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Summary[edit | edit source]

  • pan ID?: SAUPAN004762000
  • symbol?: ecsA
  • synonym:
  • description?: ABC transporter ATP-binding protein

      descriptions from strain specific annotations:

    • ABC transporter ATP-binding protein
    • ABC transporter ATP-binding protein EcsA
    • ABC transporter EcsA, ATP-binding protein
    • ABC-type transporter ATP-binding protein ecsA
    • ABC superfamily ATP binding cassette transporter, ABC protein
    • ABC transporter
    • ABC transporter ecsA
    • ATP-binding ABC transporter
    • multidrug ABC transporter
  • strand?: -
  • coordinates?: 4975926..4976666
  • synteny block?: BlockID0036940
  • occurrence?: in 100% of 33 strains

ecsA: linear exopeptide transport system ATP-binding subunit [1]

Orthologs[edit | edit source]

    COL:
    N315:
    NCTC8325:
    Newman:
    USA300_FPR3757:
    04-02981:
    SA2981_1793 (ecsA)
    08BA02176:
    C248_1878
    11819-97:
    MS7_1842 (ecsA)
    6850:
    RSAU_001696 (ecsA)
    71193:
    ST398NM01_1902
    ECT-R 2:
    ECTR2_1679
    ED133:
    SAOV_1832
    ED98:
    SAAV_1856
    HO 5096 0412:
    SAEMRSA15_17410
    JH1:
    SaurJH1_1924
    JH9:
    SaurJH9_1890
    JKD6008:
    SAA6008_01794 (ccmA)
    JKD6159:
    SAA6159_01765 (ccmA)
    LGA251:
    SARLGA251_17200
    M013:
    M013TW_1843
    MRSA252:
    SAR1928
    MSHR1132:
    SAMSHR1132_16830
    MSSA476:
    SAS1758
    Mu3:
    SAHV_1822
    Mu50:
    SAV1837
    MW2:
    MW1777
    RF122:
    SAB1768c
    ST398:
    SAPIG1902
    T0131:
    SAT0131_01957
    TCH60:
    HMPREF0772_11308
    TW20:
    SATW20_18310
    USA300_TCH1516:
    USA300HOU_1829
    VC40:
    SAVC_08415

Genome Viewer[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

Alignments[edit | edit source]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.307)


    COL             MTVKVEQLTGGYGKRPVIKDINFELNKGEIVGLIGLNGAGKSTTIKHMLGLLTPMEGSLS
    N315            MTVKVEQLTGGYGKRPVIKDINFELNKGEIVGLIGLNGAGKSTTIKHMLGLLTPMEGSLS
    NCTC8325        MTVKVEQLTGGYGKRPVIKDINFELNKGEIVGLIGLNGAGKSTTIKHMLGLLTPMEGSLS
    Newman          MTVKVEQLTGGYGKRPVIKDINFELNKGEIVGLIGLNGAGKSTTIKHMLGLLTPMEGSLS
    USA300_FPR3757  MTVKVEQLTGGYGKRPVIKDINFELNKGEIVGLIGLNGAGKSTTIKHMLGLLTPMEGSLS
                    ************************************************************

    COL             ISDININDDIEAYRRKLSYIPESPVIYEELTLEEHIEMTAMAYDIDRDETMNRAMPLLKT
    N315            ISDININDDIEAYRRKLSYIPESPVIYEELTLEEHIEMTAMAYDIDRDEAMNRAMPLLKT
    NCTC8325        ISDININDDIEAYRRKLSYIPESPVIYEELTLEEHIEMTAMAYDIDRDETMNRAMPLLKT
    Newman          ISDININDDIEAYRRKLSYIPESPVIYEELTLEEHIEMTAMAYDIDRDETMNRAMPLLKT
    USA300_FPR3757  ISDININDDIEAYRRKLSYIPESPVIYEELTLEEHIEMTAMAYDIDRDETMNRAMPLLKT
                    *************************************************:**********

    COL             FRLENELKVFPSHFSKGMKQKVMIICAFIVNPELYIIDEPFLGLDPLGIQSMLDLMVEKK
    N315            FRLENELKVFPSHFSKGMKQKVMIICAFIVNPELYIIDEPFLGLDPLGIQSMLDLMVEKK
    NCTC8325        FRLENELKVFPSHFSKGMKQKVMIICAFIVNPELYIIDEPFLGLDPLGIQSMLDLMVEKK
    Newman          FRLENELKVFPSHFSKGMKQKVMIICAFIVNPELYIIDEPFLGLDPLGIQSMLDLMVEKK
    USA300_FPR3757  FRLENELKVFPSHFSKGMKQKVMIICAFIVNPELYIIDEPFLGLDPLGIQSMLDLMVEKK
                    ************************************************************

    COL             NEGRTVLMSTHILATAERYCDRFIILDEGEVVAFGDLEALRQQTGLHNQTLDDIYIHVTQ
    N315            NEGRTVLMSTHILATAERYCDRFIILDEGEVVAFGDLEALRQQTGLHNQTLDDIYIHVTQ
    NCTC8325        NEGRTVLMSTHILATAERYCDRFIILDEGEVVAFGDLEALRQQTGLHNQTLDDIYIHVTQ
    Newman          NEGRTVLMSTHILATAERYCDRFIILDEGEVVAFGDLEALRQQTGLHNQTLDDIYIHVTQ
    USA300_FPR3757  NEGRTVLMSTHILATAERYCDRFIILDEGEVVAFGDLEALRQQTGLHNQTLDDIYIHVTQ
                    ************************************************************

    COL             GGDVHA
    N315            GGDVHA
    NCTC8325        GGDVHA
    Newman          GGDVHA
    USA300_FPR3757  GGDVHA
                    ******

  1. Ing-Marie Jonsson, Jarmo T Juuti, Patrice François, Rana AlMajidi, Milla Pietiäinen, Myriam Girard, Catharina Lindholm, Manfred J Saller, Arnold J M Driessen, Pentti Kuusela, Maria Bokarewa, Jacques Schrenzel, Vesa P Kontinen
    Inactivation of the Ecs ABC transporter of Staphylococcus aureus attenuates virulence by altering composition and function of bacterial wall.
    PLoS One: 2010, 5(12);e14209
    [PubMed:21151985] [WorldCat.org] [DOI] (I e)
    Katrin Schilcher, Lindsay K Caesar, Nadja B Cech, Alexander R Horswill
    Processing, Export, and Identification of Novel Linear Peptides from Staphylococcus aureus.
    mBio: 2020, 11(2);
    [PubMed:32291297] [WorldCat.org] [DOI] (I e)