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Summary[edit | edit source]

  • pan ID?: SAUPAN003942000
  • symbol?: cmk
  • synonym:
  • description?: cytidylate kinase

      descriptions from strain specific annotations:

    • cytidylate kinase
    • (d)CMP kinase
    • cytidine monophosphate kinase
  • strand?: -
  • coordinates?: 4257664..4258323
  • synteny block?: BlockID0029880
  • occurrence?: in 100% of 33 strains

cmk: cytidine monophosphate kinase [1]

• equivalent enzyme nomenclature: "cytidylate kinase"

• a crystal structure is available: 2H92

Orthologs[edit | edit source]

    COL:
    SACOL1518 (cmk)
    N315:
    SA1309 (cmk)
    NCTC8325:
    Newman:
    NWMN_1386 (cmk)
    USA300_FPR3757:
    04-02981:
    SA2981_1434 (cmk)
    08BA02176:
    C248_1518 (cmk)
    11819-97:
    MS7_1431 (cmk)
    6850:
    RSAU_001348 (cmk)
    71193:
    ST398NM01_1476
    ECT-R 2:
    ECTR2_1329 (cmk)
    ED133:
    SAOV_1484 (cmk)
    ED98:
    SAAV_1464 (cmk)
    HO 5096 0412:
    SAEMRSA15_13370 (cmk)
    JH1:
    SaurJH1_1565 (cmk)
    JH9:
    SaurJH9_1534 (cmk)
    JKD6008:
    SAA6008_01446 (cmk)
    JKD6159:
    SAA6159_01341 (cmk)
    LGA251:
    SARLGA251_13900 (cmk)
    M013:
    M013TW_1424
    MRSA252:
    SAR1486 (cmk)
    MSHR1132:
    SAMSHR1132_13160
    MSSA476:
    SAS1418 (cmk)
    Mu3:
    SAHV_1466 (cmk)
    Mu50:
    SAV1478 (cmk)
    MW2:
    MW1366 (cmk)
    RF122:
    SAB1340c (cmk)
    ST398:
    SAPIG1476 (cmk)
    T0131:
    SAT0131_01566
    TCH60:
    HMPREF0772_11728 (cmk)
    TW20:
    SATW20_14750 (cmk)
    USA300_TCH1516:
    USA300HOU_1415 (cmk)
    VC40:
    SAVC_06635 (cmk)

Genome Viewer[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

Alignments[edit | edit source]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.307)


    COL             MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQ
    N315            MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQ
    NCTC8325        MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQ
    Newman          MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQ
    USA300_FPR3757  MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQ
                    ************************************************************

    COL             TTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKG
    N315            TTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKG
    NCTC8325        TTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKG
    Newman          TTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKG
    USA300_FPR3757  TTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKG
                    ************************************************************

    COL             IVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYD
    N315            IVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYD
    NCTC8325        IVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYD
    Newman          IVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYD
    USA300_FPR3757  IVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYD
                    ************************************************************

    COL             MNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQIK
    N315            MNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQIK
    NCTC8325        MNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQIK
    Newman          MNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQIK
    USA300_FPR3757  MNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQIK
                    ***************************************

  1. Balvinder Dhaliwal, Jingshan Ren, Michael Lockyer, Ian Charles, Alastair R Hawkins, David K Stammers
    Structure of Staphylococcus aureus cytidine monophosphate kinase in complex with cytidine 5'-monophosphate.
    Acta Crystallogr Sect F Struct Biol Cryst Commun: 2006, 62(Pt 8);710-5
    [PubMed:16880539] [WorldCat.org] [DOI] (I p)