PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN003453000
• symbol^?: murD
• synonym:
• description^?: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase

  descriptions from strain specific annotations:

  • UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase
  • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
  • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase MurD
  • UDP-N-acetylmuramoylalanine--D-glutamate ligase
• strand^?: +
• coordinates^?: 3797286..3798650
• synteny block^?: BlockID0025330
• occurrence^?: in 100% of 33 strains

⊟Orthologs

COL:
SACOL1196 (murD)
N315:
SA1026 (murD)
NCTC8325:
SAOUHSC_01147 (murD)
Newman:
NWMN_1093 (murD)
USA300_FPR3757:
SAUSA300_1077 (murD)
04-02981:
SA2981_1141 (murD)
08BA02176:
C248_1212 (murD)
11819-97:
MS7_1140 (murD)
6850:
RSAU_001064 (murD)
71193:
ST398NM01_1180
ECT-R 2:
ECTR2_1039 (murD)
ED133:
SAOV_1184
ED98:
SAAV_1154 (murD)
HO 5096 0412:
SAEMRSA15_10160 (murD)
JH1:
SaurJH1_1267 (murD)
JH9:
SaurJH9_1242 (murD)
JKD6008:
SAA6008_01137 (murD)
JKD6159:
SAA6159_01034 (murD)
LGA251:
SARLGA251_10940 (murD)
M013:
M013TW_1117
MRSA252:
SAR1159 (murD)
MSHR1132:
SAMSHR1132_10250
MSSA476:
SAS1117 (murD)
Mu3:
SAHV_1173 (murD)
Mu50:
SAV1183 (murD)
MW2:
MW1066 (murD)
RF122:
SAB1047 (murD)
ST398:
SAPIG1180 (murD)
T0131:
SAT0131_01228 (rplW)
TCH60:
HMPREF0772_12049 (murD)
TW20:
SATW20_11770 (murD)
USA300_TCH1516:
USA300HOU_1123 (murD)
VC40:
SAVC_05080 (murD)

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVV
  N315            MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVV
  NCTC8325        MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVV
  Newman          MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVV
  USA300_FPR3757  MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVV
                  ************************************************************
  
  COL             SGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTN
  N315            SGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTN
  NCTC8325        SGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTN
  Newman          SGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTN
  USA300_FPR3757  SGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTN
                  ************************************************************
  
  COL             GKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKP
  N315            GKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKP
  NCTC8325        GKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKP
  Newman          GKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKP
  USA300_FPR3757  GKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKP
                  ************************************************************
  
  COL             HIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLY
  N315            HIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLY
  NCTC8325        HIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLY
  Newman          HIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLY
  USA300_FPR3757  HIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLY
                  ************************************************************
  
  COL             FSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIID
  N315            FSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIID
  NCTC8325        FSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIID
  Newman          FSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIID
  USA300_FPR3757  FSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIID
                  ************************************************************
  
  COL             SLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFD
  N315            SLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFD
  NCTC8325        SLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFD
  Newman          SLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFD
  USA300_FPR3757  SLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFD
                  ************************************************************
  
  COL             ELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSP
  N315            ELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSP
  NCTC8325        ELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSP
  Newman          ELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSP
  USA300_FPR3757  ELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSP
                  ************************************************************
  
  COL             ACASWDQYSTFEERGEKFIERFRAHLPSY
  N315            ACASWDQYSTFEERGEKFIERFRAHLPSY
  NCTC8325        ACASWDQYSTFEERGEKFIERFRAHLPSY
  Newman          ACASWDQYSTFEERGEKFIERFRAHLPSY
  USA300_FPR3757  ACASWDQYSTFEERGEKFIERFRAHLPSY
                  *****************************