
    Newman:
    USA300_FPR3757:
    JSNZ:
    04-02981:
    08BA02176:
    11819-97:
    6850:
    71193:
    ECT-R 2:
    ED133:
    ED98:
    HO 5096 0412:
    JH1:
    JH9:
    JKD6008:
    JKD6159:
    LGA251:
    M013:
    MRSA252:
    MSHR1132:
    MSSA476:
    Mu3:
    Mu50:
    MW2:
    RF122:
    ST398:
    T0131:
    TCH60:
    TW20:
    USA300_TCH1516:
    USA300HOU_0081
    VC40:

Genome Viewer[edit | edit source]

Alignments[edit | edit source]

  • alignment of orthologues:

  1. Dongliang Yu, Borui Pi, Meihong Yu, Yanfei Wang, Zhi Ruan, Ye Feng, Yunsong Yu
    Diversity and evolution of oligopeptide permease systems in staphylococcal species.
    Genomics: 2014, 104(1);8-13
    [PubMed:24793159] [WorldCat.org] [DOI] (I p)
    Chunguang Liang, Dominik Schaack, Mugdha Srivastava, Shishir K Gupta, Edita Sarukhanyan, Anne Giese, Martin Pagels, Natalie Romanov, Jan Pané-Farré, Stephan Fuchs, Thomas Dandekar
    A Staphylococcus aureus Proteome Overview: Shared and Specific Proteins and Protein Complexes from Representative Strains of All Three Clades.
    Proteomes: 2016, 4(1);
    [PubMed:28248218] [WorldCat.org] [DOI] (P e)
    Imran Khan, Sandy J MacDonald, Sigurbjörn Markússon, Paige J Kies, Cristina Kraemer-Zimpel, Callum Robson, Joanne L Parker, Simon Newstead, Dave Boucher, Neal D Hammer, Marjan Van Der Woude, Gavin H Thomas
    Defined roles for the Staphylococcus aureus POT transporter DtpT in di/tripeptide uptake and glutathione utilisation inside human macrophages.
    PLoS Pathog: 2025, 21(9);e1013535
    [PubMed:41004555] [WorldCat.org] [DOI] (I e)