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⊟Summary[edit | edit source]
- pan ID?: SAUPAN004235000
- symbol?: aspS
- synonym:
- description?: aspartyl-tRNA synthetase
- aspartyl-tRNA synthetase
- aspartate--tRNA ligase
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4479416..4481182
- synteny block?: BlockID0032630
- occurrence?: in 100% of 33 strains
aspS (aspRS) aspartyl-/asparaginyl-tRNA synthetase [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1588 (aspS)
08BA02176:
C248_1673 (aspS)
11819-97:
MS7_1645 (aspS)
6850:
RSAU_001491 (aspS)
71193:
ST398NM01_1693
ECT-R 2:
ECTR2_1478 (aspS)
ED133:
SAOV_1627 (aspS)
ED98:
SAAV_1623 (aspS)
HO 5096 0412:
SAEMRSA15_15470 (aspS)
JH1:
SaurJH1_1720 (aspS)
JH9:
SaurJH9_1687 (aspS)
JKD6008:
SAA6008_01599 (aspS)
JKD6159:
SAA6159_01562 (aspS)
LGA251:
SARLGA251_15320 (aspS)
M013:
M013TW_1650
MRSA252:
SAR1710 (aspS)
MSHR1132:
SAMSHR1132_14660
MSSA476:
SAS1566 (aspS)
Mu3:
SAHV_1617 (aspS)
Mu50:
SAV1630 (aspS)
MW2:
MW1580 (aspS)
RF122:
SAB1499c (aspS)
ST398:
SAPIG1693 (aspS)
T0131:
SAT0131_01728 (sdrC)
TCH60:
HMPREF0772_11512 (aspS)
TW20:
SATW20_16240 (aspS)
USA300_TCH1516:
USA300HOU_1628 (aspS)
VC40:
SAVC_07395 (aspS)
⊟Genome Viewer[edit | edit source]
COL | |
N315 | |
NCTC8325 | |
Newman | |
USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEAL
N315 MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEAL
NCTC8325 MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEAL
Newman MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEAL
USA300_FPR3757 MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEAL
************************************************************
COL KIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENV
N315 KIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENV
NCTC8325 KIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENV
Newman KIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENV
USA300_FPR3757 KIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENV
************************************************************
COL NVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGAR
N315 NVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGAR
NCTC8325 NVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGAR
Newman NVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGAR
USA300_FPR3757 NVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGAR
************************************************************
COL DYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDI
N315 DYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDI
NCTC8325 DYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDI
Newman DYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDI
USA300_FPR3757 DYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDI
************************************************************
COL EMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELI
N315 EMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELI
NCTC8325 EMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELI
Newman EMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELI
USA300_FPR3757 EMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELI
************************************************************
COL DVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVK
N315 DVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVK
NCTC8325 DVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVK
Newman DVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVK
USA300_FPR3757 DVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVK
************************************************************
COL VVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELG
N315 VVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELG
NCTC8325 VVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELG
Newman VVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELG
USA300_FPR3757 VVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELG
************************************************************
COL LIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIV
N315 LIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIV
NCTC8325 LIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIV
Newman LIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIV
USA300_FPR3757 LIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIV
************************************************************
COL LNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDR
N315 LNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDR
NCTC8325 LNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDR
Newman LNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDR
USA300_FPR3757 LNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDR
************************************************************
COL LVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
N315 LVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
NCTC8325 LVMLLTNRTNLRDTIAFPKTASATCLLTNAPSEVSDKQLEELSLRIRH
Newman LVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
USA300_FPR3757 LVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
*******************************.****************
- ↑ Stefani R Mladenova, Kathryn R Stein, Lianne Bartlett, Kelly Sheppard
Relaxed tRNA specificity of the Staphylococcus aureus aspartyl-tRNA synthetase enables RNA-dependent asparagine biosynthesis.
FEBS Lett: 2014, 588(9);1808-12
[PubMed:24685427] [WorldCat.org] [DOI] (I p)