⊟Summary[edit | edit source]

pan ID^?: SAUPAN000902000
symbol^?: —
synonym:
description^?: oleate hydratase
- oleate hydratase
- myosin-cross-reactive antigen
- 67 kDa Myosin-crossreactive antigen
- 67 kDa myosin-cross-reactive antigen like family protein
- 67 kDa Myosin-crossreactive antigen-like protein
- 67 kDa Myosin-crossreactive streptococcal antigen
- antigen, 67 kDa
- putative myosin-crossreactive antigen
strand^?: -
coordinates^?: 1166681..1168456
synteny block^?: BlockID0004400
occurrence^?: in 100% of 33 strains

ohyA (rok): antimicrobial fatty acid resistance hydratase ^[1]

⊟Orthologs[edit | edit source]

COL:

N315:

NCTC8325:

Newman:

USA300_FPR3757:

04-02981:

SA2981_0106

08BA02176:

C248_0095

11819-97:

MS7_0100

6850:

RSAU_000062

71193:

ST398NM01_0119

ECT-R 2:

ECTR2_62

ED133:

SAOV_0055

ED98:

SAAV_0073

HO 5096 0412:

SAEMRSA15_00740

JH1:

SaurJH1_0097

JH9:

SaurJH9_0093

JKD6008:

SAA6008_00086

JKD6159:

SAA6159_00091

LGA251:

SARLGA251_00810

M013:

M013TW_0095

MRSA252:

SAR0111

MSHR1132:

SAMSHR1132_00810

MSSA476:

SAS0082

Mu3:

SAHV_0105

Mu50:

SAV0106

MW2:

MW0081

RF122:

SAB0045c

ST398:

SAPIG0119

T0131:

SAT0131_00090

TCH60:

HMPREF0772_10389

TW20:

SATW20_01200

USA300_TCH1516:

USA300HOU_0117

VC40:

SAVC_00270

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]

alignment of orthologues:
CLUSTAL format alignment by MAFFT L-INS-i (v7.307)

COL             MYYSYGNYEAFARPKKPENVENKSAYLIGSGLASLAAACFLIRDGQMEGSKIHILEELPK
N315            MYYSYGNYEAFARPKKPENVENKSAYLIGSGLASLAAACFLIRDGQMEGSKIHILEELPK
NCTC8325        MYYSYGNYEAFARPKKPENVENKSAYLIGSGLASLAAACFLIRDGQMEGSKIHILEELPK
Newman          MYYSYGNYEAFARPKKPENVENKSAYLIGSGLASLAAACFLIRDGQMEGSKIHILEELPK
USA300_FPR3757  MYYSYGNYEAFARPKKPENVENKSAYLIGSGLASLAAACFLIRDGQMEGSKIHILEELPK
                ************************************************************

COL             AGGSLDGENMPLKGYVVRGGREMENHFECLWDLFRSIPSLEIDNASVLDEFYWLNKEDPN
N315            AGGSLDGENMPLKGYVVRGGREMENHFECLWDLFRSIPSLEIDNASVLDEFYWLNKEDPN
NCTC8325        AGGSLDGENMPLKGYVVRGGREMENHFECLWDLFRSIPSLEIDNASVLDEFYWLNKEDPN
Newman          AGGSLDGENMPLKGYVVRGGREMENHFECLWDLFRSIPSLEIDNASVLDEFYWLNKEDPN
USA300_FPR3757  AGGSLDGENMPLKGYVVRGGREMENHFECLWDLFRSIPSLEIDNASVLDEFYWLNKEDPN
                ************************************************************

COL             YSRCRVIEKQGQRLVTDGDFTLTKTAIKEILDLCLTNEEDLDDVKITDVFSDDFFNSNFW
N315            YSRCRVIEKQGQRLVTDGDFTLTKTAIKEILDLCLTNEEDLDDVKITDVFSDDFFNSNFW
NCTC8325        YSRCRVIEKQGQRLVTDGDFTLTKTAIKEILDLCLTNEEDLDDVKITDVFSDDFFNSNFW
Newman          YSRCRVIEKQGQRLVTDGDFTLTKTAIKEILDLCLTNEEDLDDVKITDVFSDDFFNSNFW
USA300_FPR3757  YSRCRVIEKQGQRLVTDGDFTLTKTAIKEILDLCLTNEEDLDDVKITDVFSDDFFNSNFW
                ************************************************************

COL             IYWKTMFAFEPWHSAMEMRRYLMRFVHHISGLADFSALKFTKYNQYESLVLPMVEYLKSH
N315            IYWKTMFAFEPWHSAMEMRRYLMRFVHHIGGLADFSALKFTKYNQYESLVLPMVEYLKSH
NCTC8325        IYWKTMFAFEPWHSAMEMRRYLMRFVHHISGLADFSALKFTKYNQYESLVLPMVEYLKSH
Newman          IYWKTMFAFEPWHSAMEMRRYLMRFVHHISGLADFSALKFTKYNQYESLVLPMVEYLKSH
USA300_FPR3757  IYWKTMFAFEPWHSAMEMRRYLMRFVHHISGLADFSALKFTKYNQYESLVLPMVEYLKSH
                *****************************.******************************

COL             GVQFEYDVKVEDIKIDVTTSQKIAREILIDRNGNAESIKLTINDLVFVTNGSITESSTYG
N315            GVQFEYDVKVEDIKVDVTTSQKIAREILIHRHGKAESIKLTVDDLVFVTNGSITESSTYG
NCTC8325        GVQFEYDVKVEDIKIDVTTSQKIAREILIDRNGNAESIKLTINDLVFVTNGSITESSTYG
Newman          GVQFEYDVKVEDIKIDVTTSQKIAREILIDRNGNAESIKLTINDLVFVTNGSITESSTYG
USA300_FPR3757  GVQFEYDVKVEDIKIDVTTSQKIAREILIDRNGNAESIKLTINDLVFVTNGSITESSTYG
                **************:**************.*:*:*******::*****************

COL             DNDTPAPPTDELGGSWTLWKNLARQSPEFGNPDKFCQNIPKKSWFVSATSTTNNKEIIDT
N315            DNDTPAPPTDELGGSWTLWKNLARQSPEFGNPDKFCQNIPKKSWFVSATSTTNNKEIIDT
NCTC8325        DNDTPAPPTDELGGSWTLWKNLARQSPEFGNPDKFCQNIPKKSWFVSATSTTNNKEIIDT
Newman          DNDTPAPPTDELGGSWTLWKNLARQSPEFGNPDKFCQNIPKKSWFVSATSTTNNKEIIDT
USA300_FPR3757  DNDTPAPPTDELGGSWTLWKNLARQSPEFGNPDKFCQNIPKKSWFVSATSTTNNKEIIDT
                ************************************************************

COL             IESICKRDPLAGKTVTGGIITINDSAWQMSFTINRQQQFKDQPENEISTWIYALYSDVNG
N315            IESICKRDPLAGKTVTGGIITINDSAWQMSFTINRQQQFKDQPENEISTWIYALYSDVNG
NCTC8325        IESICKRDPLAGKTVTGGIITINDSAWQMSFTINRQQQFKDQPENEISTWIYALYSDVNG
Newman          IESICKRDPLAGKTVTGGIITINDSAWQMSFTINRQQQFKDQPENEISTWIYALYSDVNG
USA300_FPR3757  IESICKRDPLAGKTVTGGIITINDSAWQMSFTINRQQQFKDQPENEISTWIYALYSDVNG
                ************************************************************

COL             DYIKKPITECSGNEICQEWLYHLGVSTDKIEDLAKHASNTIPVYMPYITSYFMTRAIGDR
N315            DYIKKPITECSGNEICQEWLYHLGVSTDKIEDLAKHVSNTIPVYMPYITSYFMTRAIGDR
NCTC8325        DYIKKPITECSGNEICQEWLYHLGVSTDKIEDLAKHASNTIPVYMPYITSYFMTRAIGDR
Newman          DYIKKPITECSGNEICQEWLYHLGVSTDKIEDLAKHASNTIPVYMPYITSYFMTRAIGDR
USA300_FPR3757  DYIKKPITECSGNEICQEWLYHLGVSTDKIEDLAKHASNTIPVYMPYITSYFMTRAIGDR
                ************************************.***********************

COL             PLVVPHQSQNLAFIGNFAETERDTVFTTEYSVRTAMEAVYQLLNIDRGIPEVINSPFDLR
N315            PLVVPHQSQNLSFIGNFAETERDTVFTTEYSVRTAMEAVYQLLNIDRGIPEVINSTFDLR
NCTC8325        PLVVPHQSQNLAFIGNFAETERDTVFTTEYSVRTAMEAVYQLLNIDRGIPEVINSPFDLR
Newman          PLVVPHQSQNLAFIGNFAETERDTVFTTEYSVRTAMEAVYQLLNIDRGIPEVINSPFDLR
USA300_FPR3757  PLVVPHQSQNLAFIGNFAETERDTVFTTEYSVRTAMEAVYQLLNIDRGIPEVINSPFDLR
                ***********:*******************************************.****

COL             VLMDAIYELNDHQDLREITKDSKMQKLALAGFLKKIKGTYIESLLKEHKLL
N315            VLMDAVYELNDHQDLREITKDSKMQKLALAGFLKKIKGTYIETLLKEHKLL
NCTC8325        VLMDAIYELNDHQDLREITKDSKMQKLALAGFLKKIKGTYIESLLKEHKLL
Newman          VLMDAIYELNDHQDLREITKDSKMQKLALAGFLKKIKGTYIESLLKEHKLL
USA300_FPR3757  VLMDAIYELNDHQDLREITKDSKMQKLALAGFLKKIKGTYIESLLKEHKLL
                *****:************************************:********

↑ Chitra Subramanian, Matthew W Frank, Justin L Batte, Sarah G Whaley, Charles O Rock
Oleate hydratase from Staphylococcus aureus protects against palmitoleic acid, the major antimicrobial fatty acid produced by mammalian skin.
J Biol Chem: 2019, 294(23);9285-9294
[PubMed:31018965] [WorldCat.org] [DOI] (I p)Natalia Malachowa, Petra L Kohler, Patrick M Schlievert, Olivia N Chuang, Gary M Dunny, Scott D Kobayashi, Jacek Miedzobrodzki, Gregory A Bohach, Keun Seok Seo
Characterization of a Staphylococcus aureus surface virulence factor that promotes resistance to oxidative killing and infectious endocarditis.
Infect Immun: 2011, 79(1);342-52
[PubMed:20937760] [WorldCat.org] [DOI] (I p)

[1] Chitra Subramanian, Matthew W Frank, Justin L Batte, Sarah G Whaley, Charles O Rock
Oleate hydratase from Staphylococcus aureus protects against palmitoleic acid, the major antimicrobial fatty acid produced by mammalian skin.
J Biol Chem: 2019, 294(23);9285-9294
[PubMed:31018965] [WorldCat.org] [DOI] (I p)Natalia Malachowa, Petra L Kohler, Patrick M Schlievert, Olivia N Chuang, Gary M Dunny, Scott D Kobayashi, Jacek Miedzobrodzki, Gregory A Bohach, Keun Seok Seo
Characterization of a Staphylococcus aureus surface virulence factor that promotes resistance to oxidative killing and infectious endocarditis.
Infect Immun: 2011, 79(1);342-52
[PubMed:20937760] [WorldCat.org] [DOI] (I p)

[1]

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Contents

⊟Summary[edit | edit source]

⊟Orthologs[edit | edit source]

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

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⊟Summary[edit | edit source]

⊟Orthologs[edit | edit source]

⊟Genome Viewer[edit | edit source]

⊟Alignments[edit | edit source]