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⊟Summary[edit | edit source]
- pan ID?: SAUPAN005945000
- symbol?: fmhA
- synonym:
- description?: aminoacyltransferase
- aminoacyltransferase
- fmhA protein
- FemA/FemB family glycyltransferase FmhA
- methicillin resistance determinant fmhA protein
- methicillin resistance determinant protein FmhA
- femAB family protein
- aminoacyltransferase femA
- aminoacyltransferase FemA (Factor essential forexpression of methicillin resistance A)
- FemAB family peptidoglycan biosynthesis protein
- FmhA protein of FemAB family
- lysostaphin endopeptidase resistance protein
- methicillin resistance protein
- pseudogene
- UDP-N-acetylmuramoylheptapeptide-glycine L-seryltransferase
descriptions from strain specific annotations:
- strand?: +
- coordinates?: 6008897..6010147
- synteny block?: BlockID0046890
- occurrence?: in 100% of 34 strains
fmhA : lipid II-monopeptide/lipid II-tripeptide:glycylserine aminoacyltransferase [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2348 (fmhA)
08BA02176:
C248_2456 (fmhA)
11819-97:
MS7_2426
6850:
RSAU_002249 (fmhA)
71193:
ST398NM01_2462
ECT-R 2:
ECTR2_2270
ED133:
SAOV_2457
ED98:
SAAV_2476 (fmhA)
HO 5096 0412:
SAEMRSA15_23100 (fmhA)
JH1:
SaurJH1_2484
JH9:
SaurJH9_2436
JKD6008:
SAA6008_02452 (fmhA)
JKD6159:
SAA6159_02312 (fmhA)
JSNZ:
JSNZ_002382 (fmhA)
LGA251:
SARLGA251_21930 (fmhA)
M013:
M013TW_2372
MRSA252:
SAR2501 (fmhA)
MSHR1132:
SAMSHR1132_22390
MSSA476:
SAS2302
Mu3:
SAHV_2395 (fmhA)
Mu50:
SAV2411 (fmhA)
MW2:
MW2333 (fmhA)
RF122:
SAB2291 (fmhA)
ST398:
SAPIG2462
T0131:
SAT0131_02602
TCH60:
HMPREF0772_10776 (fmhA)
TW20:
SATW20_25410 (fmhA)
USA300_TCH1516:
USA300HOU_2392
VC40:
SAVC_10925
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEA
N315 MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEA
NCTC8325 MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEA
Newman MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEA
USA300_FPR3757 MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEA
************************************************************
COL RTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCLYVLVDPYLIENLRNADGE
N315 RTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCLYVLVDPYLIENLRNADGE
NCTC8325 RTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCLYVLVDPYLIENLRNADGE
Newman RTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCLYVLVDPYLIENLRNADGE
USA300_FPR3757 RTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCLYVLVDPYLIENLRNADGE
************************************************************
COL IVKSYDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRR
N315 IVKSYDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRR
NCTC8325 IVKSYDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRR
Newman IVKSYDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRR
USA300_FPR3757 IVKSYDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRR
************************************************************
COL NIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLA
N315 NIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLA
NCTC8325 NIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLA
Newman NIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLA
USA300_FPR3757 NIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLA
************************************************************
COL YIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTKRTQLEQQLNSNKRKIDNTI
N315 YIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTKRTQLEQQLNSNKRKIDNTI
NCTC8325 YIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTKRTQLEQQLNSNKRKIDNTI
Newman YIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTKRTQLEQQLNSNKRKIDNTI
USA300_FPR3757 YIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTKRTQLEQQLNSNKRKIDNTI
************************************************************
COL EQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRY
N315 EQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRY
NCTC8325 EQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRY
Newman EQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRY
USA300_FPR3757 EQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRY
************************************************************
COL NFYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYKVQTYLNHKRR
N315 NFYGITGDYSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYKVQTYLNHKRR
NCTC8325 NFYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYKVQTYLNHKRR
Newman NFYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYKVQTYLNHKRR
USA300_FPR3757 NFYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYKVQTYLNHKRR
********:***********************************************
- ↑ Stephanie Willing, Emma Dyer, Olaf Schneewind, Dominique Missiakas
FmhA and FmhC of Staphylococcus aureus incorporate serine residues into peptidoglycan cross-bridges.
J Biol Chem: 2020, 295(39);13664-13676
[PubMed:32759309] [WorldCat.org] [DOI] (I p)