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⊟Summary[edit | edit source]
- pan ID?: SAUPAN002513000
- symbol?: tagH
- synonym: tarH
- description?: teichoic acids export protein ATP-binding subunit
- teichoic acids export protein ATP-binding subunit
- teichoic acids export ATP-binding protein TagH
- teichoic acids export ABC transporter ATP-binding subunit TagH
- teichoic acid ABC transporter ATP-binding protein, putative
- teichoic acid ABC transporter ATP-bindingprotein
- O-antigen export system ATP-binding protein rfbB
- teichoic acid ABC transporter protein, putative
- Teichoic acid export ATP-binding protein, TagH
- Teichoic acid export ATP-binding protein TagH
- teichoic acids ABC superfamily ATP binding cassette transporter, ABC protein
- teichoic acids export ATP-binding protein TagH (Teichoicacid-transporting ATPase)
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 3025859..3026653
- synteny block?: BlockID0017490
- occurrence?: in 100% of 34 strains
tarH (tagH) : teichoic acid export ATP-binding subunit [1]
Wall teichoic acids in S. aureus use ribitol exclusively as their polyol monomer; therefore teichoic acid enzymes in S. aureus are assigned the "tar" nomenclature. In contrast, S. epidermidis uses glycerol as its polyol monomer so orthologous enzymes in S. epidermidis are assigned the "tag" nomenclature. TarGH assembles as a dimer of heterodimers to pass polymerized, undecaprenol-linked wall teichoic acid components to the outer leaflet of the cell membrane.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0613 (tagH)
08BA02176:
C248_0719 (tagH)
11819-97:
MS7_0688 (tagH)
6850:
RSAU_000593 (tagH)
71193:
ST398NM01_0716
ECT-R 2:
ECTR2_589
ED133:
SAOV_0672c
ED98:
SAAV_0600
HO 5096 0412:
SAEMRSA15_05630 (tagH)
JH1:
SaurJH1_0675
JH9:
SaurJH9_0660
JKD6008:
SAA6008_00654 (tagH)
JKD6159:
SAA6159_00592 (tagH)
LGA251:
SARLGA251_05710 (tagH)
M013:
M013TW_0625
MRSA252:
SAR0647 (tagH)
MSHR1132:
SAMSHR1132_05830
MSSA476:
SAS0603
Mu3:
SAHV_0634 (tagH)
Mu50:
SAV0637 (tagH)
MW2:
MW0599 (tagH)
RF122:
SAB0587c (tagH)
ST398:
SAPIG0716
T0131:
SAT0131_00706 (pfl)
TCH60:
HMPREF0772_12550 (rfbB)
TW20:
SATW20_07120 (tagH)
USA300_TCH1516:
USA300HOU_0657 (tagH)
VC40:
SAVC_02820
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 | |
| JSNZ |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.505)
COL MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGING
N315 MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGING
NCTC8325 MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGING
Newman MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGING
USA300_FPR3757 MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGING
JSNZ MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGING
************************************************************
COL SGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEI
N315 SGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEI
NCTC8325 SGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEI
Newman SGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEI
USA300_FPR3757 SGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEI
JSNZ SGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEI
************************************************************
COL KAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQ
N315 KAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQ
NCTC8325 KAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQ
Newman KAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQ
USA300_FPR3757 KAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQ
JSNZ KAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQ
************************************************************
COL KCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLND
N315 KCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLND
NCTC8325 KCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLND
Newman KCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLND
USA300_FPR3757 KCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLND
JSNZ KCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLND
************************************************************
COL FKKKSKAEQKEFRNKLDESRFVIK
N315 FKKKSKAEQKEFRNKLDEARFVIK
NCTC8325 FKKKSKAEQKEFRNKLDESRFVIK
Newman FKKKSKAEQKEFRNKLDESRFVIK
USA300_FPR3757 FKKKSKAEQKEFRNKLDESRFVIK
JSNZ FKKKSKAEQKEFRNKLDESRFVIK
******************:*****
- ↑ Kiran B Tiwari, Craig Gatto, Suzanne Walker, Brian J Wilkinson
Exposure of Staphylococcus aureus to Targocil Blocks Translocation of the Major Autolysin Atl across the Membrane, Resulting in a Significant Decrease in Autolysis.
Antimicrob Agents Chemother: 2018, 62(7);
[PubMed:29735561] [WorldCat.org] [DOI] (I e)