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⊟Summary[edit | edit source]
- pan ID?: SAUPAN000861000
- symbol?: —
- synonym:
- description?: tandem-type lipoprotein
- tandem-type lipoprotein
- tandem lipoprotein
- Membrane lipoprotein
- putative lipoprotein
- staphylococcus tandem lipoproteins family protein
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 1128177..1153528
- synteny block?: BlockID0004220
- occurrence?: in 59% of 34 strains
csa1D : tandem conserved staphylococcal antigen 1D [1]
• binds extracellular DNA as a lipoprotein during biofilm formation
• exact number of tandem repeats varies and can expand or contract over the course of an infection
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0100
08BA02176:
C248_0090
11819-97:
—
6850:
—
71193:
ST398NM01_2805
ECT-R 2:
ECTR2_57
ED133:
—
ED98:
SAAV_0068
HO 5096 0412:
SAEMRSA15_00690
JH1:
SaurJH1_0091
JH9:
SaurJH9_0088
JKD6008:
—
JKD6159:
—
JSNZ:
JSNZ_000044
LGA251:
—
M013:
M013TW_0089
MRSA252:
—
MSHR1132:
—
MSSA476:
—
Mu3:
SAHV_0099
Mu50:
SAV0100
MW2:
—
RF122:
—
ST398:
SAPIG0114
T0131:
—
TCH60:
—
TW20:
—
USA300_TCH1516:
USA300HOU_0112
VC40:
SAVC_00245
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MKRLNKLVLYISFLILVISFTAGCGIGKEAEVKKSFEKTLSMYPIKNLEDLYDKEGYRDD
N315 MKRLNKLVLYISFLILVISFTAGCGMGKEAEIKKSFEKTLSMYPIKNLEDLYDKEGYRDD
NCTC8325 MKRLNKLVLYISFLILVISFTAGCGIGKEAEVKKSFEKTLSMYPIKNLEDLYDKEGYRDD
Newman MKRLNKLVLYISFLILVISFTAGCGIGKEAEVKKSFEKTLSMYPIKNLEDLYDKEGYRDD
USA300_FPR3757 MKRLNKLVLYISFLILVISFTAGCGIGKEAEVKKSFEKTLSMYPIKNLEDLYDKEGYRDD
*************************:*****:****************************
COL EFDKNDKGTWIIGSEMVVQPKGERMKSKGMVLYMNRNTKTTTGKYIVSETLHDEDGRPKS
N315 QFDKNDKGTWIINSEMVVQPKGERMKSKGMVLYMNRNTKTTTGKYIVSETLHDEDGRPKS
NCTC8325 EFDKNDKGTWIIGSEMVVQPKGERMKSKGMVLYMNRNTKTTTGKYIVSETLHDEDGRPKS
Newman EFDKNDKGTWIIGSEMVVQPKGERMKSKGMVLYMNRNTKTTTGKYIVSETLHDEDGRPKS
USA300_FPR3757 EFDKNDKGTWIIGSEMVVQPKGERMKSKGMVLYMNRNTKTTTGKYIVSETLHDEDGRPKS
:***********.***********************************************
COL KDKEYPVKMVDNKIIPTKGIKDENIKKEIENFKFFAQYGSFKDLSKYKDGDISYNPEVPS
N315 KDKEYPVKMVDNKIIPTKGIKDENIKKEIENFKFFAQYGSFKDLSKYKDGDISYNPEVPS
NCTC8325 KDKEYPVKMVDNKIIPTKGIKDENIKKEIENFKFFAQYGSFKDLSKYKDGDISYNPEVPS
Newman KDKEYPVKMVDNKIIPTKGIKDENIKKEIENFKFFAQYGSFKDLSKYKDGDISYNPEVPS
USA300_FPR3757 KDKEYPVKMVDNKIIPTKGIKDENIKKEIENFKFFAQYGSFKDLSKYKDGDISYNPEVPS
************************************************************
COL YSAKYQLTNDDYNVKQLRKRYKIPTNKAPKLLLKGSGDLKGSSVGYKDIEFTFVEKKGEN
N315 YSAKYQLTNDDYNVKQLRKRYKIPTNKAPKLLLKGSGDLKGSSVGYKDIEFTFVEKKGEN
NCTC8325 YSAKYQLTNDDYNVKQLRKRYKIPTNKAPKLLLKGSGDLKGSSVGYKDIEFTFVEKKGEN
Newman YSAKYQLTNDDYNVKQLRKRYKIPTNKAPKLLLKGSGDLKGSSVGYKDIEFTFVEKKGEN
USA300_FPR3757 YSAKYQLTNDDYNVKQLRKRYKIPTNKAPKLLLKGSGDLKGSSVGYKDIEFTFVEKKGEN
************************************************************
COL TFFTDSLHLEPSEDK
N315 TFFTDSLHLEPSEDK
NCTC8325 TFFTDSLHLEPSEDK
Newman TFFTDSLHLEPSEDK
USA300_FPR3757 TFFTDSLHLEPSEDK
***************
- ↑ Darya Belikova, Angelika Jochim, Jeffrey Power, Matthew T G Holden, Simon Heilbronner
"Gene accordions" cause genotypic and phenotypic heterogeneity in clonal populations of Staphylococcus aureus.
Nat Commun: 2020, 11(1);3526
[PubMed:32665571] [WorldCat.org] [DOI] (I e)Christina Schluepen, Enrico Malito, Ambra Marongiu, Markus Schirle, Elisabeth McWhinnie, Paola Lo Surdo, Marco Biancucci, Fabiana Falugi, Vincenzo Nardi-Dei, Sara Marchi, Maria Rita Fontana, Benedetta Lombardi, Maria Grazia De Falco, C Daniela Rinaudo, Glen Spraggon, Mikkel Nissum, Fabio Bagnoli, Guido Grandi, Matthew J Bottomley, Sabrina Liberatori
Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus.
Biochem J: 2013, 455(3);273-84
[PubMed:23895222] [WorldCat.org] [DOI] (I p)Jeffrey S Kavanaugh, Caralyn E Flack, Jessica Lister, Erica B Ricker, Carolyn B Ibberson, Christian Jenul, Derek E Moormeier, Elizabeth A Delmain, Kenneth W Bayles, Alexander R Horswill
Identification of Extracellular DNA-Binding Proteins in the Biofilm Matrix.
mBio: 2019, 10(3);
[PubMed:31239382] [WorldCat.org] [DOI] (I e)