⊟Summary[edit | edit source]
- pan ID?: SAUPAN004084000
- symbol?: —
- synonym:
- description?: IS30 family transposase
- IS30 family transposase
- pseudogene
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4364054..4368893
- synteny block?: BlockID0031160
- occurrence?: in 9% of 34 strains
tnpSau5 : ICE6013 insertion sequence Sau5 family transposase [1] [1]
All microbial genomes, including Staphylococci, contain mobile genetic elements integrated into their chromosomes that can mediate horizontal gene transfer. Sau5 family transposases are similar to the insertion sequence 30 family of mobile genetic elements flanked by inverted repeat sequences: IRL: CAACTCCCTATACGCTTTAGCGRTGGTATYGGGAGTTGATGAACATATAT and IRR: GATRAACCTATATTAATTGACGGGTTCGTGCCTCACACAGTCATTTAATA. It is characterized by ribosomal slippage at the recoding motif: AGTATCGGCTC AAAAAG TATAATAATCGT resulting in a 339 amino acid product across two distinct reading frames. ISSau5 is also the transposase responsible for mobilizing integrative chromosomal element 6013 (ICE6013).
⊟Orthologs[edit | edit source]
⊟Genome Viewer[edit | edit source]
| COL | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues:
- ↑ Zita Nagy, Mónika Szabó, Michael Chandler, Ferenc Olasz
Analysis of the N-terminal DNA binding domain of the IS30 transposase.
Mol Microbiol: 2004, 54(2);478-88
[PubMed:15469518] [WorldCat.org] [DOI] (P p)Emily A Sansevere, Xiao Luo, Joo Youn Park, Sunghyun Yoon, Keun Seok Seo, D Ashley Robinson
Transposase-Mediated Excision, Conjugative Transfer, and Diversity of ICE6013 Elements in Staphylococcus aureus.
J Bacteriol: 2017, 199(8);
[PubMed:28138100] [WorldCat.org] [DOI] (I e)