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⊟Summary[edit | edit source]
- pan ID?: SAUPAN006073000
- symbol?: —
- synonym:
- description?: tandem-type lipoprotein
- tandem-type lipoprotein
- lipoprotein, putative
- tandem lipoprotein
- lipoprotein
- Membrane lipoprotein
- putative lipoprotein
- staphylococcus tandem lipoproteins family protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 6118331..6132694
- synteny block?: BlockID0048140
- occurrence?: in 76% of 34 strains
tilB1 : tandem TslB phospholipase immunity lipoprotein paralogue TilB1 [1]
Provides immunity to TslB interspecies competition phospholipases. Neighboring paralogues provide recombinatorial capacity for rapid structural modification to inhibit multiple TslB structural variants.
⊟Orthologs[edit | edit source]
04-02981:
SA2981_2424
08BA02176:
C248_2544
11819-97:
—
6850:
RSAU_002326
71193:
ST398NM01_2543
ECT-R 2:
ECTR2_2344
ED133:
—
ED98:
SAAV_2554
HO 5096 0412:
SAEMRSA15_23870
JH1:
SaurJH1_2566
JH9:
SaurJH9_2514
JKD6008:
SAA6008_02523
JKD6159:
SAA6159_02382
JSNZ:
JSNZ_002467
LGA251:
SARLGA251_22680
M013:
M013TW_2449
MRSA252:
—
MSHR1132:
—
MSSA476:
—
Mu3:
SAHV_2471
Mu50:
SAV2487
MW2:
—
RF122:
—
ST398:
SAPIG2543
T0131:
SAT0131_02683 (proS)
TCH60:
—
TW20:
SATW20_26090
USA300_TCH1516:
USA300HOU_2478
VC40:
SAVC_11310
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MMIHSKRLRLWLYLVLLAVFIGACGMKKEESSKDKQIKENFNKTLSLYPTKNLEDFYDKE
N315 MMIHSRKLRLWLYLVLLAVFIGACGMKKEESSKDKQIKENFNKTLSLYPTKNLEDFYDKE
NCTC8325 -------------------------MKKEESSKDKQIKENFNKTLSLYPTKNLEDFYDKE
Newman MMIHSKRLRLWLYLVLLAVFIGACGMKKEESSKDKQIKENFNKTLSLYPTKNLEDFYDKE
USA300_FPR3757 MMIHSKRLRLWLYLVLLAVFIGACGMKKEESSKDKQIKENFNKTLSLYPTKNLEDFYDKE
***********************************
COL GFRDQEFEKGDKGTWIIHSKMTIETNGKNMESRGLVLYVDRNTRTTKGEFIVRELWEDKK
N315 GFRDEEFEKGDKGTWIIHSKMTIETNGKNMESRGLVLYVDRNTRTTKGEFIVRELWEDKK
NCTC8325 GFRDQEFEKGDKGTWIIHSKMTIETNGKNMESRGLVLYVDRNTRTTKGEFIVRELWEDKK
Newman GFRDQEFEKGDKGTWIIHSKMTIETNGKNMESRGLVLYVDRNTRTTKGEFIVRELWEDKK
USA300_FPR3757 GFRDQEFEKGDKGTWIIHSKMTIETNGKNMESRGLVLYVDRNTRTTKGEFIVRELWEDKK
****:*******************************************************
COL GYSRSKEKEYPVKMEHNKIIPTKPIADDKLRKEIENFKFFVQYGDFKDINDYKDGDISYN
N315 GYSRSKEKEYPVKMEHNKIIPTKPIADDKLRKEIEDFKFFVQYGDFKDINDYKDGDISYN
NCTC8325 GYSRSKEKEYPVKMEHNKIIPTKPIADDKLRKEIENFKFFVQYGDFKDINDYKDGDISYN
Newman GYSRSKEKEYPVKMEHNKIIPTKPIADDKLRKEIENFKFFVQYGDFKDINDYKDGDISYN
USA300_FPR3757 GYSRSKEKEYPVKMEHNKIIPTKPIADDKLRKEIENFKFFVQYGDFKDINDYKDGDISYN
***********************************:************************
COL PNVPSYSAKYQLSNDDYNVKQLRKRYDIPTKKAPKLLIKGDGDLKGSSIGHKNLEFTFIE
N315 PNVPSYSAKYQLSNNDYNVKQLRKRYDIPTKKAPKLLLKGDGDLKGSSIGHKNLEFIFIE
NCTC8325 PNVPSYSAKYQLSNDDYNVKQLRKRYDIPTKKAPKLLIKGDGDLKGSSIGHKNLEFTFIE
Newman PNVPSYSAKYQLSNDDYNVKQLRKRYDIPTKKAPKLLIKGDGDLKGSSIGHKNLEFTFIE
USA300_FPR3757 PNVPSYSAKYQLSNDDYNVKQLRKRYDIPTKKAPKLLIKGDGDLKGSSIGHKNLEFTFIE
**************:**********************:****************** ***
COL NKEENIYFTDSINFKPTE
N315 NKEENIYFTDSINFKPTE
NCTC8325 NKEENIYFTDSINFKPTE
Newman NKEENIYFTDSINFKPTE
USA300_FPR3757 NKEENIYFTDSINFKPTE
******************
- ↑ Stephen R Garrett, Nicole Mietrach, Justin Deme, Alina Bitzer, Yaping Yang, Fatima R Ulhuq, Dorothee Kretschmer, Simon Heilbronner, Terry K Smith, Susan M Lea, Tracy Palmer
A type VII-secreted lipase toxin with reverse domain arrangement.
Nat Commun: 2023, 14(1);8438
[PubMed:38114483] [WorldCat.org] [DOI] (I e)