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Summary[edit | edit source]

  • pan ID?: SAUPAN004761000
  • symbol?:
  • synonym:
  • description?: multidrug ABC transporter ATP-binding protein

      descriptions from strain specific annotations:

    • multidrug ABC transporter ATP-binding protein
    • ABC transporter permease
    • putative ABC transporter protein EcsB
    • ABC transporter EcsB
    • ABC superfamily ATP binding cassette transporter, membrane protein
    • ABC transporter
    • ABC transporter ATP-binding protein
    • ABC transporter permease EscB
    • ABC transporter protein EcsB family protein
    • ABC-type exoprotein transport system, permease component
    • bacterial ABC transporter EcsB family protein
    • putative transporter protein
  • strand?: -
  • coordinates?: 4974710..4975837
  • synteny block?: BlockID0036930
  • occurrence?: in 100% of 33 strains

ecsB: linear exopeptide transport system permease subunit [1]

Orthologs[edit | edit source]

    COL:
    N315:
    NCTC8325:
    Newman:
    USA300_FPR3757:
    04-02981:
    SA2981_1792 (ecsB)
    08BA02176:
    C248_1877
    11819-97:
    MS7_1841
    6850:
    RSAU_001695 (ecsB)
    71193:
    ST398NM01_1901
    ECT-R 2:
    ECTR2_1678
    ED133:
    SAOV_1831
    ED98:
    SAAV_1855
    HO 5096 0412:
    SAEMRSA15_17400
    JH1:
    SaurJH1_1923
    JH9:
    SaurJH9_1889
    JKD6008:
    SAA6008_01793 (ecsB)
    JKD6159:
    SAA6159_01764 (ecsB)
    LGA251:
    SARLGA251_17190
    M013:
    M013TW_1842
    MRSA252:
    SAR1927
    MSHR1132:
    SAMSHR1132_16820
    MSSA476:
    SAS1757
    Mu3:
    SAHV_1821
    Mu50:
    SAV1836
    MW2:
    MW1776
    RF122:
    SAB1767c
    ST398:
    SAPIG1901
    T0131:
    SAT0131_01956
    TCH60:
    HMPREF0772_11309
    TW20:
    SATW20_18300
    USA300_TCH1516:
    USA300HOU_1828
    VC40:
    SAVC_08410

Genome Viewer[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

Alignments[edit | edit source]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.307)


    COL             MRNQATTLFNKRLHALRKEKNYYNKFIFNGHFMVFLLILLGAFIFGYGEWLKHIPTNINF
    N315            MHNQATTLFNKRLHALRKEKNYYNKFIFNGHFMVFLLILLGAFIFGYGEWLKHIPTNINF
    NCTC8325        MRNQATTLFNKRLHALRKEKNYYNKFIFNGHFMVFLLILLGAFIFGYGEWLKHIPTNINF
    Newman          MRNQATTLFNKRLHALRKEKNYYNKFIFNGHFMVFLLILLGAFIFGYGEWLKHIPTNINF
    USA300_FPR3757  MRNQATTLFNKRLHALRKEKNYYNKFIFNGHFMVFLLILLGAFIFGYGEWLKHIPTNINF
                    *:**********************************************************

    COL             SLIAAVIVALTSIFPMRPLLKEADKIFLLPFEKHMSQFMRHAILYSYFARILIQLIIVIV
    N315            ALIAAVIVALTSIFPMRPLLKEADKIFLLPFEKHMSQFMRHAILYSYFARILIQLIIVIV
    NCTC8325        SLIAAVIVALTSIFPMRPLLKEADKIFLLPFEKHMSQFMRHAILYSYFARILIQLIIVIV
    Newman          SLIAAVIVALTSIFPMRPLLKEADKIFLLPFEKHMSQFMRHAILYSYFARILIQLIIVIV
    USA300_FPR3757  SLIAAVIVALTSIFPMRPLLKEADKIFLLPFEKHMSQFMRHAILYSYFARILIQLIIVIV
                    :***********************************************************

    COL             MFPLFYNINQHNVAFYICFGVSALIFPYVGLRLRWQWYQSGLKTWQVNLISFITFALTYY
    N315            MFPLFYNINQHNVAFYICFGFSALIFPYVGLRLRWQWYQSGLKTWQVNLISFIIFALTYY
    NCTC8325        MFPLFYNINQHNVAFYICFGVSALIFPYVGLRLRWQWYQSGLKTWQVNLISFITFALTYY
    Newman          MFPLFYNINQHNVAFYICFGVSALIFPYVGLRLRWQWYQSGLKTWQVNLISFITFALTYY
    USA300_FPR3757  MFPLFYNINQHNVAFYICFGVSALIFPYVGLRLRWQWYQSGLKTWQVNLISFITFALTYY
                    ********************.******************************** ******

    COL             LLLAPKWYIAFVMVALPVLIEFLVKKYKPGFLYPWEKMIAIEHRHHMNYYKFVNMFTDVK
    N315            LLLAPKWYIVFVMVALPVLIEFLVKKYKPGFLYPWEKMIAIEHRHHMNYYKFVNMFTDVK
    NCTC8325        LLLAPKWYIAFVMVALPVLIEFLVKKYKPGFLYPWEKMIAIEHRHHMNYYKFVNMFTDVK
    Newman          LLLAPKWYIAFVMVALPVLIEFLVKKYKPGFLYPWEKMIAIEHRHHMNYYKFVNMFTDVK
    USA300_FPR3757  LLLAPKWYIAFVMVALPVLIEFLVKKYKPGFLYPWEKMIAIEHRHHMNYYKFVNMFTDVK
                    *********.**************************************************

    COL             HLKESAVRRSYLDILLPVPKGSKFNSNAMYLFLFIRSFIRGRDAFNIIFRLVIIAVLLMV
    N315            HLKESAVRRSYLDILLPVPKGSKFNSNAMYLFLFIRSFIRGRDAFNIIFRLVIIAVLLMV
    NCTC8325        HLKESAVRRSYLDILLPVPKGSKFNSNAMYLFLFIRSFIRGRDAFNIIFRLVIIAVLLMV
    Newman          HLKESAVRRSYLDILLPVPKGSKFNSNAMYLFLFIRSFIRGRDAFNIIFRLVIIAVLLMV
    USA300_FPR3757  HLKESAVRRSYLDILLPVPKGSKFNSNAMYLFLFIRSFIRGRDAFNIIFRLVIIAVLLMV
                    ************************************************************

    COL             WLSYPLVTAIIGCLFVYIILLQMAQFYSQQAYGLWPQVWPVPEEKVIKGYEQFLYRLMFV
    N315            WLSYPLVTGVIGSLFVYIILLQMAQFYSQQAYGLWPQVWPVPEEKVIKGYEQFLYRLMFV
    NCTC8325        WLSYPLVTAIIGCLFVYIILLQMAQFYSQQAYGLWPQVWPVPEEKVIKGYEQFLYRLMFV
    Newman          WLSYPLVTAIIGCLFVYIILLQMAQFYSQQAYGLWPQVWPVPEEKVIKGYEQFLYRLMFV
    USA300_FPR3757  WLSYPLVTAIIGCLFVYIILLQMAQFYSQQAYGLWPQVWPVPEEKVIKGYEQFLYRLMFV
                    ********.:**.***********************************************

    COL             ICTVFAVTFIIKHMTLFYVVLIFYIVGLLTIRSIIKKLKYQETLLRD
    N315            ICTVFAVTFIIKHMTLFYVVLIFYIVGLLTIRSIIKKLKYQETLLRD
    NCTC8325        ICTVFAVTFIIKHMTLFYVVLIFYIVGLLTIRSIIKKLKYQETLLRD
    Newman          ICTVFAVTFIIKHMTLFYVVLIFYIVGLLTIRSIIKKLKYQETLLRD
    USA300_FPR3757  ICTVFAVTFIIKHMTLFYVVLIFYIVGLLTIRSIIKKLKYQETLLRD
                    ***********************************************

  1. Ing-Marie Jonsson, Jarmo T Juuti, Patrice François, Rana AlMajidi, Milla Pietiäinen, Myriam Girard, Catharina Lindholm, Manfred J Saller, Arnold J M Driessen, Pentti Kuusela, Maria Bokarewa, Jacques Schrenzel, Vesa P Kontinen
    Inactivation of the Ecs ABC transporter of Staphylococcus aureus attenuates virulence by altering composition and function of bacterial wall.
    PLoS One: 2010, 5(12);e14209
    [PubMed:21151985] [WorldCat.org] [DOI] (I e)
    Katrin Schilcher, Lindsay K Caesar, Nadja B Cech, Alexander R Horswill
    Processing, Export, and Identification of Novel Linear Peptides from Staphylococcus aureus.
    mBio: 2020, 11(2);
    [PubMed:32291297] [WorldCat.org] [DOI] (I e)