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⊟Summary[edit | edit source]
- pan ID?: SAUPAN001836000
- symbol?: —
- synonym:
- description?: HNH endonuclease
- HNH endonuclease
- bacteriophage L54a HNH endonuclease family protein
- phiSLT ORF 104b-like protein
- prophage L54a, HNH endonuclease
- bacteriophage L54a, HNH endonuclease family protein
- HNH endonuclease family protein
- phage endonuclease
- phage protein
- prophage L54a
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 2286736..2287056
- synteny block?: BlockID0012120
- occurrence?: in 41% of 34 strains
hnh : serogroup A prophage terminase-associated HNH endonuclease [1]
Prophage terminase-associated endonucleases mediate concatenated genome separation during phage head filling for cos site-type prophage. This version specifically associates with TerL of Serogroup A prophages.
⊟Orthologs[edit | edit source]
04-02981:
—
08BA02176:
C248_0347
11819-97:
MS7_1470
6850:
—
71193:
—
ECT-R 2:
—
ED133:
—
ED98:
SAAV_2034
HO 5096 0412:
SAEMRSA15_13760
JH1:
SaurJH1_1077
JH9:
SaurJH9_1057
JKD6008:
—
JKD6159:
—
JSNZ:
—
LGA251:
—
M013:
—
MRSA252:
SAR1521
MSHR1132:
—
MSSA476:
SAS0930
Mu3:
—
Mu50:
—
MW2:
MW1403
RF122:
—
ST398:
SAPIG0371
T0131:
—
TCH60:
HMPREF0772_11688
TW20:
—
USA300_TCH1516:
—
VC40:
—
⊟Genome Viewer[edit | edit source]
| COL | |
| NCTC8325 | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MTKHNNIYKHGRKSYQYDWFYHSKAWKKLREIALDRDNYLCQMCLREDIITDAKIVHHII
NCTC8325 MTKHNNIYKHGRKSYQYDWFYHSKAWKKLREIALDRDNHLCQMCLREDIVTDANIVHHII
USA300_FPR3757 MTKHNNIYKHGRKSYQYDWFYHSKAWKKLREIALDRDNHLCQMCLREDIVTDANIVHHII
**************************************:**********:***:******
COL YVDEDFNKALDLDNLMSVCYSCHNKIHANDNDKSNLKKIRVLKI
NCTC8325 YVDEDFNKALDLDNLMSVCYSCHNKIHANDNDKSNLKKIRVLKI
USA300_FPR3757 YVDEDFNKALELDNLMSVCYGCHNKIHANGNDKSNLKKIRVLKI
**********:*********.********.**************
- ↑ Nuria Quiles-Puchalt, Nuria Carpena, Juan C Alonso, Richard P Novick, Alberto Marina, José R Penadés
Staphylococcal pathogenicity island DNA packaging system involving cos-site packaging and phage-encoded HNH endonucleases.
Proc Natl Acad Sci U S A: 2014, 111(16);6016-21
[PubMed:24711396] [WorldCat.org] [DOI] (I p)Smriti Kala, Nichole Cumby, Paul D Sadowski, Batool Zafar Hyder, Voula Kanelis, Alan R Davidson, Karen L Maxwell
HNH proteins are a widespread component of phage DNA packaging machines.
Proc Natl Acad Sci U S A: 2014, 111(16);6022-7
[PubMed:24711378] [WorldCat.org] [DOI] (I p)Michael Feiss, Venigalla B Rao
The bacteriophage DNA packaging machine.
Adv Exp Med Biol: 2012, 726;489-509
[PubMed:22297528] [WorldCat.org] [DOI] (P p)