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⊟Summary[edit | edit source]
- pan ID?: SAUPAN003127000
- symbol?: fabH
- synonym:
- description?: 3-oxoacyl-ACP synthase III
- 3-oxoacyl-ACP synthase III
- 3-oxoacyl-(acyl carrier protein) synthase III
- 3-oxoacyl-ACP synthase
- ketoacyl-ACP synthase III
- 3-oxoacyl--(acyl carrier protein) synthase II
- 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII
- 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1 (3-oxoacyl-[acyl-carrier-protein] synthase III protein 1) (Beta-ketoacyl-ACP synthase III 1) (KAS III 1) (bFabH1)
- 3-oxoacyl- synthase ,KASIII
- 3-oxoacyl synthase III
- putative 3-oxoacyl-[acyl-carrier-protein]synthase III
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 3510158..3511099
- synteny block?: BlockID0022190
- occurrence?: in 100% of 33 strains
fabH: beta-ketoacyl-(acyl-carrier-protein) synthase III [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_0938
08BA02176:
C248_1006 (fabH)
11819-97:
MS7_0938 (fabH)
6850:
RSAU_000858 (fabH)
71193:
ST398NM01_0979
ECT-R 2:
ECTR2_838 (fabH)
ED133:
SAOV_0929
ED98:
SAAV_0944 (fabH)
HO 5096 0412:
SAEMRSA15_08120 (fabH)
JH1:
SaurJH1_1001
JH9:
SaurJH9_0982
JKD6008:
SAA6008_00936 (fabH)
JKD6159:
SAA6159_00839 (fabH)
LGA251:
SARLGA251_09000 (fabH)
M013:
M013TW_0905
MRSA252:
SAR0946 (fabH)
MSHR1132:
SAMSHR1132_08310
MSSA476:
SAS0853
Mu3:
SAHV_0978 (fabH)
Mu50:
SAV0983 (fabH)
MW2:
MW0865 (fabH)
RF122:
SAB0848 (fabH)
ST398:
SAPIG0979
T0131:
SAT0131_01016 (atpE)
TCH60:
HMPREF0772_12262 (fabH)
TW20:
SATW20_09820 (fabH)
USA300_TCH1516:
USA300HOU_0941 (fabH1)
VC40:
SAVC_04085
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASL
N315 MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASV
NCTC8325 MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASL
Newman MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASL
USA300_FPR3757 MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASL
***********************************************************:
COL KAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMI
N315 KAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMI
NCTC8325 KAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMI
Newman KAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMI
USA300_FPR3757 KAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMI
************************************************************
COL TAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSDGRGIISYEM
N315 TAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSEGRGIISYEM
NCTC8325 TAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSDGRGIISYEM
Newman TAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSDGRGIISYEM
USA300_FPR3757 TAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSDGRGIISYEM
**************************************************:*********
COL GSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQA
N315 GSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQA
NCTC8325 GSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQA
Newman GSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQA
USA300_FPR3757 GSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQA
************************************************************
COL NIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKIKDDDTIVLVGFGG
N315 NIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKLKDDDTIVLVGFGG
NCTC8325 NIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKIKDDDTIVLVGFGG
Newman NIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKIKDDDTIVLVGFGG
USA300_FPR3757 NIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKIKDDDTIVLVGFGG
**********************************************:*************
COL GLTWGAMTIKWGK
N315 GLTWGAMTIKWGK
NCTC8325 GLTWGAMTIKWGK
Newman GLTWGAMTIKWGK
USA300_FPR3757 GLTWGAMTIKWGK
*************
- ↑ Xin He, Kevin A Reynolds
Purification, characterization, and identification of novel inhibitors of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureus.
Antimicrob Agents Chemother: 2002, 46(5);1310-8
[PubMed:11959561] [WorldCat.org] [DOI] (P p)