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⊟Summary[edit | edit source]

  • pan ID?: SAUPAN006210000
  • symbol?: clpL
  • synonym:
  • description?: ATP-dependent Clp protease ATP-binding subunit

      descriptions from strain specific annotations:

    • ATP-dependent Clp protease ATP-binding subunit
    • ATP-dependent Clp protease
    • ATP-dependent Clp protease, ATP-binding subunit ClpC
    • ATP-dependent Clp protease ATP-binding subunit ClpC
    • ATP-dependent Clp proteinase, ATP-binding subunit (ClpL)
    • ATP-dependent Clp proteinase subunit clpL
    • putative ATP-dependent Clp proteinase
    • ATP-dependent Clp protease ATP-binding subunit clpL
    • ATP-dependent protease ATP-binding subunit clpL
    • putative ATP-dependent protease ATP-bindingsubunit ClpL
    • AAA ATPase
    • ATPase
    • ATP-dependent Clp protease, putative
    • ATP-dependent Clp proteinase chain
    • ATP-dependent Clp proteinase chain clpL
    • ATP-dependent proteinase chain
    • chaperone ATPase
    • endopeptidase Clp
  • strand?: +
  • coordinates?: 6270264..6272385
  • synteny block?: BlockID0049340
  • occurrence?: in 100% of 33 strains

clpL: clp proteolytic system chaperone and ATP-binding subunit ClpL[1]

⊟Orthologs[edit | edit source]

    COL:
    SACOL2563
    N315:
    SA2336 (clpL)
    NCTC8325:
    SAOUHSC_02862
    Newman:
    NWMN_2448 (clpC)
    USA300_FPR3757:
    SAUSA300_2486
    04-02981:
    SA2981_2484 (clpL)
    08BA02176:
    C248_2605 (clpL)
    11819-97:
    MS7_2554
    6850:
    RSAU_002389 (clpL)
    71193:
    ST398NM01_2598
    ECT-R 2:
    ECTR2_2400
    ED133:
    SAOV_2592
    ED98:
    SAAV_2614
    HO 5096 0412:
    SAEMRSA15_24510 (clpL)
    JH1:
    SaurJH1_2624
    JH9:
    SaurJH9_2571
    JKD6008:
    SAA6008_02586
    JKD6159:
    SAA6159_02444
    LGA251:
    SARLGA251_23230 (clpL)
    M013:
    M013TW_2521
    MRSA252:
    SAR2628 (clpL)
    MSHR1132:
    SAMSHR1132_23680
    MSSA476:
    SAS2434
    Mu3:
    SAHV_2532 (clpL)
    Mu50:
    SAV2548 (clpL)
    MW2:
    MW2469 (clpL)
    RF122:
    SAB2423 (clpL)
    ST398:
    SAPIG2598
    T0131:
    SAT0131_02757
    TCH60:
    HMPREF0772_10643 (clpL)
    TW20:
    SATW20_26700 (clpL)
    USA300_TCH1516:
    USA300HOU_2542 (clp)
    VC40:
    SAVC_11620

⊟Genome Viewer[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments[edit | edit source]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.307)


    COL             MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSA
    N315            MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGSNQSAEQSA
    NCTC8325        MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSA
    Newman          MNNVFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSA
    USA300_FPR3757  MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSA
                    *** **************:********************************.*:******

    COL             QAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKN
    N315            QAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKN
    NCTC8325        QAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKN
    Newman          QAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKN
    USA300_FPR3757  QAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKN
                    ************************************************************

    COL             NPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQ
    N315            NPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQ
    NCTC8325        NPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQ
    Newman          NPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQ
    USA300_FPR3757  NPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQ
                    ************************************************************

    COL             KLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
    N315            KLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
    NCTC8325        KLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
    Newman          KLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
    USA300_FPR3757  KLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
                    ************************************************************

    COL             YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSI
    N315            YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSI
    NCTC8325        YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSI
    Newman          YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSI
    USA300_FPR3757  YRNNILKDSALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSI
                    ********:***************************************************

    COL             QYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADD
    N315            QYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADD
    NCTC8325        QYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADD
    Newman          QYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADD
    USA300_FPR3757  QYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADD
                    ************************************************************

    COL             IQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRS
    N315            IQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRS
    NCTC8325        IQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRS
    Newman          IQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRS
    USA300_FPR3757  IQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRS
                    ************************************************************

    COL             KIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
    N315            KIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
    NCTC8325        KIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
    Newman          KIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
    USA300_FPR3757  KIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
                    ************************************************************

    COL             LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQIL
    N315            LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQIL
    NCTC8325        LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQIL
    Newman          LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQIL
    USA300_FPR3757  LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQIL
                    ************************************************************

    COL             TLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLN
    N315            TLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLN
    NCTC8325        TLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLN
    Newman          TLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLN
    USA300_FPR3757  TLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLN
                    ************************************************************

    COL             RFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGAR
    N315            RFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGAR
    NCTC8325        RFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGAR
    Newman          RFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGAR
    USA300_FPR3757  RFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGAR
                    ************************************************************

    COL             PLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
    N315            PLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
    NCTC8325        PLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
    Newman          PLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
    USA300_FPR3757  PLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
                    *****************************************

  1. ↑ Dorte Frees, Arnaud Chastanet, Saara Qazi, Karen Sørensen, Philip Hill, Tarek Msadek, Hanne Ingmer
    Clp ATPases are required for stress tolerance, intracellular replication and biofilm formation in Staphylococcus aureus.
    Mol Microbiol: 2004, 54(5);1445-62
    [PubMed:15554981] [WorldCat.org] [DOI] (P p)
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