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⊟Summary[edit | edit source]
- pan ID?: SAUPAN002164000
- symbol?: mpsB
- synonym:
- description?: hypothetical protein with DUF2309
- hypothetical protein with DUF2309
- YbcC family protein
- putative transmembrane protein coupled to NADH-ubiquinone oxidoreductase chain 5
- transmembrane protein coupled to NADH-ubiquinone oxidoreductase chain 5
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 2669474..2672195
- synteny block?: BlockID0014650
- occurrence?: in 100% of 33 strains
mpsB : membrane potential-generating system activity modulation protein [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0429
08BA02176:
C248_0503
11819-97:
MS7_0426
6850:
RSAU_000386
71193:
ST398NM01_0519
ECT-R 2:
ECTR2_387
ED133:
SAOV_0470
ED98:
SAAV_0396
HO 5096 0412:
SAEMRSA15_03780
JH1:
SaurJH1_0488
JH9:
SaurJH9_0475
JKD6008:
SAA6008_00456
JKD6159:
SAA6159_00404
LGA251:
SARLGA251_03870
M013:
M013TW_0417
MRSA252:
SAR0453
MSHR1132:
SAMSHR1132_03980
MSSA476:
SAS0411
Mu3:
SAHV_0451
Mu50:
SAV0453
MW2:
MW0408
RF122:
SAB0403
ST398:
SAPIG0519
T0131:
SAT0131_00491
TCH60:
HMPREF0772_10069
TW20:
SATW20_05220
USA300_TCH1516:
USA300HOU_0458
VC40:
SAVC_01855
⊟Genome Viewer[edit | edit source]
COL | |
N315 | |
NCTC8325 | |
Newman | |
USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNK
N315 MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNK
NCTC8325 MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNK
Newman MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNK
USA300_FPR3757 MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNK
************************************************************
COL ALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYIDNIKTLKDVPASYMNHSNV
N315 ALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYIDNIKTLKDVPASYMNHSNV
NCTC8325 ALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYIDNIKTLKDVPASYMNHSNV
Newman ALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYIDNIKTLKDVPASYMNHSNV
USA300_FPR3757 ALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYIDNIKTLKDVPASYMNHSNV
************************************************************
COL DVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLS
N315 DVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLS
NCTC8325 DVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLS
Newman DVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLS
USA300_FPR3757 DVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLS
************************************************************
COL SWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTHFSIDQEDYQA
N315 SWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTYFSIDQEDYQA
NCTC8325 SWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTHFSIDQEDYQA
Newman SWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTHFSIDQEDYQA
USA300_FPR3757 SWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTHFSIDQEDYQA
*************************************************:**********
COL YVEGHLLALPGWAGMLYYRSQQHHFEQHLLTDYLAIRLVVEQLLVGDEFKSVAKDCESRS
N315 YVEGHLLALPGWAGMLYYRSQQHHFEQHLLTDYLAIRLVVEQLLVGDEFKSVTKDCESRS
NCTC8325 YVEGHLLALPGWAGMLYYRSQQHHFEQHLLTDYLAIRLVVEQLLVGDEFKSVAKDCESRS
Newman YVEGHLLALPGWAGMLYYRSQQHHFEQHLLTDYLAIRLVVEQLLVGDEFKSVAKDCESRS
USA300_FPR3757 YVEGHLLALPGWAGMLYYRSQQHYFEQHLLTDYLAIRLVVEQLLVGDEFKSVAKDCESRS
***********************:****************************:*******
COL ENWFKQTVASWCYYSDMPSDVLLQHDVNEIQTFIHFAATMNKNVFKNLWLIAWEMTYESQ
N315 ENWFKQTVASLCYYSDMPSDVLLQHDVNEIQTFIHFAATMNKNVFKNLWLIAWEMTYESQ
NCTC8325 ENWFKQTVASWCYYSDMPSDVLLQHDVNEIQTFIHFAATMNKNVFKNLWLIAWEMTYESQ
Newman ENWFKQTVASWCYYSDMPSDVLLQHDVNEIQTFIHFAATMNKNVFKNLWLIAWEMTYESQ
USA300_FPR3757 ENWFKQTVASWCYYSDMPSDVLLQHDVNEIQTFIHFAATMNKNVFKNLWLIAWEMTYESQ
********** *************************************************
COL LKQKIKAGHESVAGALDVNQVNVSENDNANQPHSVLLNDTQAVDENNSELNQMGTSTKAQ
N315 LKQKIKAGHESVAGALDVNQVNVSENDNANQPHSVLLNDTQAVDENNSELNQVGTSTKAQ
NCTC8325 LKQKIKAGHESVAGALDVNQVNVSENDNANQPHSVLLNDTQAVDENNSELNQMGTSTKAQ
Newman LKQKIKAGHESVAGALDVNQVNVSENDNANQPHSVLLNDTQAVDENNSELNQMGTSTKAQ
USA300_FPR3757 LKQKIKAGHESVAGALDVNQVNVSENDNANQPHSVLLNDTQAVDENNSELNQMGTSTKAQ
****************************************************:*******
COL IAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIK
N315 IAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIK
NCTC8325 IAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIK
Newman IAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIK
USA300_FPR3757 IAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIK
************************************************************
COL EFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKS
N315 EFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKS
NCTC8325 EFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKS
Newman EFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKS
USA300_FPR3757 EFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKS
************************************************************
COL RASLQKIKQKWLKKPETKLTIDREFDRTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPF
N315 RASLQKIKQKWLKKPETKLTIDREFDRTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPF
NCTC8325 RASLQKIKQKWLKKPETKLTIDREFDRTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPF
Newman RASLQKIKQKWLKKPETKLTIDREFDRTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPF
USA300_FPR3757 RASLQKIKQKWLKKPETKLTIDREFDRTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPF
************************************************************
COL VVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETT
N315 VVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETT
NCTC8325 VVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETT
Newman VVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETT
USA300_FPR3757 VVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETT
************************************************************
COL VFAVAEHHTSTDTLAWVYVPDTLSSIALDAYESLNDAMPMISEHANRERLDKLPTIGRVN
N315 VFAAAEHHTSTDTLAWVYVPDTLSALALDAYESLNDAMPMISEQANRERLDKLPTIGRVN
NCTC8325 VFAVAEHHTSTDTLAWVYVPDTLSSIALDAYESLNDAMPMISEHANRERLDKLPTIGRVN
Newman VFAVAEHHTSTDTLAWVYVPDTLSSIALDAYESLNDAMPMISEHANRERLDKLPTIGRVN
USA300_FPR3757 VFAVAEHHTSTDTLAWVYVPDTLSSIALDAYESLNDAMPMISEHANRERLDKLPTIGRVN
***.********************::*****************:****************
COL HPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGTL
N315 HPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGKL
NCTC8325 HPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGTL
Newman HPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGTL
USA300_FPR3757 HPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGTL
**********************************************************.*
COL LNTIISGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQ
N315 LNTIISGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQ
NCTC8325 LNTIISGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQ
Newman LNTIISGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQ
USA300_FPR3757 LNTIISGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQ
************************************************************
COL SVMAADRTMYHSPIRLLVVIQAPDYVVARLLANNEHFARKVSNHWLRLMSVNEEGRFKSW
N315 SVMAADRTMYHSPIRLLVVIQAPDYVVARLFANNEHFARKVSNHWLRLMSVNEEGRFKSW
NCTC8325 SVMAADRTMYHSPIRLLVVIQAPDYVVARLLANNEHFARKVSNHWLRLMSVNEEGRFKSW
Newman SVMAADRTMYHSPIRLLVVIQAPDYVVARLLANNEHFARKVSNHWLRLMSVNEEGRFKSW
USA300_FPR3757 SVMAADRTMYHSPIRLLVVIQAPDYVVARLLANNEHFARKVSNHWLRLMSVNEEGRFKSW
******************************:*****************************
COL I
N315 I
NCTC8325 I
Newman I
USA300_FPR3757 I
*
- ↑ Sonja Mayer, Wojtek Steffen, Julia Steuber, Friedrich Götz
The Staphylococcus aureus NuoL-like protein MpsA contributes to the generation of membrane potential.
J Bacteriol: 2015, 197(5);794-806
[PubMed:25448817] [WorldCat.org] [DOI] (I p)Edward J A Douglas, Seána Duggan, Tarcisio Brignoli, Ruth C Massey
The MpsB protein contributes to both the toxicity and immune evasion capacity of Staphylococcus aureus.
Microbiology (Reading): 2021, 167(10);
[PubMed:34618666] [WorldCat.org] [DOI] (I p)Sook-Ha Fan, Richard A Proctor, Selvi C Ersoy, Adhar C Manna, Ambrose L Cheung, Friedrich Götz, Henry F Chambers, Arnold S Bayer
Role of the NaHCO 3 Transporter MpsABC in the NaHCO 3-β-Lactam-Responsive Phenotype in Methicillin-Resistant Staphylococcus aureus.
Microbiol Spectr: 2023, 11(3);e0014123
[PubMed:37102972] [WorldCat.org] [DOI] (I p)