PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN003359000
• symbol^?: isdA
• synonym:
• description^?: iron-regulated surface determinant protein A

  descriptions from strain specific annotations:

  • iron-regulated surface determinant protein A
  • cell surface protein
  • heme-iron transport protein IsdA
  • iron-regulated heme-iron binding protein IsdA
  • iron transport associated domain-containing protein
  • LPXTG-anchored heme-scavenging protein IsdA
  • LPXTG cell wall surface anchor protein
  • cell surface protein IsdA
  • Cell surface protein IsdA, transfers heme from hemoglobin to apo-IsdC
  • cell surface transferrin-binding protein
  • cell wall anchor domain-containing protein
  • iron (Fe2+)-regulated surface determinant protein IsdA
  • iron-regulated heme-iron binding protein
  • iron-regulated surface determinant protein A (Staphylococcaltransferrin-binding protein A) (Fur-regulated protein A)
  • LPXTG-motif cell wall anchor domain-containing protein
• strand^?: -
• coordinates^?: 3725253..3727066
• synteny block^?: BlockID0024420
• occurrence^?: in 100% of 33 strains

⊟Orthologs

COL:
SACOL1140 (isdA)
N315:
SA0977 (isdA)
NCTC8325:
SAOUHSC_01081
Newman:
NWMN_1041 (isdA)
USA300_FPR3757:
SAUSA300_1029
04-02981:
SA2981_1086 (isdA)
08BA02176:
C248_1156 (isdA)
11819-97:
MS7_1086 (isdA)
6850:
RSAU_001014 (isdA)
71193:
ST398NM01_1126
ECT-R 2:
ECTR2_984
ED133:
SAOV_1126c (isdB)
ED98:
SAAV_1096 (isdA)
HO 5096 0412:
SAEMRSA15_09590 (isdA)
JH1:
SaurJH1_1211
JH9:
SaurJH9_1189
JKD6008:
SAA6008_01084 (isdA)
JKD6159:
SAA6159_00984 (isdA)
LGA251:
SARLGA251_10420 (isdA)
M013:
M013TW_1061
MRSA252:
SAR1103 (isdA)
MSHR1132:
SAMSHR1132_09760
MSSA476:
SAS1064
Mu3:
SAHV_1121
Mu50:
SAV1130
MW2:
MW1012 (isdA)
RF122:
SAB0994c (isdB)
ST398:
SAPIG1126
T0131:
SAT0131_01169
TCH60:
HMPREF0772_12103 (isdA)
TW20:
SATW20_11240 (isdA)
USA300_TCH1516:
USA300HOU_1064 (isdA)
VC40:
SAVC_04810

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNAPNNQSTQ
  N315            MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNATNNQSTQ
  NCTC8325        MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNATNNQSTQ
  Newman          MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNATNNQSTQ
  USA300_FPR3757  MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNATNNQSTQ
                  *****************************************************.******
  
  COL             VSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYN
  N315            VSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYN
  NCTC8325        VSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYN
  Newman          VSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYN
  USA300_FPR3757  VSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYN
                  ************************************************************
  
  COL             ANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAI
  N315            ANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAI
  NCTC8325        ANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAI
  Newman          ANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAI
  USA300_FPR3757  ANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAI
                  ************************************************************
  
  COL             PTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVST
  N315            PTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVST
  NCTC8325        PTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVST
  Newman          PTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVST
  USA300_FPR3757  PTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVST
                  ************************************************************
  
  COL             DTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKH
  N315            DTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKH
  NCTC8325        DTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKH
  Newman          DTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKH
  USA300_FPR3757  DTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKH
                  ************************************************************
  
  COL             NETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
  N315            NETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
  NCTC8325        NETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
  Newman          NETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
  USA300_FPR3757  NETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
                  **************************************************