Jump to navigation
Jump to search
⊟Summary[edit | edit source]
- pan ID?: SAUPAN000859000
- symbol?: —
- synonym:
- description?: tandem-type lipoprotein
- tandem-type lipoprotein
- staphylococcal tandem lipoprotein
- tandem lipoprotein
- lipoprotein
- pseudogene
- putative lipoprotein
- putative lipoprotein, truncated
- staphylococcus tandem lipoproteins family protein
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 1128174..1128945
- synteny block?: BlockID0004200
- occurrence?: in 85% of 33 strains
csa1B : tandem conserved staphylococcal antigen 1B [1]
• A crystal structure is available: 4BIG
• binds extracellular DNA as a lipoprotein during biofilm formation
• exact number of tandem repeats varies and can expand or contract over the course of an infection
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0097
08BA02176:
—
11819-97:
MS7_0091
6850:
RSAU_000051
71193:
—
ECT-R 2:
ECTR2_54
ED133:
SAOV_0050
ED98:
SAAV_0045
HO 5096 0412:
SAEMRSA15_00680
JH1:
SaurJH1_0088
JH9:
SaurJH9_0085
JKD6008:
SAA6008_00081
JKD6159:
SAA6159_00080
LGA251:
SARLGA251_00760
M013:
—
MRSA252:
SAR0106
MSHR1132:
—
MSSA476:
SAS0073
Mu3:
SAHV_0096
Mu50:
SAV0097
MW2:
MW0072
RF122:
SAB0039
ST398:
—
T0131:
SAT0131_00083
TCH60:
HMPREF0772_10394
TW20:
SATW20_01150
USA300_TCH1516:
USA300HOU_0110
VC40:
SAVC_00235
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MIKRVNKLVLGISLLFLVISITAGCGMGKEAEIKKSFEKTLSMYPIKNLEDLYDKEGYRD
N315 MIKRVNKLVLGISFLFLIISIFAGCGTGKEAEIKKSFEKTLSMYPIKNLEDLYDKEGYRD
NCTC8325 MIKRVNKLVLGISLLFLVISITAGCGMGKEAEIKKSFEKTLSMYPIKNLEDLYDKEGYRD
Newman MIKRVNKLVLGISLLFLVISITAGCGMGKEAEIKKSFEKTLSMYPIKNLEDLYDKEGYRD
USA300_FPR3757 MIKRVNKLVLGISLLFLVISITAGCGMGKEAEIKKSFEKTLSMYPIKNLEDLYDKEGYRD
*************:***:*** **** *********************************
COL DQFDKNDKGTWIVNSQMAIQNKGEALKIKGMLLKIDRNTRSAKGFYYTNEIKTEKYEVAQ
N315 DQFDKNDKGTWIVRSSMSIQSNGKDMNIKGMVLYMNRNTRTTNGYYYVDVIEREDKGIHR
NCTC8325 DQFDKNDKGTWIVNSQMAIQNKGEALKIKGMLLKIDRNTRSAKGFYYTNEIKTEKYEVAQ
Newman DQFDKNDKGTWIVNSQMAIQNKGEALKIKGMLLKIDRNTRSAKGFYYTNEIKTEKYEVAQ
USA300_FPR3757 DQFDKNDKGTWIVNSQMAIQNKGEALKIKGMLLKIDRNTRSAKGFYYTNEIKTEKYEVAQ
*************.*.*:**.:*: ::****:* ::****:::*:**.: *: *. : :
COL DNQKKYPVKMINNKFISTEEVKEENIKKEIENFKFFAQYSNFKDLMNYKDGDISYNPEVP
N315 DNEKRYPVKMVDNKIIPTKEIKDEKIKKEIENFKFFVQYGDFKDLSKYKDGDISYNPEVP
NCTC8325 DNQKKYPVKMINNKFISTEEVKEENIKKEIENFKFFAQYSNFKDLMNYKDGDISYNPEVP
Newman DNQKKYPVKMINNKFISTEEVKEENIKKEIENFKFFAQYSNFKDLMNYKDGDISYNPEVP
USA300_FPR3757 DNQKKYPVKMINNKFISTEEVKEENIKKEIENFKFFAQYSNFKDLMNYKDGDISYNPEVP
**:*:*****::**:*.*:*:*:*:***********.**.:**** :*************
COL SYSAQYQLTNDDYNVKQLRKRYDIPTNKAPKLLLKGTGNLKGSSVGYKKIEFTFLENKNE
N315 SYSAKYQLTNDDYNVKQLRKRYNIPTNKAPKLLLKGTGNLKGSSIGYKKIEFTFVEKKGE
NCTC8325 SYSAQYQLTNDDYNVKQLRKRYDIPTNKAPKLLLKGTGNLKGSSVGYKKIEFTFLENKNE
Newman SYSAQYQLTNDDYNVKQLRKRYDIPTNKAPKLLLKGTGNLKGSSVGYKKIEFTFLENKNE
USA300_FPR3757 SYSAQYQLTNDDYNVKQLRKRYDIPTNKAPKLLLKGTGNLKGSSVGYKKIEFTFLENKNE
****:*****************:*********************:*********:*:*.*
COL NIYFTDSLHLEPSEDK
N315 NIYFSDGLHFNPSEDK
NCTC8325 NIYFTDSLHLEPSEDK
Newman NIYFTDSLHLEPSEDK
USA300_FPR3757 NIYFTDSLHLEPSEDK
****:*.**::*****
- ↑ Darya Belikova, Angelika Jochim, Jeffrey Power, Matthew T G Holden, Simon Heilbronner
"Gene accordions" cause genotypic and phenotypic heterogeneity in clonal populations of Staphylococcus aureus.
Nat Commun: 2020, 11(1);3526
[PubMed:32665571] [WorldCat.org] [DOI] (I e)Christina Schluepen, Enrico Malito, Ambra Marongiu, Markus Schirle, Elisabeth McWhinnie, Paola Lo Surdo, Marco Biancucci, Fabiana Falugi, Vincenzo Nardi-Dei, Sara Marchi, Maria Rita Fontana, Benedetta Lombardi, Maria Grazia De Falco, C Daniela Rinaudo, Glen Spraggon, Mikkel Nissum, Fabio Bagnoli, Guido Grandi, Matthew J Bottomley, Sabrina Liberatori
Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus.
Biochem J: 2013, 455(3);273-84
[PubMed:23895222] [WorldCat.org] [DOI] (I p)Jeffrey S Kavanaugh, Caralyn E Flack, Jessica Lister, Erica B Ricker, Carolyn B Ibberson, Christian Jenul, Derek E Moormeier, Elizabeth A Delmain, Kenneth W Bayles, Alexander R Horswill
Identification of Extracellular DNA-Binding Proteins in the Biofilm Matrix.
mBio: 2019, 10(3);
[PubMed:31239382] [WorldCat.org] [DOI] (I e)