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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40
⊟Summary[edit | edit source]
- pan ID?: SAUPAN001498000
- symbol?: —
- synonym:
- description?: phage protein
- strand?: -
- coordinates?: 1750797..1751117
- synteny block?: BlockID0009730
- occurrence?: in 18% of 34 strains
hypothetical phi69 ORF45-like DUF771 phage protein [1]
Although originally suspected to be the toxin component of a toxin-antitoxin system, the proposed antitoxin component is actually the MurG inhibitor toxin Gp11. This leaves the functional role of this HigB homologue unclear.
⊟Orthologs[edit | edit source]
COL:
—
N315:
—
NCTC8325:
—
04-02981:
—
08BA02176:
—
11819-97:
—
6850:
—
71193:
—
ECT-R 2:
—
ED133:
—
ED98:
SAAV_2056
HO 5096 0412:
—
JH1:
—
JH9:
—
JKD6008:
—
JKD6159:
SAA6159_01924
JSNZ:
—
LGA251:
—
M013:
—
MRSA252:
—
MSHR1132:
SAMSHR1132_18340
MSSA476:
—
Mu3:
—
Mu50:
—
MW2:
—
RF122:
—
ST398:
—
T0131:
—
TCH60:
—
TW20:
—
USA300_TCH1516:
USA300HOU_1997
VC40:
—
⊟Genome Viewer[edit | edit source]
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
Newman MPHILNVTVPIPETHVLITKDEYDELIGYSLDPVWNMSDLKKKLKIASDETIKDRLLFHP
USA300_FPR3757 MPHILNVTVPIPETHVLITKDEYDELIGYSLDPVWNMSDLKKKLKIASDETIKDRLLFHP
************************************************************
Newman RFEKELRAQGIVHYPDENFNRWRFNARKMNKFVDEHFNEIYKERIK
USA300_FPR3757 RFEKELRAQGIVHYPDESFNRWRFNARKMNKFVDEHFNEIYKERIK
*****************.****************************
- ↑ Gul Habib, Qing Zhu, Baolin Sun
Bioinformatics and Functional Assessment of Toxin-Antitoxin Systems in Staphylococcus aureus.
Toxins (Basel): 2018, 10(11);
[PubMed:30441856] [WorldCat.org] [DOI] (I e)Qi Xu, Li Tang, Weilin Liu, Neng Xu, Yangbo Hu, Yong Zhang, Shiyun Chen
Phage protein Gp11 blocks Staphylococcus aureus cell division by inhibiting peptidoglycan biosynthesis.
mBio: 2024, 15(6);e0067924
[PubMed:38752726] [WorldCat.org] [DOI] (I p)